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Graphic depicting the digestive system. Text reads "The Probiotic Benefit for Gastric Bypass Patients"

The Probiotic Benefit For Gastric Bypass Patients

The Probiotic Benefit For Gastric Bypass Patients

With greater numbers of people struggling with a myriad of health issues surrounding obesity, the popularity of gastric bypass procedures that help patients shed extra pounds has grown exponentially over the past three decades.

Although gastric bypass isn’t for everyone who suffers from severe weight-related health problems, this procedure can be an important catalyst toward better health outcomes.

Losing the weight with the help of gastric bypass is merely the first step. It takes a great deal of work and mental determination to follow a healthier diet plan rather than a nutrient-poor Western diet which is often the reason many patients consider gastric bypass in the first place.

However, taking a probiotic formulated with Lactobacillus and Bifidobacterium strains may be a very safe, gut-friendly solution that eases some of the issues gastric bypass patients face, according to a recent study.

 

The Gut-Brain Connection At Work

A team of Brazilian researchers conducted a clinical trial with 101 gastric bypass patients to assess the gut-brain benefits of prescribing a probiotic containing Bifidobacterium lactis and Lactobacillus acidophilus, targeting symptoms of binge eating and food addictions.

(These strains of beneficial bacteria are among the 10 formulated in every bottle of EndoMune Advanced Probiotic.)

Patients received a multi-strain probiotic or placebo for three months, starting seven days after their gastric bypass surgeries, then were evaluated at the 90-day and 1-year marks to assess outcomes.

Both patient groups experienced decreases in symptoms at three months. But, the real benefit of taking a multi-strain probiotic showed up a year later as patients still experienced significant gut-brain relief from binging and food addictions.

 

What If Gastric Bypass Isn’t An Option?

For many people, gastric bypass may not be the best option to lose weight. You may not be keen on weight-loss surgery, especially if the amount of weight you need to lose is a much more manageable number that can be aided by eating nutrient-dense foods and increasing your exercise.

If you want to lose weight safely and more slowly but need some extra help, you may want to consider EndoMune Metabolic Rescue, a probiotic that can help you maintain the healthy balance of bacteria in your gut and jumpstart your weight loss plan.

EndoMune Metabolic Rescue contains a proven blend of Bifidobacterium lactis and the prebiotic XOS (Xylooligosaccharides) that stimulates the release of hormones in your gut that reduce your appetite naturally by promoting a greater sense of fullness.

If gastric bypass isn’t in your future, it’s good to know you have gut-healthy options in the EndoMune family of probiotics that can make your weight-loss journey a good experience.

 

References

ABCD (Arquivos Brasileiros de Cirurgia Digestiva)

Nutra Ingredients

Mayo Clinic

Porto Biomedical Journal

Medline Plus

Zoomed in image of many tomatoes piled up. Text says "Are tomatoes good for your gut?"

Are Tomatoes Good For Your Gut?

Are Tomatoes Good For Your Gut?

You’d be surprised by the number of calls we get every time a story pops up on the evening news about the latest probiotic food “discovery.”

Suggestions — whole foods like walnuts — make some sense, but others — beer or kombucha tea — are more challenging and depend on factors largely out of your control.

Recently, tomatoes joined that growing list of foods based on a joint study from a research team at Ohio State and Penn State University specializing in food, crop and animal sciences and the microbiome

Their focus made sense, given that tomatoes make up more than 20 percent of the vegetable intake in the average Western diet and their consumption has been associated with reduced risks for the development of some forms of cancer and cardiovascular disease.

However, there’s always caveats when it comes to evaluating the efficacy of most foods in the laboratory for their microbial benefits, and this case is no different.

 

How Tomatoes Affect The Gut

To measure the benefits, scientists fed two sets of recently weaned pigs either a standard diet or one that was fine-tuned slightly to include a 10 percent mix of freeze-dried powder made from tomatoes for two weeks.

Gut changes were measured from fecal samples taken before the study started, then seven and 14 days after the tomato-laden diet started. Then, researchers used shotgun metagenomic sequencing, a technique used to sequence genomes to calculate the composition of microbes, to compare those samples.

Overall, the pigs eating a tomato-based diet experienced increased gut microbial diversity, and higher ratios of beneficial bacteria linked to good health outcomes. For example, previous research has linked tomato consumption with a lower risk of cardiovascular disease and some cancers.

Although the results were positive and measurable among animals eating tomatoes, scientists did not learn how or why that change occurred.

That said, pigs have GI tracts that more closely resemble those in humans than mice, which suggests a future trial in humans could happen, says Dr. Jessica Cooperstone, senior study author and an assistant professor at Ohio State.

 

The Takeaway For Your Health

Still, the real unknown is understanding how foods like tomatoes make an impact on human gut health, says Dr. Cooperstone.

Even taking these positive results into account, the real test for any food is to consume enough of it to have a positive impact on the balance of bacteria in your gut without creating more health problems, like worsening conditions like GERD (gastroesophageal reflux) or migraines.

Very simply, it’s hard to eat enough of a single food to make a gut healthy difference, but a diet rich in dietary fiber can do a lot of good and only takes about 1 ounce of fiber a day to notice a difference.

But there’s more you can do to give your health a gut-friendly boost every day, especially if you have a hard time eating enough fiber.

Taking a multi-strain probiotic formulated with beneficial bacteria from the Lactobacillus and Bifidobacterium families and a proven prebiotic (FOS) contained in EndoMune Advanced Probiotic every day can make a gut-healthy difference in your health.

And, you can save the tomatoes for a salad or your favorite sandwich…

 

References

Microbiology Spectrum

Ohio State News

Health

News-medical.net

Illustration of the digestive system and circulatory system in the human body. Text says "Your gut or your blood: what affects your health more?"

Your Gut or Your Blood: What Affects Your Health More?

Your Gut or Your Blood: What Affects Your Health More?

We posted an article last year that asked a provocative question about what affects your health more: Your gut or your genes.

From that report, we learned once again how the quality of our daily diets shaped the diversity of our microbiomes in ways that can leave us more vulnerable to serious health problems or protect us from them.

That’s not all, according to a pair of recent studies conducted in Sweden and America.

The human gut exerts its influence through diet and even the medications you take on the composition of metabolites that drive countless functions throughout your body’s bloodstream.

But how much does your gut really affect your health? Much more than you would ever assume…

 

The Connection Between Your Gut and Your Blood

Two recent studies conducted in Sweden and America came to strikingly similar conclusions. In both cases, gut microbiomes drove variances in blood metabolites.

After examining the presence of 930 blood metabolites in more than 1,500 patients, researchers from the Institute of Systems Biology (ISB) in Seattle concluded more than 60 percent of those metabolites were tied directly to the gut microbiome, a patient’s genetic makeup or both.

Of that number, 69 percent of those connections were driven solely by the microbiome and an additional 16 percent were controlled by a genetic-microbiome hybrid. Only 15 percent of the metabolites tracked were associated with a patient’s genetic makeup.

Swedish researchers from Lund University and Uppsala University came to similar conclusions, estimating as much as 58 percent of the variances of individual blood metabolites are linked to the microbiome.

Moreover, this team documented more than 546,000 associations between specific gut species and blood metabolites.

 

The Main Takeaway

So, in simple terms, what does this knowledge really mean for our understanding of the gut microbiome and your own health?

For one, understanding the variances between the composition of bacteria in the gut and metabolites in the blood can help scientists find more targeted approaches to health problems, says Dr. Sean Gibbons, an ISB faculty member and study co-author.

Also, these findings suggest that our gut health drives a majority of the metabolites in our blood, and that they can be treated and enhanced by basic lifestyle interventions.

For example, eating a diet rich in dietary fiber can make a huge difference. Just adding one ounce of fiber is all it takes, and it’s doable if you enjoy nutrient-dense foods like lentils, green beans, oats and mushrooms.

Researchers also suggested taking a probiotic could provide a healthy boost to your metabolites.

To the end, be sure that any probiotic you take is formulated with multiple strains of beneficial bacteria from the Bifidobacterium and Lactobacillus families as well as a prebiotic (that feeds the good bacteria in your gut) like EndoMune Advanced Probiotic.

 

Resources

Nature Metabolism

Institute for Systems Biology

Gut Health News

Uppsala University

Nature Communications

ScienceDirect

Illustration of breast exam that includes an illustration of the human gut. Text reads: "Breast Cancer and Your Unbalanced Gut

Breast Cancer and Your Unbalanced Gut Health

Breast Cancer and Your Unbalanced Gut Health

The list of serious health problems associated with an unbalanced gut is growing as researchers discover more links between gut dysbiosis and various forms of cancer.

Some of the more interesting and disturbing findings have come recently from a research team at the University of Virginia’s Department of Microbiology, Immunology and Cancer Biology unit studying the connections between the gut microbiome and breast cancer.

So, why does breast cancer spread in some patients but not all of them?

A new study from Virginia researchers has answered that simple question, concluding alterations in a patient’s gut health influence changes in healthy breast tissue that makes it easier for breast cancer to spread to other parts of the body.

Scientists led by Dr. Melanie Rutkowski found an unhealthy gut reprograms mast cells (immune cells in healthy breast tissue) accumulating in the breast that eventually allows cancer to spread to other organs, according to a study appearing in Cancer Immunology Research.

Based on work with human patients and mice, an unbalanced gut alters breast tissue even before the presence of a tumor, setting the table for a tumor to have the resources it needs to spread cancer cells throughout the body, says Dr. Rutkowski.

Additionally, researchers could calculate the risk for a recurrence in breast cancer merely based on the number of mast cells and collagen, opening the door to develop treatment strategies targeted at prevention.

The need for life-saving alternatives is real. Just 29 percent of women and 22 percent of men survive five years after a metastatic breast cancer diagnosis.

Until those alternatives come, the best cancer-fighting steps you can take to protect your gut and your health are easy ones.

  1. Eat a diet rich in nutrient-dense whole foods and dietary fiber and ditch your Western diet ways.
  2. Incorporate more movement in your life with some consistent exercise. Even walking helps!
  3. Stay on a consistent sleep schedule.
  4. Avoid antibiotics except when you really need them.
  5. Take a daily probiotic with multiple strains of beneficial bacteria, like EndoMune Advanced Probiotic.

Need some help figuring out how to get the most out of a probiotic? Check out our updated guide on the basics of taking a multi-strain probiotic, and learn why the prebiotics contained in probiotics matter, especially when fighting cancer.

 

References

Cancer Immunology Research

UVA Health Newsroom

National Cancer Institute

Click On Detroit

Senior woman gripping wrist. Overlayed text on image reads: "Reduce inflammation with multi-strain probiotics

Reduce Inflammation With Multi-Strain Probiotics

Reduce Inflammation With Multi-Strain Probiotics

If you’ve experienced a cut, low-grade fever or a broken toe, you know what inflammation feels like.

Inflammation is a very necessary signal from your body’s immune system in the form of pain, warmth, swelling or redness that lets you know healing is on the way. Fortunately, much of the inflammation our bodies experience is acute and gets resolved pretty quickly.

However, chronic inflammation is a much more serious problem that can be triggered in the very same ways, but it often doesn’t go away, even after the initial problem gets resolved.

The real challenge, especially for seniors, is preventing chronic inflammation, and there’s many lifestyle modifications you can make to lower your risks.

Adding a multi-strain probiotic and an omega-3 supplement (with vitamin D) every day to your anti-inflammatory to-do list may help too, according to a recent study appearing in Nutrients.

 

Curbing Chronic Inflammation

A team of European scientists were eager to study simple, non-drug ways to curb the effects of inflammaging, a chronic, low-grade form of inflammation that develops as seniors age, increasing their risks of health problems.

Over the course of eight weeks, researchers tracked the health of 76 elderly patients (ages 65-80) who took placebos or a multi-strain probiotic containing Bifidobacterium lactis and Lactobacillus acidophilus, along with an omega-3 supplement (consisting of fish oils and vitamin D).

(These probiotic strains tested in this trial are among the 10 featured in EndoMune Advanced Probiotic for adults.)

The benefit for seniors battling inflammation came from an upward trend in levels of the anti-inflammatory chemical cytokine IL-10 and a big increase in beneficial short-chain fatty acids (SCFAs) among patients taking the multi-strain probiotic/omega-3 combo.

Interestingly, this isn’t the first time we’ve talked about the benefits of fish oil when taken with a multi-strain probiotic like EndoMune, fortified to maintain and protect your immune system by increasing the good bacteria in your gut.

 

Resources

Nutrients

Nutra Ingredients.com

WebMD

Cleveland Clinic

Harvard Health Publishing

Middle aged man holding bag of groceries overstuffed with produce

How Men Can Avoid the Colon Cancer “Diet”

How Men Can Avoid the Colon Cancer “Diet”

There’s no doubt in the world that one of the easiest things you can do to protect your health and avoid serious disease — eating a nutrient-dense diet packed with lots of unprocessed whole foods, fiber and natural sugars — is one of the best things too.

Unfortunately, we see the old adage, You are what you eat!, play out every day in rising mortality rates on a global scale due to poor diets than smoking and car accidents.

A recent study appearing in The BMJ underscores the risk of poor diets, concluding that men raise their risk of developing colon cancer by 29 percent just by eating highly processed foods.

 

Rising Rates of Colon Cancer

You’ve probably read similar reports we have about the rising rates of colon cancer, leading scientists to predict it will become the leading cause of death for patients under age 50 by the end of this decade.

Researchers at Tufts University’s Friedman School of Nutrition Science and Policy already had assumed diet was a major contributor in a colon cancer diagnosis, but who was more vulnerable and why.

Scientists reviewed data from more than 205,000 patients across three large studies that tracked dietary intake along with how often people consumed a list of some 130 foods for more than 25 years.

During that time, men were far more susceptible to colon cancer than women, largely due to eating diets full of highly processed meats, poultry, pork and fish, ready-to-eat meals and sugar-sweetened drinks.

These results led researchers to consider the possibility that other factors could be responsible for rising colon cancer risks among men, like the role food additives play in harming the balance of bacteria in the gut and promoting inflammation.

 

Reduce Your Colon Cancer Risks

Eating a healthier, fiber-rich diet made up of fewer highly processed meats along with incorporating some movement into your daily routine will go a long way toward reducing your colon cancer risks. However, we recommend adding a couple of things to your to-do list.

For one, get screened for colon cancer as soon as you’re able. Although the U.S. Preventative Services Task Force recommended lowering the age for a first screening to age 45 last year, if you have a family history of colon cancer take the initiative and do it sooner.

Also, given what we already know about the health-harming use of antibiotics and their effect on raising your colon cancer risks, we recommend taking a daily probiotic with multiple strains of beneficial bacteria and a proven prebiotic (that feeds the beneficial bacteria in your gut).

You can get the protection you need with the proprietary blend of 10 proven strains of beneficial bacteria from the Lactobacillus and Bifidobacterium families and the prebiotic FOS contained in each serving of EndoMune Advanced Probiotic.

 

Resources

Tufts Now

The BMJ

People

packet of sugar alternatives

Are Sugar Substitutes Safe For Your Gut?

Are Sugar Substitutes Safe For Your Gut?

The challenge for many people trying to lose weight often comes down to the tradeoffs they make along the way.

For example, low-calorie sugar substitutes are some of the most popular tools people use to satisfy their sweet tooth and keep their weight-loss goals on track.

However, we’ve seen plenty of evidence that sugar substitutes like sucralose, saccharine, aspartame and stevia create lots of gut health problems.

Could you be swapping one set of serious health problems for others by using zero-calorie sweeteners?

 

Sugar Substitutes Alter the Microbiome

Israeli researchers from the Weizmann Institute of Science recently showed how a variety of sugar substitutes alter the microbiome negatively, even when consumed briefly in small amounts, according to a study appearing in Cell.

Scientists screened some 1,400 healthy patients before selecting 120 people (ages 18-70) for this project who had one thing in common: Each patient avoided artificially sweetened foods and drinks in their daily life.

Then, patients were divided into groups who consumed prescribed amounts one of four sweeteners (saccharin, sucralose, aspartame or stevia) and two control groups (glucose or no sweetener at all) for two weeks.

Compared to those in the control groups, patients who consumed any sugar substitute experienced unique changes in the composition and functionality of their microbiomes.

Also, patients in the sucralose and saccharin groups had experienced even more significant alterations in how their bodies metabolized these chemicals, a warning sign of metabolic disease, by altering their glucose tolerance.

As one last check, researchers transplanted gut bacteria from 40 “sugar” patients into germ-free mice that had never consumed it to observe any changes. No surprise, the changes in glucose tolerance among mice consistently mirrored those of their human donors.

“These findings reinforce the view of the microbiome as a hub that integrates the signals coming from the human body’s own systems and from external factors such as the food we eat, the medications we take, our lifestyle and physical surroundings,” says lead researcher Dr. Eran Elinav.

 

Losing Weight Safely

Although consuming sugar substitutes in amounts big or small can harm your gut and the way your body breaks down glucose, you still have healthy options that are pretty easy to follow to keep losing weight and protect your gut.

For one, drinking plenty of clean water keeps you hydrated. (Add some flavor to your water with slices of lemon along with a dash of turmeric or cinnamon.)

If you can’t give up your favorite “diet” soft drink, be sure to protect the balance of bacteria in your gut by taking a multi-strain probiotic like EndoMune Advanced Probiotic.

And, if you want some extra help to lose those extra pounds, consider EndoMune Metabolic Rescue, a probiotic uniquely formulated with Bifidobacterium lactis and the prebiotic XOS that promotes a sense of fullness and protects your gut health.

 

References

Cell

Weizmann Institute of Science

Food Navigator-USA.com

Jar of peanut butter with peanuts next to it.

Can Probiotics Help Peanut Allergies

Probiotics: The Gut Solution to Peanut Allergies

Food allergies remain some of the most common and challenging health problems people face throughout their lifetimes.

More than 170 foods have been found to trigger allergic reactions, with peanuts topping the list among children (affecting 1 out of every 50 kids in America) and ranking third among adults (below shellfish and milk).

Avoiding foods containing peanuts can be really tricky, requiring you to pay close attention to food labels and menus. Even with close vigilance, you may still find peanuts as an ingredient in some unusual places, like chili, pizza, sauces, candies, ice creams and even lawn fertilizer.

For people who come in contact with peanuts, either through skin contact or eating them, the possible symptoms can range from the very uncomfortable (diarrhea, skin rash, cramps, swelling) to life-threatening (anaphylaxis).

Researchers at the Murdoch Children’s Research Institute have been testing the use of probiotics as a viable treatment for peanut allergies with much success, as we’ve shared with you previously.

A new study from the Australian-based institute has concluded a sizeable number of children treated with probiotics and oral immunotherapy achieved total remission and were able to eat peanuts safely.

Here’s how…

 

It’s All In The Genes!

Based on her previous work on peanut allergies, Dr. Mimi Tang and her Australian research team discovered the mechanism that facilitates the remission of these immunological problems via activity at the gene level.

For this latest randomized study, 62 children between ages 1-10 received a placebo or a probiotic containing a proprietary strain of Lactobacillus rhamnosus (one of the 10 strains of beneficial bacteria contained in EndoMune Advanced Probiotic) plus oral immunotherapy (the gradual introduction of peanuts) for 18 months.

After this first trial, 74 percent of the patients receiving a probiotic and oral immunotherapy achieved relief from their peanut allergies compared to just 4 percent of the placebo group.

Later on, a follow-up trial found about half of the children treated with oral immunotherapy and probiotics or oral immunotherapy alone achieved total remission and were able to eat peanuts safely.

“What we found was profound differences in network connectivity patterns between children who were allergic and those who were in remission,” says Dr. Tang, an immunologist/allergist and a well-known expert in food oral immunotherapy.

This molecular connectivity and communication triggered changes in allergen-specific Th2 cells (essential components in the development of food allergies) that “turned off” signaling in children whose peanut allergies were in remission.

 

Not So Fast…

While these latest results are great news for people who suffer from peanut allergies (while promoting good gut health), it could take a while before a final, rock-solid protocol to treat food allergies is put in place.

Until then, if you or your child suffer from an allergy to food like peanuts, we strongly recommend discussing any strategies with your doctor first.

 

Resources

Allergy

Murdoch Children’s Research Institute

Cleveland Clinic

Food Allergy Research and Education

Senior african american woman smiling and looking up and away from camera. Overlaid text on image reads "The Aging Gut 101: Healthy Aging, Healthy Gut

The Aging Gut 101

The Aging Gut 101: Healthy Aging, Healthy Gut

“Does my gut age just like the rest of me?”

We get this question a lot, especially from older folks who are starting to understand the connection between the gut and their health in ways that matter directly to them, like maintaining their bones and preserving their cognitive skills.

The simple answer: The composition of bacteria in your gut evolves with time just like your body. Your microbiome develops rapidly from infancy to age 3, stabilizes through middle age, then changes rapidly later in life, according to the National Institute on Aging.

Those changes can be a good thing. In fact, the more your gut bacteria evolves as you age, the better your overall health may be, based on recent research appearing in Nature Metabolism.

Your Evolving Gut

This study compared a wealth of data on human health along with gut microbiome genetic sequencing data on more than 9,000 patients ranging from ages 18-101.

However, the real focus of the research team (led by scientists at the Institute for Systems Biology) was a subset of more than 900 older patients (ages 78-98) to better understand the makeup of their microbiomes and how they matched up with their overall health.

To the good, older adults whose microbiomes kept evolving enjoyed better overall health, as evidenced by lower levels of LDL cholesterol and triglycerides, higher vitamin D levels and more beneficial blood metabolites produced by the gut (including one that reduced inflammation and extended lives in previous animal studies).

Not only did those with more unique microbiomes feel better, they experienced greater overall mobility and could walk faster than their peers whose gut health didn’t change as much with age.

To the bad, patients with less diverse microbiomes took more medications and were nearly twice as likely to die during the course of the study.

Scientists also learned that microbiome uniqueness was more prevalent among women, which may go a long way toward explaining why women often outlive men…

Your Diet Matters

So, what drives microbial evolution and longevity among seniors? The healthiest patients with the most dramatic shifts in their microbiomes experienced steep drops in Bacteroides, a species commonly found in people who eat more processed foods and far less fiber.

When patients eat less fiber, the Bacteroides in their guts have little to eat which can trigger an immune response leading to chronic inflammation and an array of age-related conditions from arthritis to heart disease.

These results certainly mirror previous articles we’ve shared about the many health benefits of dietary fiber, especially if you want to maintain a resilient, healthy gut microbiome that evolves as you age.

How much fiber your body needs every day to maintain optimal health depends on your gender — men need a bit more (31-38 grams) than women (21-25 grams) — and the quality of your diet.

Are You Taking A Probiotic?

If you’re having challenges getting enough fiber, taking a daily probiotic formulated with proven strains of beneficial bacteria and a prebiotic can do a lot of good.

Taking a probiotic with a prebiotic may also reduce low-grade inflammation. This was the key finding in a recent review of studies appearing in Nutrients.

One of the real benefits of taking a probiotic comes from the production of butyrate (short-chain fatty acids created when your gut digests soluble fiber) that reduces chronic low-grade inflammation in your gut.

If you’ve been looking for a good probiotic, find one with multiple strains of beneficial and proven bacteria from the Bifidobacterium and Lactobacillus families plus a prebiotic that feeds the good guys in your gut, like EndoMune Advanced Probiotic.

Resources

National Institute on Aging

Nature Metabolism

New York Times

Gut Microbiota For Health

Nutrients

Nutraingredients Asia

Illustration of a gut, a heart, and a brain all connected by a dotted line. Text: The Gut's connection to stroke

The Gut Connection to Stroke

The Gut Connection to Stroke

Many of you know about the connection between poor diets rich in fats, red meat and processed foods and the cluster of problems that trigger metabolic syndrome.

Conditions such as high blood pressure, elevated blood sugar and cholesterol levels, and extra body weight around the waist are manageable on their own. That is, until they manifest as a group leading to metabolic syndrome.

When they do, your risks of even more serious cardiovascular problems, like stroke, heart disease and type 2 diabetes, escalate dramatically.

Did you know the gut has a direct connection to metabolic syndrome and poor cardiovascular health? This may increase your chances of a severe stroke and other serious health problems afterward?

Here’s how…

 

The TMAO Problem

When we consume foods or drinks high in choline (red meat, eggs, high-fat dairy products) and L-carnitine (red meat and some energy drinks), our gut bacteria breaks them down into trimethylamine (TMA).

Then, TMA is converted by the liver to TMAO (trimethylene N-oxide), a metabolite that has been linked to the narrowing or obstruction of arteries and increases in blood clots, leading to a higher risk of heart attack and stroke.

Researchers at the Cleveland Clinic have spent more than a decade examining how the gut microbiome affects our cardiovascular health with findings that have yielded significant insights about TMAO.

A recent Cleveland Clinic study determined the dual presence of elevated TMAO and choline was enough to produce, not only strokes of greater size and severity, but more challenging post-stroke functional impairments.

Scientists came to these conclusions after transplanting fecal samples from human patients with high or low levels of TMAO into germ-free mice.

Over the course of the study, animals receiving fecal transplants with higher levels of TMAO had more of it in their bloodstreams and experienced more extensive brain damage in multiple stroke models as well as greater post-stroke motor and cognitive deficits.

What’s more, the presence of bacteria containing CutC, a key enzyme related to choline that drives TMAO production in the gut, was enough to more than double stroke severity and worsened functional outcomes by as much as 30 percent.

 

What You Can Do About It

Based on our previous article about the problems associated with the Paleo Diet, a diet focused on more meat or Western diet staples like highly processed foods, creates the ideal environment for bad gut bacteria that generate unhealthy amounts of TMAO and lessen the impact of beneficial bacteria.

Fortunately, there’s some easy steps you can take to protect your gut and cardiovascular health from harm. For starters, increasing your intake of dietary fiber by just 1 ounce (30 grams) in your diet can help you lose weight and reduce your cardio risks.

Besides adding more fiber to your diet, taking a probiotic fortified with multiple strains of beneficial and proven bacteria from the Lactobacillus and Bifidobacterium families like EndoMune Advanced Probiotic, can do a great deal of good to promote the natural fermentation process that protects your gut.

 

References

Cell Host & Microbe

Cleveland Clinic/Consult QD

Cleveland HeartLab

SelfDecode

Mayo Clinic

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