gut-brain axis

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The Probiotic Treatment For Anxiety

Experiencing anxiety is more common than you think.

Think about the last time…

  • You went to the hospital for a medical test.
  • You gave a talk in front of a group of people, including some you didn’t know.
  • You had to make a decision about a problem with no clear-cut solutions.

Any one of those situations are potentially nerve-wracking, but they tend to pass pretty quickly.

But, if you’re frequently avoiding situations that could create excessive worries, you may be dealing with an anxiety disorder, and that may be a real problem.

Many people — including health providers — turn to antidepressants like fluoxetine (Prozac) or escitalopram (Lexapro) or benzodiazepines like diazepam (Valium) or alprazolam (Xanax) to alleviate anxiety.

However, taking drugs (especially benzodiazepines) may create even more health challenges down the road.

Did you know taking better care of your gut health may be just as beneficial in treating anxiety?

The gut health solution

As you know, there’s plenty of evidence supporting the gut-brain axis, the connection linking your intestines, brain and emotions.

A new report by Chinese researchers, recently published in the journal General Psychiatry, reviewed a batch of studies, finding 21 studies that examined boosting gut health as a means to treat anxiety.

The success rate was excellent. Eleven of the 21 studies discovered improvements in anxiety symptoms by treating a patient’s gut health.

Interestingly, the results were split nearly down the middle with five studies finding success with probiotics and six studies treating patients through non-probiotic means such dietary interventions.

Of course, there were limitations, as most of the patients participating in these students were having problems with an array of health issues. Among the six studies that did examine gut health interventions to treat anxiety, four showed positive results.

Listed among the non-probiotic interventions was the use of short-chain fructo-oligosaccharides (FOS), a natural prebiotic made from plant sugars and non-digestible starches. Additionally, FOS is one of the key ingredients in EndoMune Advanced Probiotic.

It’s important to remember prebiotics feed the good guys in your gut, but really do a lot more good when they’re part of an effective probiotic like EndoMune.

Drug-free treatments for anxiety

There are many things you can do treat anxiety that don’t require taking a drug:

All of these things have one important thing in common: Not only do they improve your overall health, they do wonders for your gut.

In addition to working on these healthier habits, be sure to take an effective probiotic like EndoMune, with multiple strains of beneficial bacteria, plus a prebiotic.

Illustration of probiotics at a cellular level.

The Multi-Species Advantage For Your Brain and Mood

The human gut is one very diverse sector of the human body.

More than 1,000 unique species of gut bacteria have been identified by medical investigators so far. That doesn’t include 2,000 more species recently discovered in populations of people living in Asia, Africa and South America.

What we do know (for the moment): Experts believe about 150-170 species live in the human gut at any time.

So, when we talk about the value of treating health problems like constipation, C. diff infections and even colon cancer, probiotics that contain multiple species of beneficial bacteria have been proven to do much more good than single-species products or even “probiotic” foods.

The gut-brain axis difference

The very same can be said for your gut-brain axis, the vital connection that links your brain, emotions and intestines, according to recent research appearing in the medical journal, Frontiers in Psychiatry.

For this study, researchers at the University of Verona (Italy) tracked the progress of 38 healthy volunteers (ages 18-35) who took either a placebo or multi-species probiotic including Lactobacillus rhamnosus, Lactobacillus plantarum and Bifidobacterium longum for six weeks.

(This trio is part of the 10 species of beneficial bacteria contained in every bottle of EndoMune Advanced Probiotic.)

Scientists monitored the mood, mental health and sleep quality of patients before the study began, then in three-week intervals during and after the study concluded.

The group who took probiotics reported significant improvements in fatigue, mood and anger, better acceptance (a marker of decreased depression) and enhanced sleep quality.

In fact, scientists were surprised to find benefits from taking multi-species probiotics lingered at least three weeks after the test subjects stopped taking them.

Those positive results for multi-strain probiotics aren’t surprising at all, given that the gut produces neurotransmitter chemicals like serotonin (governing your mood) and gamma-aminobutyric acid (GABA) (controlling anxiety and fear).

Getting good sleep matters too

A healthy gut helps you get the right amount of sleep too. Not only does it promote better sleep, good gut health eases disruptions in your body’s circadian rhythms — governing your 24-hour biological clock — particularly when jet lag can be a factor due to traveling across multiple time zones in short periods of time.

Another gut-healthy way to promote restful sleep: Be sure you’re eating enough prebiotics, the natural, non-digestible carbohydrates/plant fiber contained in whole foods like almonds, jicama, artichokes, onions, leeks, apples and bananas.

If you’re not getting enough whole foods, that’s just one more important reason to take a daily probiotic like Endomune, that features fructo-oligosaccharides (FOS), a natural prebiotic made from plant sugars.

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The Gut-Brain Link to Depression and Obesity

It wasn’t long ago that conventional medicine debated the existence of the gut-brain axis, the connection that links your emotions, intestines and brain.

The medical community couldn’t dispute it for long, however, given that about 90 percent of serotonin, a chemical that sends messages from one side of the brain to the other, is produced in the human gut.

Obesity and diabetes are serious conditions that harm many parts of your health, including your gut. (Remember, gut health problems could be a warning sign of type 1 diabetes?)

Eating a high-fat diet, a direct contributor to obesity and diabetes, creates greater emotional problems and direct shifts in the makeup of bacteria in the gut too, according to findings from the Joslin Research Center (affiliated with Harvard Medical School).

In their work with mice, Joslin researchers had long studied the damage done by diabetes, obesity and other metabolic health problems in their work with mice fed high-fat diets.

One variable stood out in their previous research: Obese mice that had been fed high-fat diets showed far more signs of emotional problems (depression, anxiety and obsessive behaviors) than animals fed healthier diets.

For their newest study, researchers took a different approach by giving mice behavioral tests commonly used to screen drugs for depression and anxiety. They learned mice that were fed high-fat diets experienced greater amounts of depression and anxiety.

However, when scientists took steps to change the gut health makeup of obese mice by giving them antibiotics their emotional health improved.

Taking that gut bacteria shift one step further, Joslin research also discovered the gut microbiomes of obese mice triggered emotional problems when they were transplanted in germ-free mice. And other germ-free mice that received gut bacteria from obese mice given antibiotics showed no signs of emotional problems either.

Where the gut-brain link really came into play was when researchers examined parts of the brain that govern metabolism and emotions, according to Dr. C. Ronald Kahn, Chief Academic Officer who leads the Section on Integrative Physiology and Metabolism at Joslin.

Like other tissues, these areas of the brain became insulin-resistant in test animals fed high-fat diets and this resistance was mediated partly by their microbiomes, Dr. Kahn said.

The Joslin team also found alterations in the gut health of mice were linked to the production of some chemicals that send signals across the brain too.

Now, scientists are studying specific populations of bacteria involved in the gut-brain axis that may govern this process, with an eye on creating healthier metabolic profiles in the brain.

Interestingly, Dr. Kahn points out the problems of using antibiotics as “blunt tools that change many bacteria in very dramatic ways.”

“Going forward, we want to get a more sophisticated understanding about which bacteria contribute to insulin resistance in the brain and other tissues. If we could modify those bacteria, either by putting in more beneficial bacteria or reducing the number of harmful bacteria, that might be a way to see improved behavior.”

Fortunately, there’s a growing body of evidence that shows probiotics like EndoMune Advance Probiotic may be a safe and proven tool for treating behavioral issues among mice and humans and provide some extra help to fight obesity too.

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Question What You Read Everywhere!

If you follow my blog and keep up with the news, you’ve heard about a pair of recent studies published in the medical journal, Cell, that found probiotics may have very limited value.

Unfortunately, the mainstream media — seemingly everyone from CBS News to Forbes — jumped on the bandwagon to dispute the value of probiotics without looking at their considerable and proven benefits over time, many of which we’ve discussed here.

Since you have some questions and concerns about these reports, we have some answers.

What do the studies say?

Study one examined how well a generic probiotic with 11 strains of bacteria could colonize the intestinal lining when given to 25 healthy adults, as determined with a colonoscope taking specimens from the mucosa, versus a placebo.

This approach differs from most previous studies in which probiotics were measured in stools. Their justification was to determine if the generic probiotics you find at most supermarkets “colonize the gastrointestinal tract like they’re supposed to, and then whether these probiotics are having any impact on the human host.”

Study two investigated whether patients should be taking a probiotic when they were prescribed an antibiotic to prevent antibiotic-associated diarrhea.

Twenty-one healthy patients were divided into three groups: Seven took an antibiotic, six more were given an antibiotic and the same generic probiotic from the first study and the rest received an antibiotic and pills containing fecal samples from their own microbiome.

What were the results?

In study one, the generic probiotic bacteria were found in the stools of each patient, and only in the lining of the colon of a few patients. This finding led scientists to conclude that, if probiotic bacteria weren’t found in the colon, they’re not beneficial. It also explains why many stories reported probiotics were ‘’useless.”

The results of study two were a bit more complicated:

  • The microbiomes of patients who received just an antibiotic returned to their healthy composition after 21 days.
  • Patients given fecal transplants experienced a normal intestinal microbiome within days after stopping the antibiotic.
  • Among patients treated with a generic probiotic, their microbiomes did not return to their original composition even five months later.

Problems with both studies

Now that you’ve had a chance to review both studies, it’s easier to see why taking these results at face value is tricky.

The problem with study one that examined the use of a generic probiotic was pretty straight-forward. These generic probiotics were given to healthy people with normal microbiomes, so the beneficial bacteria wouldn’t find a place in the lining of the colon to colonize.

In fact, the immune system of the intestines and existing microbiome would prevent it!

Studies have shown when patients struggle with gut health problems like irritable bowel syndrome (IBS), taking a good probiotic can treat their symptoms and rebalance their microbiomes. So, probiotics aren’t “useless!”

In study two, because patients treated with a generic probiotic after receiving an antibiotic didn’t return to normal right away, researchers assumed the probiotic might cause ”harm” by increasing their risk of intestinal disorders. Moreover, researchers suggested patients “personalized probiotics” in the form of fecal transplants might lessen any risks.

Unfortunately, this phase of the study set up patients for more health problems like diarrhea down the road, merely by giving them antibiotics.

Plus, antibiotics change the composition and balance of bacteria in the gut, which may increase the activity of enzymes that trigger a faster absorption of carbohydrates, leaving you more vulnerable to obesity and diabetes.

Remember those extra carbs and fats feed poor dietary habits that disrupt your gut-brain axis, the biological connection that links your intestines, brain and emotions.

One more variable this research team didn’t consider in either study: The contribution of prebiotics, the non-digestible starches that feed the bacteria in your gut contained in a lot of probiotics, including EndoMune Advanced ProbioticEndoMune Junior Probiotic and EndoMune Metabolic Rescue.

Prebiotics have been shown to offer a number of health benefits connected with probiotics, like improving your sleep and giving your body some extra protection from type 2 diabetes.

Also, I have to take issue with the use of fecal transplants to engineer the results of this study. Fecal transplants may have performed better among three options in this second study, but going this route isn’t without its risks, especially if you’re receiving fecal matter from another donor.

In one 2015 report, a patient was successfully treated for a recurring C. diff infection with a fecal transplant from an overweight donor (her daughter) only to gain 34 pounds in just 16 months.

In other cases, people who have tried “do-it-yourself” fecal transplants from donors have suffered brand new health problems they never expected from people who seemed to be very healthy, but were carriers of germs they could pass on to others.

I cannot stress enough that using these results from both studies to imply that probiotics in many cases are “useless” or “harmful” just isn’t accurate.

As a physician specializing in gastroenterology, I’ve seen firsthand how the use of probiotics has changed the lives of patients suffering from simple problems like constipation and hard-to-treat ones like IBS. Also, patients who are on a strong course of antibiotics may avoid the risks of experiencing life-threating infections just by taking a probiotic too.

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Gut Health May Play a Role in PTSD

For a long time, many people have associated posttraumatic stress disorder (PTSD) — a condition that develops in some who have experienced a dangerous, shocking or frightening event — with soldiers and police officers who deal with life and death situations on a daily basis.

Some experts who understand it intimately, however, believe PTSD is a public health problem that’s triggered by painful events other than war-related experiences.

That wider perception of PTSD symptoms has evolved over the years to include a broader scope of direct traumas — like experiencing a serious car accident, life-threatening illness, violent physical assault or other traumatic events — as well as indirect ones (hearing about the death of a loved one).

By the numbers, 60 percent of all men and half of all women in America will experience at least one traumatic event and roughly 8 percent of all Americans will face PTSD during their lifetimes, according to the National Center for PTSD.

Now that modern science better understands the gut-brain axis (the connection that links your intestines, emotions and brain) more fully, it’s not at all surprising to learn the balance of bacteria in your gut may predict if you’ll experience PTSD or not, according to a study appearing in Psychosomatic Medicine.

The gut bacteria drop-off

Researchers at the University of Colorado and Stellenbosch University (South Africa) teamed up to compare the microbiomes of 18 patients with PTSD with a control group of 12 patients who experienced significant trauma but not PTSD to identify any abnormalities in the gut.

PTSD patients had dramatically lower levels of three bacterial species (Actinobacteria, Verrucomicrobia and Lentisphaerae) compared to the control group. Additionally, patients who experienced childhood trauma had lower levels of two species (Actinobacteria and Verrucomicrobia).

This second finding interests and worries researchers because people who experience childhood trauma are at a higher risk of facing PTSD later in their lives. In fact, these changes in gut health balance may have happened much earlier in response to childhood trauma, says lead researcher Dr. Stefanie Malan-Muller, according to a press release.

Another problem with this gut bacteria drop-off: All three are responsible for regulating the body’s immune system, and inflammatory markers soon after a traumatic event are an indicator that predicts the development of PTSD later on, says Dr. Malan-Muller.

Hopefully, more research will determine if this specific fall in gut bacteria makes patients more vulnerable to PTSD or if it occurs as a result of PTSD.

Could probiotics be used to treat PTSD? Researchers at the University of Colorado were impressed by the results of their 2016 study on preventing a PTSD-like syndrome in mice by adding beneficial bacteria to their tiny microbiomes.

Currently, this team of researchers is studying the key factors that lead to the development of PTSD in hopes their findings can lead to better treatments. A potential treatment the team is looking is one that alters microbiome with the use of probiotics containing a strain of Lactobacillus (one of the families of beneficial bacteria contained in EndoMune Advanced Probiotic and EndoMune Junior Probiotic for kids) and prebiotics.

Stay tuned to the EndoMune blog for more news about PTSD and other health information that affects your gut health.

Can Yogurt Treat Depression?

Yogurt is a delicious and nutritional treat people often confuse as a remedy for all sorts of health conditions (often with the sneaky help of science).

But can yogurt treat depression, one of the most pervasive, frustrating and common health problems affecting more than 16 million adults in America annually?

A recent study appearing in Scientific Reports concluded feeding mice a proprietary strain of Lactobacillus reuteri in yogurt made from live cultures was enough on its own to reverse depressive symptoms in stressed out mice.

A team of scientists at the University of Virginia’s School of Medicine came to that finding after studying the gut health of tiny mice and discovering the depletion of Lactobacillus reuteri triggered the onset of depression.

To take it a step further, that loss of Lactobacillus reuteri was responsible for spiking levels of kynurenine (a metabolite in blood) that bring on depressive symptoms. Once mice were fed Lactobacillus reuteri with their food, however, their stress levels returned to nearly normal, scientists said.

This research does represent evidence that the gut-brain axis – the link between your brain, emotions and intestines – is very much a reality, and maintaining a healthy balance among all three is critical for good physical and mental health.

University of Virginia scientists were so pleased with these results on mice, they plan to turn their attention to human subjects, specifically with multiple sclerosis patients who struggle with depression too.

However, one probiotic strain may not be enough to do the trick. Other studies have found probiotics formulated with Bifidobacterium longum may have a similar beneficial effect on treating depression.

What’s more, there’s no guarantees the yogurt you’ll find in a grocery store will contain exactly the right amounts or combinations of beneficial bacteria that make much of a difference on balancing your emotions.

But, there is growing evidence that a probiotic containing multiple strains of beneficial bacteria – think EndoMune Advanced Probiotic — may be a more effective solution for treating depression and a safer one given all of the side effects associated with antidepressants.

Smarter Babies, Better Gut Health

For the longest time, we’ve discussed the connection between the brain and gut, better known as the gut-brain axis, and how it affects an array of human health variables from emotions to protecting your baby’s brain.

That connection may also be responsible for higher levels of cognitive development in young babies, depending on the balance of beneficial bacteria in the gut, according to research featured recently in Biological Psychiatry.

Smelly diapers

To assess the relationship between the gut and brain development, researchers at the University of North Carolina’s (UNC) School of Medicine studied fecal samples from 1-year-old babies. Those samples were analyzed then separated into one of three microbial communities.

A year later, that same group of infants was given a series of cognitive tests that measured their language, perception and motor skills.

Overall, babies with higher concentrations of the Bacteroides bacterial genus did the best on cognitive tests. Interestingly, babies with more diverse gut microbiomes didn’t perform as well, a big surprise to UNC scientists.

“We had originally predicted that children with highly diverse microbiomes would perform better – since other studies have shown that low diversity in infancy is associated with negative health outcomes, including type 1 diabetes and asthma,” says Dr. Rebecca Knickmeyer, a member of UNC’s Department of Psychiatry, according to a press release.

“Our work suggests that an ‘optimal’ microbiome for cognitive and psychiatric outcomes may be different than an ‘optimal’ microbiome for other outcomes.”

Gut-brain communication

Another interesting aspect of this study is the realization that the guts and the developing brains of babies may be communicating in very unique ways we’re just learning about every day, Dr. Knickmeyer says.

“That’s something that we are working on now, so we’re looking at some signaling pathways that might be involved. Another possibility is that the bacterial community is acting as a proxy for some other process that influences brain development – for example, variation in certain dietary nutrients.”

Another huge takeaway from this study in measuring the microbiomes of infants: Adult-like gut microbiome communities emerging at such an early age, implying that the ideal age in which to intervene would happen before age 1, says UNC grad student Alexander Carlson.

“Big picture: these results suggest you may be able to guide the development of the microbiome to optimize cognitive development or reduce the risk for disorders like autism which can include problems with cognition and language,” says Dr. Knickmeyer.

Although researchers were hesitant to speculate how probiotics may play a role, a severe imbalance of gut bacteria — specifically Lactobacillus reuteri — may be a trigger for autism, based on a recent study conducted at the Baylor College of Medicine.

These deficits, along with the exploding growth of babies being delivered via Cesarean section in America, puts the health of our most vulnerable at risk from the very beginning of their lives.

A targeted, non-drug solution like a probiotic, like EndoMune Junior Probiotic, may be a safe way to promote better gut health and smarter brains.

 

Probiotics: A drug-free way to treat Alzheimer’s

Alzheimer’s disease is one of the most devastating health problems facing America today. Not only does this mind-robbing condition affect more than 5 million Americans today, with the Baby Boomer generation heading to retirement, that number is expected to triple by 2050.

Although there is no cure for Alzheimer’s, just a handful of FDA-approved drugs relieve symptoms, but only for the short-term. What’s more, they come with an array of side effects, including headaches, nausea, weight loss, diarrhea and constipation.

Fortunately, modern medicine has begun to embrace the gut-brain axis — the connection that links your brain to your intestines and emotions. Over time, probiotics have proven their value as a non-drug tool ideally equipped to maintain that important balance, and treat problems like depression.

One day very soon, neurologists may be using probiotics to treat Alzheimer’s, based on a recent clinical trial featured in Frontiers in Aging Neuroscience.

 

Neurological testing

Over the course of the 12-week, double-blind clinical trial, Iranian researchers split 52 Alzheimer’s patients (between ages 60-95) into two groups. One received 200 milliliters of milk enriched with three strains of Lactobacillus (acidophilus, casei and fermentum) and Bifidobacterium bifidum, while a control group was given milk without beneficial bacteria.

(Lactobacillus acidophilus and Lactobacillus casei and Bifidobacterium bifidum are three important ingredients of EndoMune Advanced Probiotic.)

At the beginning and end of the trial, blood samples were taken and all patients were given Mini-Mental State Exams (MMSEs) that measured their cognitive ability on specific tasks like remembering dates, copying pictures, counting backwards and naming objects.

No surprise, patients who received the probiotic mixture improved on their previous MMSE results after 12 weeks, while those in the control group had lower scores.

Patients in the probiotic group also benefitted in other measurable ways, with lower levels of trigylcerides, high-sensitivity C-Reactive Protein (hs-CRP) and Very Low Density Lipoproteins (VLDL) as well as drops in two common measures used to gauge insulin resistance and the production of insulin in the pancreas.

“These findings indicate that change in the metabolic adjustments might be a mechanism by which probiotics affect Alzheimer’s and possibly other neurological disorders,” said senior study author Dr. Mahmoud Salami, according to a press release.

 

Multi-species power

Arguably, the real benefits Alzheimer’s patients received in improved cognitive skills and healthier blood levels may stem from the multiple species of bacteria, not just one.

In fact, it’s possible giving Alzheimer’s patients a multi-species probiotic like EndoMune Advanced Probiotic with 10 proven strains of bacteria every day may have yielded even greater results.

The gut-brain axis even works between mice and men

The importance of a healthy gut-brain axis — the connection that links your brain, intestines and emotions — is critical to protect your cognitive and physical well-being.

That connection seems pretty clear, considering as much as 90 percent of your body’s serotonin, a chemical neurotransmitter that sends message from one part of your brain to another, may be produced in your gut.

A recent study appearing in Science Translational Medicine takes the gut-brain axis connection to the next level, literally between mice and men, with the help of fecal transplants.

IBS and the gut-brain axis

Curious about the effect irritable bowel syndrome (IBS) has on behavior and intestinal health, researchers from McMaster University and the University of Waterloo took an unconventional approach: Transplanting fecal samples from eight patients suffering from IBS with diarrhea for at least two years and five healthy people into germ-free mice.

Three weeks later, compared to mice that received healthy samples, animals that were given IBS-laced transplants experienced increased gut permeability, low-grade inflammation and faster gastrointestinal transit (how long it takes food to travel from the stomach and through the intestine).

Then, scientists tested anxiety-associated behaviors by measuring the time mice spent in the dark and how long it took them to step down from a platform to explore their environments, according to The Scientist.

Mice that were given fecal samples from human IBS patients who reported anxieties experienced similar emotional difficulties, compared to animals given fecal samples from healthy patients and those with IBS who reported no problems with anxieties.

Probiotics to the rescue

Researcher Dr. Giada De Palma called these findings a landmark “because it moves the field beyond a simple association and toward evidence that changes in the microbiota impact both intestinal and behavioral responses in IBS.”

These results also offer more evidence that human gut health may play a larger role in the range of brain disorders ranging from the emotional (mood or anxieties) to more serious problems, like multiple sclerosis, Parkinson’s disease and autism, according to a press release.

The good news: Scientists believe treatments such as probiotics and prebiotics could be beneficial in treating, not only the physical aspects of IBS but the behavioral issues associated with it too.

Protecting the health of your gut by taking a probiotic like EndoMune Advanced Probiotic is certainly much safer and more effective than taking a drug like mesalazine that merely treats symptoms but not the root cause of IBS: Restoring the balance of beneficial bacteria in the gut.

gut brain

What you eat may harm your gut-brain axis

There may be a problem with your gut-brain axis — the biological connection linking the gut, emotions and brain as one — when eating a diet rich in fats and sugars. These chemicals may cause shifts in mood and cognitive behaviors.

A recent study by Oregon State University (OSU) featured in the medical journal Neuroscience, linking gut health changes caused by following poor diets to serious problems related to cognitive flexibility, the ability to adapt quickly to new and unexpected situations.

“The impairment of cognitive flexibility in this study was pretty strong,” says Dr. Kathy Magnusson of the Linus Pauling Institute at OSU in a press release. “Think about driving home on a route that’s very familiar to you, something you’re used to doing. Then one day that road is closed and you suddenly have to find a new way home.”

Researchers came to that conclusion after feeding mice either high-fat or high-sugar diets, then monitoring their physical and mental performances with an array of physical tests alongside their gut health.

Compared to mice that ate a normal diet, animals that were prescribed high-fat or high-sugar diets began to perform poorly on physical tests after only four weeks. The lack of cognitive flexibility stood out to researchers as one of the most obvious problems.

Young mice with physically stronger and healthier bodies were used in the study because they had more dynamic biological systems. In theory, the stronger mice could better resist the effects of a poor diet, Magnusson says.

On its own merit, the study provided more evidence of how Western diets — high in saturated fats, carbohydrates, refined sugars, processed foods and red meat — forced the gut to adapt by reducing the diversity of bacteria, leaving our bodies vulnerable to many diseases, most of which are preventable.

“We’ve known for a while, too much fat and sugar are not good for you,” Magnusson says. “This work suggests fat and sugar are altering your healthy bacterial systems, and it is one of the reasons those foods aren’t good for you. It’s not just the food that could be influencing your brain, but an interaction between the food and microbial changes.”

One easy way to give your gut microbiota a healthy, natural boost and assist in preventing damage to your gut-brain axis is to take a probiotic with multiple species of beneficial bacteria. These bacteria can treat a variety of conditions related to your gut health.

Unlike many probiotics you’ll find at your health food shop or grocery store, EndoMune Advanced Probiotic contains 10 strains of beneficial bacteria, plus the prebiotic fructooligosaccharide that feeds the good gut bacteria already living in your gut.

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