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Safe to use Probiotics to help treat type 2 diabetes.

Probiotics: An Effective Treatment For Type 2 Diabetes?

Digestive Health, Disease, Drug interactions, Probiotics / By @drHoberman

Summary: Is it safe and helpful to take a probiotic if you’re coping with type 2 diabetes? This survey of studies gives a thumbs-up to probiotics!

As the epidemic of metabolic syndrome continues in America — thanks to a Western lifestyle that can kill you faster than smoking — the number of Americans dealing with type 2 diabetes is growing by the day.

Among the 38 million Americans who currently suffer from diabetes, roughly 90 percent of them are dealing with type 2 diabetes. (An alarming 22 percent don’t even know they have diabetes at all!)

You can do plenty of things to manage your health if you have type 2 diabetes, from diversifying your diet to include more unprocessed whole foods to finding more time during day to get moving with some form of exercise.

Researchers have also learned so much about how an unbalanced gut microbiome affects many aspects of human health, including how it creates many challenges for type 2 diabetes patients trying to regulate their blood sugar.

If you or a loved one is struggling with managing type 2 diabetes, taking a probiotic should be at the top of your to-do list too, based on a recent review of 33 studies appearing in Nutrients.

Nearly two-thirds of the studies Canadian researchers reviewed reported improvements in at least one measurement related to glycemic levels while taking a probiotic.

In addition, nearly half of those reports cited improvements in lipid levels after taking a probiotic. That’s very important given that elevated levels of LDL lipoproteins can greatly raise one’s risks of cardiovascular diseases.

Also, the benefits of multi-strain probiotics formulated with strains from the Lactobacillus and Bifidobacterium families really stuck out with 16 studies reporting improvements in at least one glycemic measurement.

This makes sense given that the Bifidobacterium family enhances the production of healthy fatty acids and the digestion of fiber while promoting immune health and the Lactobacillus family assists the protection of the barrier lining the gut.

Finally, probiotics also worked very well with metformin, a go-to drug prescribed for type 2 diabetics, enriching the composition of gut bacteria, decreasing insulin resistance and increasing the abundance of beneficial short chain fatty acids (SCFAs).

While there’s much more research to be done, there’s little doubt that probiotics, especially those formulated with multiple strains of bacteria like EndoMune Advanced Probiotic, can be a boon to the health of type 2 diabetes patients.

Resources

Nutrients

News-Medical.net/Life Sciences

CDC

Mayo Clinic

Medline Plus

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woman holding white pill tablets in hand with glass of water

How Drugs Interact With Your Gut

Drug interactions / By @drHoberman

The gut microbiome is a vital and important part of human health that touches so many aspects of our daily lives, yet it works in very unpredictable ways.

For example, consider how certain drugs interact with the human gut. Sometimes, they do work but not so well at other times, as we learned about statin drugs.

The very same thing may be true about metformin, the go-to drug prescribed for type 2 diabetic patients to control high blood sugar, according to a study appearing in EBiomedicine.

“For example, certain drugs work fine when given intravenously and go directly to the [blood] circulation, but when they are taken orally and pass through the gut, they don’t work,” says senior study author Dr. Hariom Yadav, a researcher at the Wake Forest School of Medicine.

As we’ve seen previously, metformin works well with the gut, although some patients who take it tend to experience more side effects (nausea, diarrhea and flatulence).

Based on their review of studies, Wake Forest researchers determined the metabolic capacity of a patient’s microbiome may influence how various drugs aimed at treating type 2 diabetes are absorbed and function in effective, inactive or even toxic ways.

“We believe that differences in an individual’s microbiome help explain why drugs will show a 90 or 50 percent optimum efficacy, but never 100 percent,” Dr. Yadav said.

Now, Wake Forest researchers are taking the next important gut-friendly step by testing prebiotics, a natural component of non-digestible plant fiber that feeds the good bacteria living in your gut, and probiotics that may help diabetes drugs work more effectively.

Could a multi-species probiotic containing 10 kinds of beneficial bacteria plus a handy prebiotic (FOS) like EndoMune Advanced Probiotic make gut-friendly difference in the way patients take their drugs?

The evidence is growing!

How Drugs Interact With Your Gut Read More »

a man holding whole foods standing near a window

Fight Type 2 Diabetes with a Healthy Gut

Digestive Health, Disease, Healthy Aging / By @drHoberman

There’s no disputing the health benefits of eating whole foods — legumes, vegetables, fresh fruits and whole grains – rich in dietary fiber.

For a long time, science has recognized the role good gut health plays with help from dietary fiber in treating diseases like type 2 diabetes without really understanding how both converge to promote better overall health.

The results of a Chinese study that treated type 2 diabetes patients partly with a high-fiber diet may offer a critical clue, based on a tiny group of bacteria in the human gut.

A select group of gut bacteria

Researchers split patients into two groups: A control group who received standard dietary recommendations and patient education and a more active group who was prescribed a high-fiber diet containing many kinds of dietary fiber from whole grains, prebiotics and Chinese medicinal foods, according to the study featured in Science.

After 12 weeks, patients following the fiber-rich diet created by scientists that jump-started the development of short-chain fatty acids (SCFAs) had done its job.

Those patients in the active group experienced sharply reduced blood glucose levels at faster rates and lost extra weight too.

How did high-fiber diets make such a difference?

Researchers believe diseases like type 2 diabetes may occur as a result of problems in producing SCFAs in the gut. Surprisingly, a tiny number of gut bacteria – 15 out of a possible 141 strains – were affected by eating a high-fiber diet. In fact, this select group became the dominant strains in the guts of patients, after increasing butyrate and acetate levels.

Simply, the presence of higher levels of butyrate and acetate (both are SCFAs) created mildly acidic environments that decreased the amounts of bad bacteria in the gut, leading to a greater production of insulin and improved blood glucose control.

“Our study lays the foundation and open the possibility that fibers targeting this group of gut bacteria could eventually become part of your diet and your treatment,” says Dr. Liping Zhao, lead author of the study and a professor in the Department of Biochemistry and Microbiology at Rutgers University, according to a press release.

More whole-grain goodness

This select group of gut bacteria may also be at work in the results of a study appearing in Gut, in which 60 Danish adults followed a high whole-grain diet (more than 100 grams per day) and a low refined grain diet (13 grams per day) alternately for eight-week periods.

Compared to the refined grain diet, patients eating a diet rich in whole grains lost weight and lowered the number of markers associated with inflammation that causes metabolic syndrome.

That’s a cluster of conditions ranging from elevated blood sugar levels to extra body fat around the waist that increases your risk of serious cardiovascular problems and diabetes.

Are you having trouble losing weight? Are you fighting a losing battle against metabolic syndrome?

To prevent metabolic syndrome from harming your health further and begin the healing process, restore the proper balance of gut bacteria with the help of EndoMune Metabolic Rescue and its unique probiotic blend of Bifidobacterium lactis and the prebiotic XOS.

How EndoMune Metabolic Rescue works

Unfortunately, the number of Bifidobacteria in your gut decline as your body ages, largely due to a changing diet that usually contains more fiber-free foods.

That’s where your adult gut needs extra help from a prebiotic, a substance made from non-digestible starches that literally feed your gut by promoting the growth of beneficial bacteria.

In recent years, XOS has emerged as a versatile, natural prebiotic that can provide many benefits, for example, reversing imbalances in the human gut during the development of type 2 diabetes to healthier ones.

EndoMune Metabolic Rescue’s unique formulation of Bifidobacterium lactis (a beneficial subspecies of Bifidobacteria) works as a synbiotic to produce SCFAs, stimulating the production of hormones that could slow down activity in the appetite center of your brain.

This hormonal action also slows down the motility (emptying) of your stomach, which promotes the sense of fullness or satiety. In other words, it takes less food to feel full.

Research related to consuming XOS has found increased amounts of Bifidobacteria in test subjects. Other studies have shown how patients given Bifidobacteria lactis can metabolize resistant starches like XOS, producing the SCFAs that act as signals to reduce appetite and slow down stomach motility, ideally resulting in weight loss and a healthier gut.

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