Meet the Creator of EndoMune Advanced Probiotic, Gastroenterologist Dr. Hoberman

Meet Dr. Larry Hoberman
Board-Certified Gastroenterologist
Creator of EndoMune Advanced Probiotic, EndoMune Advanced Junior, and EndoMune Metabolic Rescue
Public speaker, Expert on probiotics

Dr. Lawrence J. Hoberman is an expert in probiotics and digestive health issues. With his 40-plus year career in medicine, he has extensive first-hand experience treating a variety of health issues and has seen the dramatic results probiotics have on his own patients.

A prolific writer with a passion for keeping the public informed, Dr. Hoberman stays up-to-date through research and blogs about the latest trends and study results on his health blog: Trending topics include artificial sweeteners, the Paleo diet, leaky gut, and noroviruses.

He understands his audience’s needs, customizing his presentations to each (whether physicians, educators or the general public), while providing insights into how the topic affects their patients or them. He can also describe how he used his four decades of training and experience to develop his own probiotic, EndoMune Advanced Priobiotic, to help treat his patients’ digestive issues, and EndoMune Metablic Rescue to improve metabolic efficiency and natural, safe weight loss.


Born in Omaha, Nebraska, Dr. Hoberman developed a strong interest in medicine during high school, knowing he was going to be a doctor. After graduating from the University of Nebraska, he completed medical school at the University of Nebraska College of Medicine, went to the Indiana University Medical Center for his internship and began a residency in internal medicine. His residency training was interrupted when the U.S. Air Force recruited him. He was selected to be a flight surgeon and underwent training at Aerospace Medicine at Brook Air Force Base in San Antonio.

After completing his tour of duty, Dr. Hoberman completed his internal medicine residency at Wilford Hall Medical Center in San Antonio and later entered a two-year gastroenterology fellowship at Southwestern Medical School in Dallas. Following the fellowship and completing a year of active duty on the teaching faculty at Wilford Hall, he entered the private practice of gastroenterology in San Antonio. After 25 years treating patients as a gastroenterologist, he chose to enter the field of preventative medicine at Health by Design as Associate Director of Executive Exams.

Dr. Hoberman developed a holistic approach to medicine, becoming interested in the importance of the intestinal bacteria or microbiome for intestinal health and function. Frustrated by the lack of options to treat his patients suffering from Irritable Bowel Disease (IBD), Dr. H met with a PhD microbiologist to identify a combination of bacteria that might work to destroy the harmful bacteria living in the intestines, improving and maintaining the health of adults.

The result of his efforts was the formula of 10 bacteria strains and 20 billion colony-forming units (CFUs). EndoMune Advanced Probiotic ( for adults was introduced to the market in 2007. Two years later he developed a formula of 4 bacteria strains and 10 billion CFUs for children ages 8 and under. During the summer of 2013, EndoMune Advanced Junior became the first probiotic to be certified as Parent Tested Parent Approved, a North American Award. His latest supplement, EndoMune Metabolic Rescue, provides 2 billion CFUs of the beneficial Bifidobacterium lactis and 1200 mg of Xylooligosaccharides (XOS), a prebiotic fiber, to slow gastric emptying, and improve satiety and insulin sensitivity.


EndoMune Metabolic Rescue, 2018
EndoMune Advanced Junior Probiotic, 2009
EndoMune Advanced Probiotic, 2007

Speaking Engagements*

2016 Austin Gluten Free Food Allery Fest (April)
2015 Dallas Gluten Free & Allergen Friendly Expo (October)
2014 Texas Osteopathic Medical Association Conference
2014 Upgrade Your Health, Health & Happiness Empowerment Series (April)
2013 San Antonio Functional Medicine Group Conference
2013-2014 Regular Guest on Your Smile Matters with Dr. Ed Staffel
2012 Internal Conference and Exhibition on Probiotics


“Abdominal Pain, Angioedema, and Angiotensin- converting Enzyme Inhibitors.” K.M. Goldstein, 1994

“Same Day Peg Feeding, Is It Safe? Results of Randomized Prospective Study.” October 1993

“Medication Induced Esophagitis: Diagnostic by Double- Contrast Esophagograph.” April 1987

“A Point Source Outbreak of Chronic Diarrhea in Texas: No Known Exposure to Raw Milk.” JAMA, 1986

“Colitis Associated with Oral Clindamycin Therapy: A Clinical Study of Sixteen Patients.” American Journal of Digestive Diseases, 1976

“Serum Gamma-Glutamyl Transpeptidase Activity in Normal Children.” American Journal of Clinical Pathology, 1975

Professional Organizations

American College of Gastroenterology, Fellow
American Medical Association
Texas Medical Association
Bexar County Medical Society
American Gastroenterological Association
American Digestive Disease Society
Texas Society for Gastrointestinal Endoscopy
San Antonio Gut Club, President 1980-82
Gastroenterological Diagnostic Unit of Southwest
Texas Methodist Hospital, Director 1975-80, 1983-84, 1986-94
Department of Medicine at Southwest Texas
Methodist Hospital, Chairman 1980-82


The University of Texas Southwestern
Medical Center at Dallas
Board certified in Gastroenterology
1972 – 1974

Wilford Hall Medical Center
Gastroenterology fellowship
1970 – 1972

Indiana University Medical Center
Internal Medicine Residency Program
1967 – 1968

University of Nebraska
Doctor of Medicine (M.D.), Medicine
1963 – 1967

University of Nebraska
Bachelor’s degree, Political Science and Government
1961 – 1963

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Dr. Hoberman’s CV

Consult The Doctor

Want to know more about probiotics or just looking for information on how to live a happy, healthy life? Consult the EndoMune Blog! Written by Dr. Hoberman, each entry details new research, information and advice on maintaining your best health. Think of it as your own special, one-on-one time to have a personal consultation with Dr. Hoberman!