Probiotic Research

a few pills next to a thermometer

Can Probiotics Reduce the Need for Antibiotics?

If you follow our blog regularly, you’re very aware of the many problems associated with antibiotics.

Patients have leaned on antibiotics so much over the years as go-to drugs to feel better in a hurry that doctors have tended to over-prescribe them.

All too often, doctors will give in to their patients, even for relatively minor health problems caused by viruses (colds, bronchitis and sore throats) that don’t respond to antibiotics in the first place or bacterial infections (many ear and sinus infections) that often aren’t necessary.

Every year, some 47 million prescriptions written for antibiotics are completely unnecessary, according to the CDC. At least half of the antibiotic prescriptions written for bacterial infections are unwarranted too.

This excess use has created an environment in which antibiotic resistance has become far too common. At least 2 million Americans are infected by antibiotic-resistant bacteria annually and some 23,000 will die from exposure to infections, including superbugs like Clostridium difficile (C. diff).

That’s only about 75 years removed from the introduction of penicillin, the first commercially available antibiotic during World War II, in 1943, and a drug that was discovered almost by accident.

However, the tide may be starting to turn away from the excessive use of antibiotics, thanks to the timely use of probiotics, according to a recent report published in the European Journal of Public Health.

Based on a review of a dozen studies, researchers from the U.S. Netherlands and U.K. discovered children and babies were 29 percent less likely to be prescribed antibiotics if they were taking a daily probiotic.

Even more encouraging, a second look at studies that researchers judged to be of the highest quality saw those numbers of probiotic-protected children jump to 53 percent.

“More studies are needed in all ages, and particularly in the elderly, to see if sustained probiotic use is connected to an overall reduction in antibiotic prescriptions. If so, this could potentially have a huge impact on the use of probiotics in general medicine and consumers in general,” says Dr. Sarah King, lead author of the study.

Not surprisingly, the probiotics children were taking in these studies contained strains of Bifidobacterium and Lactobacillus, some of the very same ones in EndoMune Jr. and EndoMune Advanced Probiotic.

Even if you or your family need to take antibiotics when you’re sick, it’s critical to recognize how these drugs can shift the balance of beneficial bacteria in your gut and affect your recovery.

If you’re unsure how to maximize the benefits of taking a probiotic when prescribed an antibiotic, I urge you to review my recently updated and very easy-to-follow probiotic protocol.

Also, check with your doctor before taking a probiotic if you have any concerns, especially if you’re taking immunosuppressant drugs or antifungal products for a health condition.

woman having trouble getting out of bed

Is Chronic Fatigue Syndrome a gut issue?

Chronic fatigue syndrome (CFS) is a very frightening and complicated disorder. Defined as severe exhaustion that can’t be relieved by rest, this condition has frustrated modern medicine for a long time.

Also known as myalgic encephalomyelitis (ME/CFS), this disease has no real triggers or underlying conditions, and diagnosing it requires a lot of time and testing. Although anyone can have CFS, women are far more likely to suffer from it than men, most commonly in their middle years.

Its symptoms run the gamut, from extreme fatigue lasting more than a day and unexplained joint or muscle pain to enlarged lymph nodes, headaches, poor sleep and even irritable bowel syndrome (IBS).

While CFS is a condition with very few connections, research teams at Columbia and Cornell Universities have found important markers that link it to the human gut.

83 percent accurate

The discovery that connects chronic fatigue syndrome to the human gut was a welcome confirmation to Cornell researchers that its origins were definitely not psychological.

“Our work demonstrates that the gut bacterial microbiome in ME/CFS patients isn’t normal, perhaps leading to gastrointestinal and inflammatory symptoms in victims of the disease,” says Dr. Maureen Hanson, senior author of the study, according to a press release. “Furthermore, our detection of a biological abnormality provides further evidence against the ridiculous concept that the disease is psychological in origin.”

For the record, the Cornell study compared blood and stool samples from 48 CFS patients to 39 health controls. The links to a gut health connection were obvious.

Chronic fatigue patients had less gut bacteria diversity and their blood samples showed signs of inflammation linked to leaky gut. Stool samples also found markers for ulcerative colitis and Crohn’s disease, even more serious gut problems.

Moreover, scientists were able to detect which patients were battling CFS based on microbiome testing with 83 percent accuracy.

Gut imbalances affect severity

Mirroring the Cornell findings, Columbia researchers also found bacterial imbalances – too much of some bacterial species including Faecalibacterium – in the fecal samples of the 50 chronic fatigue syndrome patients they examined (versus an equal number of healthy ones), according to the study appearing in Microbiome.

These imbalances varied depending on whether CFS patients were also suffering from IBS or not (21 of the 50 patients did have IBS). Also, depending on which bacteria imbalance chronic fatigue syndrome patients had and the metabolic pathways affected, the severity of their symptoms differed too.

“Individuals with ME/CFS have a distinct mix of gut bacteria and related metabolic disturbances that may influence the severity of their disease,” says Columbia researcher Dorottya Nagy-Szakal, according to a press release.

Probiotic success

Despite all of the attention paid by Columbia and Cornell researchers, a few scientists already had an eye on the intersection of gut health and chronic fatigue syndrome.

In fact, a systemic review of studies appearing very recently in Beneficial Microbes cited studies that showed how using probiotics may be effective in treating CFS and fibromyalgia.

(Both studies cited in this review used proprietary strains of Lactobacillus and Bifidobacterium, the two building blocks of EndoMune Advanced Probiotic.)

Based on these results, it seems more likely probiotics could become part of a more comprehensive treatment plan for chronic fatigue syndrome. 

“If we have a better idea of what is going on with these gut microbes and patients, maybe clinicians could consider changing diets using prebiotics such as dietary fibers or probiotics to treat the disease,” says Ludovic Giloteaux, a researcher in the Department of Molecular Biology and Genetics at Cornell University.

Probiotics: A drug-free way to treat Alzheimer’s

Alzheimer’s disease is one of the most devastating health problems facing America today. Not only does this mind-robbing condition affect more than 5 million Americans today, with the Baby Boomer generation heading to retirement, that number is expected to triple by 2050.

Although there is no cure for Alzheimer’s, just a handful of FDA-approved drugs relieve symptoms, but only for the short-term. What’s more, they come with an array of side effects, including headaches, nausea, weight loss, diarrhea and constipation.

Fortunately, modern medicine has begun to embrace the gut-brain axis — the connection that links your brain to your intestines and emotions. Over time, probiotics have proven their value as a non-drug tool ideally equipped to maintain that important balance, and treat problems like depression.

One day very soon, neurologists may be using probiotics to treat Alzheimer’s, based on a recent clinical trial featured in Frontiers in Aging Neuroscience.

 

Neurological testing

Over the course of the 12-week, double-blind clinical trial, Iranian researchers split 52 Alzheimer’s patients (between ages 60-95) into two groups. One received 200 milliliters of milk enriched with three strains of Lactobacillus (acidophilus, casei and fermentum) and Bifidobacterium bifidum, while a control group was given milk without beneficial bacteria.

(Lactobacillus acidophilus and Lactobacillus casei and Bifidobacterium bifidum are three important ingredients of EndoMune Advanced Probiotic.)

At the beginning and end of the trial, blood samples were taken and all patients were given Mini-Mental State Exams (MMSEs) that measured their cognitive ability on specific tasks like remembering dates, copying pictures, counting backwards and naming objects.

No surprise, patients who received the probiotic mixture improved on their previous MMSE results after 12 weeks, while those in the control group had lower scores.

Patients in the probiotic group also benefitted in other measurable ways, with lower levels of trigylcerides, high-sensitivity C-Reactive Protein (hs-CRP) and Very Low Density Lipoproteins (VLDL) as well as drops in two common measures used to gauge insulin resistance and the production of insulin in the pancreas.

“These findings indicate that change in the metabolic adjustments might be a mechanism by which probiotics affect Alzheimer’s and possibly other neurological disorders,” said senior study author Dr. Mahmoud Salami, according to a press release.

 

Multi-species power

Arguably, the real benefits Alzheimer’s patients received in improved cognitive skills and healthier blood levels may stem from the multiple species of bacteria, not just one.

In fact, it’s possible giving Alzheimer’s patients a multi-species probiotic like EndoMune Advanced Probiotic with 10 proven strains of bacteria every day may have yielded even greater results.

Probiotics: Can they replace migraine medication?

Anyone who experiences migraines on a regular basis knows how painful they can be, not to mention the harrowing side effects — vomiting, nausea, blurred vision and sensitivity to light and sound — that come with them.

Some 12 percent of all Americans suffer from migraines, conditions that can last for several days and are three times more common among women than men.

As our understanding of the human microbiome expands, science is discovering new connections that link the microbes in our bodies to all sorts of health conditions, even migraines, according to a recent study in MSystems (an open access journal published by the American Society For Microbiology).

The nitrate trigger

To understand the relation between migraines and the microbiome, researchers at the University of California San Diego School of Medicine discovered a link in nitrates, common food additives used to preserve cured meats — think hot dogs — that are also found naturally in vegetables and in some medicines (heart drugs) and wines.

First, bacterial gene sequencing was used to uncover differences in 172 oral samples and some 2,000 fecal samples from healthy donors supplied by the American Gut Project.

This initial sequencing process found differing amounts of bacterial species based on whether donors suffered from migraines or not, yet the bacterial composition of both groups varied little.

The real breakthrough came when scientists used PICRUSt, a bioinformatics software tool, to analyze which genes were more likely to appear in migraines sufferers versus healthy folks.

That was where they discovered an increase in the number of genes that encode nitrate, nitrite and nitric oxide-related enzymes in patients who struggle with migraines. Plus, those genes associated with migraines were far more prevalent in oral samples.

A probiotic solution?

Interestingly, this discovery may lead to more targeted migraine treatments like a mouthwash or probiotic to restore the proper balance, according to Dr. Embriette Hyde, a co-author of the study as told to CNN. Could it be possible that probiotics could become a go-to treatment instead of migraine medication? Maybe some day…

This suggestion makes good sense, based on previous research that found probiotic strains of beneficial bacteria from the Lactobacillus and Bifidobacterium families were powerful enough to reduce tooth decay and thrush.

Protecting your microbiome and overall health is as simple as taking a probiotic, ideally with multiple strains of bacteria, like EndoMune Advanced Probiotic and EndoMune Junior.

A diverse gut protects your health during immunotherapy treatments for cancer

For many cancer patients, undergoing chemotherapy or radiation are often a necessity, but they come with lots of risks depending on the severity and length of treatments.

Rather than bombarding tumors with chemo and radiation, however, some patients and their teams of doctors are choosing other cancer-fighting approaches like immunotherapy that work far differently.

Immunotherapy focuses on treating your body’s immune system to fight cancer either by supercharging a patient’s immune system or teaching his/her body how to spot cancer cells and eradicate them. Also, in some cases, immunotherapy can aid in a cancer patient’s recovery long after treatments have ended.

But not everyone responds well to immunotherapy, which has researchers scrambling for answers.

Over the years, cancer researchers have learned how good gut health plays a critical role in protecting cancer patients during chemo treatments.

A diverse gut microbiome may also be very important in how well the human body handles certain forms of immunotherapy, according to a study presented at a recent symposium sponsored by American Society of Clinical Oncology.

A team of researchers, led by senior study author Dr. Jennifer Wargo from the University of Texas MD Anderson Cancer Center, studied the connections between a healthy gut and the benefits of immunotherapy by examining fecal and oral bacteria samples taken from more than 200 patients fighting metastatic melanoma, an advanced form of skin cancer.

Ninety-three patients received an anti-PD1 immune drug that blocked a pathway protecting tumor cells from a patient’s immune system equipped to fight it.

From that smaller group, scientists studied fecal samples provided by 30 patients who responded to immunotherapy and 13 more who didn’t.

No surprise, patients who responded to the anti-PD1 drug had greater diversity of gut bacteria and for a specific type of bacteria (Ruminococcaceae). Plus, an examination of their tumors uncovered a greater number of cancer-fighting immune system cells (CD8+T).

On the other hand, patients whose bodies didn’t react to immunotherapy drugs had much lower gut diversity and one specific family of gut bacteria (Bacteriodales).

“Meanwhile, we need concerted research efforts to better understand how the microbiome may influence immune responses, as well as an in depth view on how we can tweak the microbiome so that more patients can benefit from immunotherapy,” said Dr. Wargo, an associate professor of genomic medicine and surgical oncology, according to a press release.

Some of that tweaking may come from changing a patient’s dietary habits or boosting the diversity of their gut by recommending a probiotic, scientists said.

Although taking a probiotic is beneficial for your health, many believe eating a cup of yogurt or taking a cheap supplement containing one or two strains of bacteria is good enough.

The real value of taking a multi-strain probiotic like EndoMune Advanced Probiotic: Ten strains of beneficial bacteria plus the prebiotic FOS provide 20 billion allies that protect your health every day.

Probiotics may treat spinal cord injuries

The results of recent studies of the human gut and how it touches so many different health conditions is just amazing. So much so, scientists have discovered all sorts of new uses for probiotics that few would’ve considered previously.

Innovations ranging from protecting your teeth from thrush to treating burns and other kinds of physical trauma all hinge on the incredible ability of probiotics to provide incredible benefits when the health of the gut is compromised.

One day, probiotics may become a key component in treating spinal cord injuries, based on the findings of research conducted on mice at Ohio State University and featured in the Journal of Experimental Medicine.

Researchers came to this conclusion after studying the health of mice whose guts suffered from dysbiosis (an imbalance between harmful and beneficial bacteria).

Overall, mice that recovered poorly from spinal injuries experienced the most changes in the makeup of their gut microbiomes. What’s more, mice that were pretreated with antibiotics prior to their injuries experienced higher levels of spinal inflammation and reduced functional recovery, according to the study.

To the good, mice that received daily doses of probiotics containing large amounts of lactic acid-producing bacteria experienced less spinal damage, regained more movement in their hind limbs and had healthier gut microbiomes too.

Scientists believe the probiotic mix they fed injured mice triggered regulatory T cells (gut-related immune cells) that may have slowed down inflammation and could have prevented extra damage to the spinal cord after their injuries.

Another possible explanation could be a kind of gut-brain axis link as the bacteria contained in the probiotic may be secreting beneficial chemicals that enhance the growth and functioning of neurons.

“Either or both of these mechanisms could explain how post-injury disruption of the gut microbiome contributes to the pathology of spinal cord injuries and how probiotics block or reverse these effects,” says Dr. Philip Popovich, principle investigator and director of The Center for Brain and Spinal Cord Repair at Ohio State’s Neurological Institute in a press release.

So, what’s next for researchers measuring the value of a healthy gut in treating all kinds of health problems? The sky’s the limit!

You can do your part to protect your health from all kinds of ailments naturally, even those yet to be discovered, by taking a probiotic featuring multiple strains of beneficial bacteria like EndoMune Advanced Probiotic.

 

 

 

Colon cancer patients are getting younger

For the longest time, the incidence of colon cancer — the second leading cause of cancer deaths among men and third among women in America — has been confined to older people.

Some 90 percent of all new cases of colon cancer occur in patients age 50 and older, and the average age of diagnosis has been age 72. Until now…

Research by the American Cancer Society has shown a steady uptick in colorectal cancer rates among young and middle-age adults including those in their early 50s, according to a recent report in the Journal of the National Cancer Institute.

By the numbers

Based on a deeper look at the demographics, researchers discovered colon cancer rates had increased by as much as 1-2 percent per year from the mid 1980s to 2013 among adults ages 20-39.

The numbers are even more alarming for rectal cancer, with cases rising about 3 percent annually among adults ages 20-29 (1974-2013) and adults ages 30-39 (1980-2013).

“Our finding that colorectal cancer risk for millennials has escalated back to the level of those born in the late 1800s is very sobering,” said Dr. Rebecca Siegel of the American Cancer Society, according to a press release.

In fact, the trend toward younger colon cancer patients over the past two decades has closed a once wider gap in disease risks and patients in their early 50s compared to those in their late 50s, the study says.

Also, an increase of new cases among patients ranging in age from their 40s to early 50s in 2013 has prompted researchers to suggest starting colorectal cancer screenings for patients at average risk earlier than age 50.

(Due to higher incidences and lower survival rates, the American College of Gastroenterology published guidelines that recommend colon cancer screenings for African-Americans starting at age 45.)

5 ways to prevent colon cancer

No matter how gloomy the stats appear on the surface, the underlying good news here is that it’s pretty easy to reduce your risks of colon cancer if you’re willing to take some simple preventative steps.

  1. Get screened! There are an array of tests at your disposal, from a high-sensitivity fecal occult blood test (FOBT) done annually to the flexible sigmoidoscopy (five years) and colonoscopy (10 years).
  1. Fight the obesity bug with exercise and a healthy diet. Obesity increases your odds of colon and rectal cancer by 30 percent, and higher BMIs elevate those cancer risks among men even more. Instead of trying and failing to conquer obesity with a home run punch, however, many scientists suggest a more measured, steadier approach. In fact, a 2016 study from Washington University concluded the greatest health benefits come from patients losing just 5 percent of their body weight.
  1. Take a supplement. If you’re taking a daily supplement for your good health, make sure it includes the right amount of vitamin D (1,000 IU) and calcium (1,000-1,200 mg), two proven colon cancer fighters.
  1. Reduce your contact with antibiotics and antibacterial soaps. Relying too often on antibiotics not only upsets the healthy balance of bacteria in your gut. Exposure to a common antibiotic like penicillin can increase your risk for colon cancer by promoting a “pro-inflammatory environment” for up to a decade before a diagnosis. Plus, it’s time to give up antibacterial soaps, toothpastes and personal hygiene products that contain triclosan, an endocrine disruptor and antimicrobial compound linked to bacterial resistance.
  1. Take a probiotic. The best step to ensure your continued good health, and protect the healthy balance of bacteria in your gut: Take a multi-strain probiotic like EndoMune Advanced Probiotic or EndoMune Advanced Junior (for your kids).
fruits and nuts

Mind your gut for a beautiful mind

There is a strong connection between the brain and the gut. Researchers claim there lies a brain in the gut with its own neural network.

The Enteric Nervous System ( ENS ) has a robust system that manages the hormones, emotions, and neurotransmitters, which communicate with the brain. Serotonin, dopamine and gamma-Aminobutyric acid (GABA) are all neurotransmitters that play a role in the intestines and the central nervous system. They can be transmitted to the brain through the blood or the vagus nerve.

There are trillions of gut microbiota residing in the gut that can directly impact our mental state. Sometimes when we are anxious or depressed it can in part be due to an unhealthy balance of the intestinal bacteria (dysbiosis).  Among women who suffer from depression, anxiety and GI difficulties, study results suggest a link to the gut rather than the brain.

5 Ways to Manage a Better Gut for a Better Mind

Managing the gut can result in benefits for the mind, including a better harmony between the gut and mind. Here are five ways that can create that powerful force within your body.

1. Diet

Diet is the core of every change in the body. The proverbial you are what you eat stands true in this case. The fuel you use to energize your body provides the essential nutrients and has a strong effect on every activity in the body.

Certain diets elicit a healthier bacterial balance. A diet rich in whole, unprocessed, unadulterated, and non-genetically modified foods helps to maintain a proper balance of the gut bacteria. Eliminating foods that are processed and choosing fresh and real foods is the key to providing the gut with healthy bacteria.

2. Lower Your Sugar Intake

Sugar brings about a lull in the body. It slows down the body. Sugar and carbohydrates affect the system by nurturing the pathogenic bacteria.

In a recent study, researchers fed a group of mice a diet high in sugar and then tested their mental and physical function. The sugar diet negatively impacted the mice’s gut microbiota, impaired their cognitive flexibility, and ability to efficiently adapt to changing situations. The change in gut bacteria also adversely affected the mice’s long-term and short-term memory.

Sugar affects adaptability. The sugar spike in blood levels makes the body work harder. It also leads to gut inflammation. Consuming less sugar can be beneficial for the gut and the brain.

3. Add a Probiotic

Healthy foods such as lacto fermented kimchi, pickles, sauerkraut, and other traditional vegetables have microbes that have a positive effect on our gut. A common ancestral practice to consume fermented foods rich in probiotics is quite interesting. Healthy fermented foods are filled with probiotics that allow all the healthy fauna to settle in the gut and flourish.

In a 2013 study in Gastroenterology, 12 out of the 25 healthy women ate a cup of yogurt twice a day for four weeks. The rest of the women ingested no yogurt. All women had pre and post brain scans while being asked to respond to a series of images depicting different facial expressions. Results indicated that the women who ate yogurt were calmer when shown various emotions than the control group. The results revealed that the yogurt changed the subjects’ gut microbiota, which also modified their brain chemistry.

Consuming good probiotics are one great way to keep the gut healthy. Alive organisms when ingested in adequate amounts, produces a health benefit in patients suffering from psychiatric illness.”  A review by Dinan et al encompasses the clinical basis for the use of probiotics in mental health with reference to animal studies in which behavioral changes resulted from exposure to bacterial strains such as  Bifidobacterium and Lactobacillus. In placebo-controlled trials in humans, measures of anxiety, chronic fatigue, depression and anxiety are associated with irritable bowel syndrome (IBS). IBS is felt to be due to an imbalance or dysbiosis of the gut microbiota.

Besides foods, a good probiotic supplement with a number of strains can be very helpful for the gut.

4. Exercise Regularly

Exercise releases the good hormones in our bodies. These hormones help to stimulate growth and make us feel happy. All the chemicals and hormones released during exercise benefit the body, and eventually the gut. Regular exercise stimulates better bowel movements and leads to more water consumption. All these affect the gut, keeping it healthy and strong.

Exercise can be the best therapy for a weak gut. So whenever you feel low, experience anxiety or have a stressful meeting coming up, go for a run, hit the gym and take a probiotic like EndoMune Advanced.

5.  Relax and De-stress

A stressful mind releases harmful hormones like cortisol. A rise in cortisol affects the gut making the cholesterol level higher, and even triggers depression.

A relaxed mind can induce hormones that promote relaxation, which also affect the gut. Studies have shown stress puts us at risk for dysbiosis, a shift away from healthy gut diversity.

In a 2015 study from Harvard University affiliates, forty-eight patients with either IBS or Inflammatory Bowel Disease (IBD) took a 9-week session that included meditation training. The results showed reduced pain, improved symptoms, stress reduction, and a decrease in inflammatory processes.

Practicing mindful techniques of relaxing the mind, and breathing more deeply to oxygenate the body lead to a less distressed mind and gut. The best way to develop a beautiful mind is to cultivate a healthy and happy gut.

To learn more about your gut/brain connection, talk to your health care provider and ask if adding a probiotic like EndoMune Advanced Capsules to your daily regimen will help issues likes anxiety and depression.

Probiotics may lower the risk for heart disease? Research says, ‘yes’!

Every year nearly 735,000 Americans have a heart attack. Of these, 525,000 are a first heart attack and 210,000 happen in people who have already had a heart attack. While these numbers are staggering, the first step towards fighting cardiovascular problems and lowering cholesterol levels starts with a living a healthy lifestyle that includes a balanced diet, daily exercise along with adding a probiotic supplement.

Further research and studies conducted on probiotics show that gut health can be related to the heart. A healthy gut with a rich flora of life-supporting bacteria can mean the prevention of many health issues, even preventing and treating heart ailments.

Research shows probiotics can lower the risk for cardiovascular disease by limiting two risk factors:

A new Cleveland Clinic study links a particular type of metabolite called Trimethylamine (TMA) N-oxide or TMAO as a recently discovered independent risk factor for coronary artery disease and strokes. This chemical interacts with the lining of our arteries leading cholesterol plaques. Harmful intestinal bacteria breakdown a chemical called choline that is in egg yolk, liver, beef, and pork. The breakdown metabolite called TMA is converted by the liver into TMAO.

TMAO: The New Culprit

High plasma levels of TMAO correlated with an increased risk of major adverse cardiovascular events that is independent of traditional risk factors like hypercholesterolemia (high cholesterol), smoking and hypertension. The authors of the study recommend limiting the intake of the choline containing foods and adding a beneficial probiotic that will reduce the harmful bacteria that metabolize choline. “This is a very exciting study,” said Dr. Crandall. “It gives us a brand new way of looking at heart disease. It also opens an avenue for new tests and treatments.”

The discovery of the heart disease-causing bacteria might explain why about half of those who die of sudden heart attacks have no known risk factors for heart disease, like high blood pressure, cholesterol or diabetes, he noted.

Lowering circulating blood total cholesterol and LDL cholesterol (bad cholesterol)

In another study from the American Heart Association, researchers tracked cholesterol esters bound to saturated fat, which has been linked to dangerous arterial plaque buildup and occurs at higher levels in coronary artery disease in patients.

The study involved 127 adult patients with high cholesterol. About half the participants took a probiotic called Lactobacillus reuteri NCIMB 30242 twice a day while the other half of the group were given placebo capsules. Those taking the probiotic had LDL levels 11.6 percent lower than those on placebo after nine weeks. Furthermore, cholesterol esters were reduced by 6.3 percent and cholesterol ester saturated fatty acids by 8.8 percent, compared with the placebo group.

Scientists have proposed that Lactobacillus bacteria alone may impact cholesterol levels in several ways, including breaking apart molecules known as bile salts which results in lower production of cholesterol by the liver.

If you are struggling with cholesterol-related health problems or are on a weight loss program that isn’t working for you, consider meeting with your medical practitioner and adding a high quality probiotic like EndoMune to lessen risk factors for cardiovascular disease.

Counteract the Holiday Cold with Probiotics

With the weather changing and people packing indoors, more and more people are contracting cold and cold-like symptoms. Now, during the hustle and bustle of the holiday season, is the time to offset the spread of cold and upper-respiratory viruses.

A small study conducted by researchers from the University of Medicine and Dentistry of New Jersey and published in the British Journal of Nutrition examined the connection between probiotics and reduced cold and upper-respiratory infection symptoms. In this double-blind study, nearly 200 students were divided into two groups, one receiving a daily probiotic supplement and the other receiving a placebo.

The results concluded that the study participants that took the probiotic supplement had a reduced length of cold by two days, missed less class days and had 34% less severe symptoms.

Adding a daily probiotic supplement, like EndoMune Advance, may help kick those coughs and sniffles away, just in time to enjoy the close company of family and friends.

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