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Children’s Health

Children’s Health Issues

infant allergies

Reverse infant milk allergies with probiotics

An estimated 2.5 percent of children under age 3 are allergic to cow’s milk. Overall, milk allergies are the most common food allergy for infants and small children, according to Food Allergy Research & Education (FARE).

Cow’s milk allergy symptoms can vary from mild to life-threatening, and should not be confused with lactose intolerance, a condition, while problematic, isn’t fatal.

Most young children eventually outgrow these allergies, according to FARE. Until then, medical experts recommend babies be fed hydrolyzed, casein-based formulas containing altered proteins that are easier and safer for their growing young systems. Moms must keep a vigilant eye on product labels to avoid milk-based ingredients too.

Concerns about milk allergies led scientists from the University of Chicago to find a safer treatment in probiotics, according to a study featured in The ISME Journal.

Researchers tested a probiotic formula containing the proprietary strain Lactobacillus rhamnosus GG (LGG) by analyzing and comparing stool samples taken from healthy infants who consumed the probiotic formula and babies given the formula without the probiotic.

Babies with cow’s milk allergies had significantly different compositions of gut bacteria compared to healthy children, which may have had an influence on their development.

Overall, babies whose bodies responded to the probiotic formula had higher amounts of gut bacteria when compared to children who didn’t, developed a similar tolerance.

This tolerance is connected to specific bacterial strains that produce butyrate, a byproduct of the metabolization of fiber providing nourishment for colon lining cells and linked to cancer-fighting benefits.

“The ability to identify bacterial strains that could be used as novel therapeutics for treating food allergies is a fundamental advance,” said Dr. Jack Gilbert, Associate Professor in the Department of Ecology & Evolution at the University of Chicago and co-author of the study, according to a press release.

Another probiotic formulation containing a proprietary strain of Lactobacillus rhamnosus was also responsible for providing a safe, long-term solution for treating peanut allergies earlier this year.

With all of this attention on probiotics, it may be just a matter of time before scientists test a non-proprietary strain of Lactobacillus rhamnosus like the kind contained in EndoMune Advanced Probiotic and EndoMune Junior to treat food allergies.

Despite the good news about probiotics treating infant food allergies, always consult with your doctor or pediatrician first so they can provide the proper course of action for your child’s specific health condition.

Reverse infant milk allergies with probiotics Read More »

Moms: Stressing out may affect your new baby’s brain, gut health

A number of variables affect the health of newborn babies, from preeclampsia to caesarean (C-section) births, which have a direct connection to a mother’s gut health.

The vaginal microbiota of an expectant mom experiencing stress may be affected during her first trimester. Some emotions could trigger changes in the way her baby’s gut health and brain develop, according to a recent study appearing in the medical journal Endocrinology.

“As the [newborn’s] gut is initially populated by the maternal vaginal microbiota, changes produced by maternal stress can alter this initial microbial population as well as determine many aspects of the host’s immune system that are also established during this early period,” says Dr. Tracy Bale, senior author of the study and a professor of neuroscience at the University of Pennsylvania’s Perelman School of Medicine and its School of Veterinary Medicine, via a press release.

Researchers tested their theory by exposing pregnant mice to various stressors, including unique noises, odors of established predators and restraints, during the animal’s equivalent of their first trimester.

Shortly after giving birth, scientists examined the vaginal microbiota of the mothers along with the gut microbiota from their offspring. Additionally, they examined how amino acids travel in the brains of pups to measure development and metabolism.

Exposure to stressors had lasting effects on the vaginal microbiota of pregnant mice that were observed, not only in the gut microbiota, but in the metabolism and neurodevelopment of their babies too.

Neurodevelopment issues were most pronounced among males, a finding Dr. Bale and her colleagues discovered in a prior study. These alterations could be a sign of serious neurological disorders to come like schizophrenia and autism, conditions that affect males far more often.

Scientists also conducted a supplemental experiment that showed how important it is for moms to deliver their babies vaginally. Baby mice born via C-section had their gut microbiomes restored to those of vaginally-delivered offspring only after receiving transplants from the vaginal microbiomes of female mice.

Despite the challenges new moms face by delivering their babies via C-section, there’s growing evidence that giving newborns a probiotic could enhance their developing gut health and lessen problems with colic.

When shopping for the right probiotic for your young child, consider EndoMune Junior, which contains important building blocks such as Lactobacillus and Bifidobacterium.

Moms: Stressing out may affect your new baby’s brain, gut health Read More »

Poor gut health may be responsible for the terrible toddler twos

Your toddler’s unique gut microbiome may contribute to those mood swings associated with the “terrible twos.”

There may be more going on besides fussy behavior, according to researchers at Ohio State University’s Center for Clinical and Translational Science.

Those mood swings may provide indicators for early stages of chronic diseases, like allergies, asthma, bowel disease and even obesity, according to a recent study appearing in the journal Brain, Behavior, and Immunity.

Evidence has shown that intestinal bacteria interact with stress hormones, the very same ones linked to chronic illnesses like obesity and asthma, says Dr. Lisa Christian, a researcher with Ohio State’s Institute for Behavioral Medicine Research.

“A toddler’s temperament gives us a good idea of how they react to stress. This information combined with an analysis of their gut microbiome could ultimately help us identify opportunities to prevent chronic health issues earlier,” Dr. Christian explained.

Based on an analysis of 77 stool samples taken from young boys and girls ages 18-27 months old, there were signs of activity in the gut-brain axis, says Dr. Michael Bailey, study co-author, microbiologist and member of the Institute for Behavioral Medicine Research.

“There is definitely communication between the bacteria in the gut and the brain, but we don’t know which one starts the conversation.”

No matter which side “started the conversation,” evidence appears to link young temperaments to the amount and diversity of gut bacteria, even after taking into account their diets, the mother’s birthing method and whether or not they were breast fed.

Matching gut bacteria to behaviors

Mothers were asked to assess their child’s behaviors using questionnaires that gauged 18 specific traits that fed into specific scales of emotional reactivity.

Based on those reports, researchers analyzed the different genetic types and quantities of gut bacteria in those stool samples (along with diets).

With improvements in DNA testing, which enable scientists to spot individual bacteria and concentrations in stool samples, “All of the predominant bacteria we found in our study have been previously linked to either changes in behavior or immune responses,” says Dr. Bailey, according to a press release.

Girls vs. boys

Generally, children who had the most genetically diverse gut bacteria more often displayed the behaviors connected with positive mood, impulsivity, sociability and curiosity.

Scientists have also been able to link extroverted personality traits in boys to an abundance of gut microbes from specific families (Ruminococcaceae and Rikenellaceae) and genera (Parabacteroides and Dialister).

“It’s possible that more outgoing kids could experience less trouble due to fewer stress hormones in their guts than those who are shy. Healthy guts regulate the production of stress hormones better or it could be a bit of both,” Dr. Bailey says.

The links between gut bacteria and temperament were less consistent in girls according to the study. Still, scientists linked some traits in girls — focused attention, self-restraint and cuddliness — to a less diverse microbiome.

Also, girls who had more of one particular family of gut bacteria (Rikenellaceae) experienced more fear than others with better balance in their gut health.

What makes a real difference?

Although researchers concluded diets didn’t make a difference in the behaviors and gut health of the toddlers they examined, they left room for the possibility that they could.

“It is certainly possible that the types or quantities of food that children with different temperaments choose to eat affect their microbiome,” says Dr. Christian.

Despite the findings in this study, evidence points to the method of birth — vaginal delivery versus caesarean — being a huge factor. Babies born via C-section had less gut diversity than those who were born naturally.

What’s more, the growing immune systems of small children aren’t nearly as prepared for challenges to come if they don’t have the right balance of gut bacteria. That’s where probiotics can help your child, whether he or she is a newborn, toddler or school age child.

That’s why EndoMune Junior now comes into two varieties: a powdered formula, ideal for mixing into food or drinks and a delicious chewable berry-flavored tablet that will leave them wanting more.

Each dose of EndoMune Junior contains 10 billion CFUs, including four species of proven health-promoting bacteria, and a prebiotic that feeds the good bacteria already in your child’s gut.

Poor gut health may be responsible for the terrible toddler twos Read More »

The gut health mix of young babies may signal food allergies, asthma

The lack of diversity in the gut is a clear sign there are health problems looming, as we’ve seen in recent reports linked to obesity and heartburn drugs. Unfortunately, that reprogramming of human gut diversity may start much earlier, during the very early stages of childhood development before birth due to early exposure to antibiotics.

New research from Canadian scientists at the University of Alberta and University of Manitoba published in Clinical & Experimental Allergy has discovered that the lack of gut diversity among babies as young as three months old, may be a warning sign about the early development of asthma or food allergies.

Gut diversity matters

Researchers examined data collected from 166 infants enrolled in the Canadian Healthy Infant Longitudinal Development (CHILD) study. This ambitious study is closely monitoring the health of more than 3,500 families and their newborn infants to provide more knowledge about the genetic and home environmental factors that trigger asthma and allergies.

Scientists used DNA techniques to classify the good bacteria in stool samples taken at three months and age one, then identified which bacteria were present when food allergies began to emerge later in life (based on a skin reaction test to foods).

Overall, only a dozen babies experienced sensitivities to foods. No surprise, infants with less diversity of specific types of gut bacteria—Enterobacteriaceae (too much) and Ruminococcaceae and Bacteroidaceae (not enough)—at three months were more likely to develop allergies to peanuts, eggs and other foods by the time they reached age one.

“It is something that one can measure which indicates increased risk of food sensitization by one year of age,” said Dr. Anita Kozyrskyj, professor in the Department of Pediatrics at the University of Alberta and senior author of the study in a press release.

Scientists hope to expand the sample size as data comes from other Canadian cities to some 2,500 children across the country, tracking them as they grow up, then re-examining the findings again at ages three and five.

Protect your baby’s gut health

The good news: Protecting and improving the diversity of your baby’s gut health can be as safe and convenient as giving him/her a probiotic like EndoMune Advanced Junior, made from four different strains of beneficial bacteria plus the prebiotic fructooligosaccharide.

Each dose of Endomune Advanced Junior features 10 billion CFUs of good bacteria and contains no artificial colorings, dairy products, preservatives or sugar and is certified Kosher and gluten-free.

The gut health mix of young babies may signal food allergies, asthma Read More »

A healthy gut protects your newborn’s brain

When discussing the gut and the brain, typically the conversation turns to the gut-brain axis, the connection that ties your brain and emotions to your intestines.

A recent study on mice conducted by researchers in Sweden, Singapore and the U.S. has discovered another connection between the gut and brain, but this one guards the brain from damaging chemicals in the blood, even before birth.

This relationship is related to the blood-brain barrier, a semi-permeable “network” of blood vessels that separates the brain from the body’s circulatory system and protects the central nervous system from toxins, blood-borne infections and other harmful substances while maintaining stability and regulating the movement of essential molecules.

Scientists found this link by comparing the development of the blood-brain barriers of two sets of mice. One group of germ-free mice was raised in a sterile environment away from bacterial contact, while the other group was exposed to typical bacteria in a “normal” environment.

Normal vs. Sterile Environments

The results of this study aren’t surprising if you recall our recent posts about the quest for too much cleanliness via the hygiene hypothesis, causing so many health problems.

The differences between both sets of mice started before birth. The gut health of mothers raised in a normal environment protected the brains of mice before they were born by blocking labeled antibodies from circulating into brain tissues. Conversely, those same-labeled chemicals “leaked” into the brains of pups from germ-free mothers.

Also, the leakiness of the blood-brain barrier among germ-free mice continued as they aged from babies to adulthood. While the exact process is still being identified, researchers determined tight junction proteins (important to the permeability of the blood-brain barrier) changed structurally and acted differently in the absence of bacteria.

“These findings further underscore the importance of the maternal microbes during early life and that our bacteria are an integrated component of our body physiology,” says Prof. Sven Pettersson, the principal investigator at the Department of Microbiology, Tumor and Cell Biology at the Karolinska Institute in a press release.

“Given that the microbiome composition and diversity change over time, it is tempting to speculate that the blood-brain barrier integrity also may fluctuate depending on the microbiome. This knowledge may be used to develop new ways for opening the blood-brain barrier to increase the efficacy of the brain cancer drugs and for the design of treatment regimes that strengthens the integrity of the blood-brain barrier.”

Protecting C-Section Babies

In the human world, babies delivered via a caesarean (C-section) have serious health problems like those young germ-free mice from the beginning of their young lives due to a lack of diversity in their gut microbiomes.

This gut health challenge puts babies at a higher risk for many health problems down the road, ranging from allergies and obesity to diabetes and irritable bowel syndrome (IBS).

A safe, simple, non-drug solution that protects and enhances the diversity of your baby’s gut health and lessens prolonged crying and discomfort due to colic and other digestive problems: Give them a multi-species probiotic, like EndoMune Advanced Junior (for kids).

A healthy gut protects your newborn’s brain Read More »

Moms: Are you limiting your baby’s exposure to antibiotics?

When taken too often, antibiotics are harmful to gut health. Medical evidence proving such damaging effects has grown significantly over the past year.

The main hazards linked to taking too many rounds of antibiotics have centered on a growing vulnerability to Clostridium difficile (C. diff) infections and obesity in adults.

Unfortunately, the harm antibiotics do to human health may start much earlier, during the early stages of childhood development—even before your baby is born—and may last for a lifetime, according to a pair of recent studies.

Reprogramming your baby’s gut health with antibiotics

Researchers at NYU’s Langone Medical Center studied the effect low doses of penicillin given over a lifetime would have on the health of mice in a study published in the medical journal Cell.

The big picture conclusion: Starting in the last week of pregnancy or during nursing, mice given low doses of penicillin were more vulnerable to metabolic abnormalities including obesity than animals exposed to antibiotics later in their lives.

In the main experiment, researchers compared the effect of penicillin on three groups of rodents: Two groups received penicillin—one before birth and the other later after weaning—then for the remainder of their short lives, while a third control group was given no antibiotics at all.

Both groups of mice that were fed penicillin had higher amounts of fat on their little bodies than the control group, but the womb group was the fattest, providing solid proof that mice were “more metabolically vulnerable if they get antibiotics earlier in life,” says Dr. Laura Cox, lead author of the study.

Not only did penicillin-treated mice carry twice as much fat compared those fed only high-fat food, but their bodies also showed signs of metabolic disorders.

Do antibiotics lessen the amount of gut bacteria? Not necessarily…

Scientists took another important step by transferring gut bacteria from penicillin-treated mice and those not given the antibiotic to antibiotic- and germ-free mice shortly after the time they would be weaned (three weeks old).

Mice given gut bacteria from donors treated with antibiotics were fatter than those treated with antibiotic-free gut bacteria.

Another interesting discovery made by NYC researchers during their study may have overturned a long-standing belief that antibiotics (at least penicillin) reduces the amount of gut bacteria contained in the body.

As a whole, gut bacteria didn’t decrease, but four very important strains did: Allobaculum, Candidatus, Arthromitus, member of the Rikenellaceae family and the very popular Lactobacillus (one of the key bacteria ingredients in EndoMune Advanced Probiotic).

These results reaffirm the work conducted by one of the most popular researchers in the field of gut health research, Dr. Martin Blaser, director of the NYU Human Microbiome Program and author of the book, Missing Microbes: How the Overuse of Antibiotics is Fueling Our Modern Plagues.

More evidence broad-spectrum antibiotics may trigger obesity

A more recent study appearing in JAMA Pediatrics gets to the heart of the problem: Health problems occur when exposing babies under age 2 and up to age 5 to broad-spectrum antibiotics.

Using electronic records spanning 2001-13 from a network of primary health clinics, scientists tracked the health of more than 64,000 children from birth to age 5. The numbers speak volumes:

  • Nearly 70 percent of all children were exposed to antibiotics more than twice on average before they reached age 2.
  • Young children who were exposed to all antibiotics or broad-spectrum antibiotics four or more times had a greater risk of obesity.
  • The prevalence of obesity or being overweight increased over time from 23 percent at age 2 to 33 percent at age 4.

One additional factoid from the study that’s worth noting: No link was found between obesity and prescribing children narrow-spectrum antibiotics, medicines that treat a more select group of bacterial types, according to the Alliance for the Prudent Use of Antibiotics (APUA).

However, broad-spectrum antibiotics can handle a greater number of bacterial types and are often prescribed to treat a wider variety of infectious diseases or when the source of the infection is unknown, according to APUA. Varieties of broad-spectrum antibiotics include some synthetic penicillins, quinolones and aminoglycosides.

Because infants are so very vulnerable to antibiotics, especially soon after they’re born, it’s important for moms to work with their family pediatricians to ensure their babies get the healthy start they need to avoid metabolic problems that could lead to lifelong ailments like obesity.

The good news: A multi-species probiotic like EndoMune Advanced Junior can give your baby’s health a much-needed boost by protecting the diversity of beneficial bacteria in their gut and strengthening their tiny but growing immune systems.

Moms: Are you limiting your baby’s exposure to antibiotics? Read More »

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How probiotics are helping babies born via C-Section

So, you’re a mom with a newborn baby and you are doing all you can to keep the little one healthy and happy.

You’re swamped with so many important things like sleep, feeding times and reading up on everything to avoid allergies, jaundice and infection. It can add up to information overload, so any new knowledge — like the way mothers pass beneficial bacteria to babies during birth — can be overwhelming.

This last of a two-part series will help moms get up to speed on the value of protecting their babies’ gut health by giving them probiotics every day, particularly if you have had a caesarean (C-section) or other health issues during your pregnancies.

Protecting your baby’s immune health after a C-section

For moms, making the decision to deliver your newborn baby via C-section is a tough one. Often, that choice is already made for you due to biological obstacles that make a vaginal birth dangerous.

How probiotics are helping babies born via C-SectionFor some women, however, it doesn’t lessen the stigma of a C-section birth, even when it’s necessary. There’s no need to feel any way but good when you make the best delivery choices for your health and your baby’s health.

Unfortunately, C-section babies face a very real problem right after they’re born, based on a recent Swedish study that compared the health of 24 babies delivered vaginally and by C-section.

Scientists analyzed fecal samples from all two dozen babies taken a week after birth then five additional times, and took blood samples at 6, 12 and 24 months to check levels of immune system chemicals (Th1 and Th2) that may play a role in future allergy problems.

C-section babies had less gut diversity — a lower range of good gut bacteria — during the first two years of their lives (specifically the Bacteroides phylum that allows the immune system to respond to the right triggers) compared to babies born vaginally. Also, C-section babies had unbalanced levels of Th1 in their blood, making them more vulnerable to developing allergies.

(A 2010 study published in the Proceedings of the National Academy of Sciences found infants who were born via C-section had a gut microbiome resembling the mother’s skin, less rich in bacteria.)

Swedish researchers discussed further investigations into treatments that would normalize the development of the microbiota of C-section babies, including fecal transplants and giving them a daily probiotic.

Preventing eczema with probiotics

The benefits of giving your babies probiotics don’t stop with providing them good gut health and naturally boosting their developing immune systems.

Atopic dermatitis, better known as eczema, is an uncomfortable skin rash many babies have that first appears on the cheeks and scalp, and may later spread to their chest, arms, legs and other parts of their little bodies.

Although science hasn’t found what triggers eczema, environmental irritants and allergens may initiate this scaly problem. Also, if you or your family members have suffered from allergies, asthma or eczema, your baby has a better chance of suffering from it, too.

A 2013 study published in Clinical & Experimental Allergy found giving moms probiotic supplements of a strain of Lactobacillus rhamnosus (one of the 10 strains contained in EndoMune Advanced Probiotic) during pregnancies, then afterward to the babies for two years reduced the incidence of eczema sharply.

New Zealand researchers compared the effects of different bacterial strains on Moms and their new babies until they reached age 6 to determine which one had the best probiotic punch.

Lactobacillus rhamnosus supplements given to moms then their babies up to age 2 reduced the incidence of eczema in children by an amazing 44 percent until age 6.

Conventional medicine remains skeptical

Researchers found that giving probiotic drops to infants produced worse results than giving them a placebo. However, those results fly in the face of others, including a March study in JAMA Pediatrics, that quantified the benefits of giving babies probiotics as a savings of $119.

The appeal for new moms giving their babies probiotics certainly outstrips any conflicting issues. The amount of pages found on Google with the search term probiotics for baby is far bigger (6.9 million) than probiotics by itself (4.6 million).

How probiotics are helping babies born via C-Section Read More »

Why more expecting mothers are taking probiotics

There are many things a woman can do to promote a healthy pregnancy including taking folic acid, limiting caffeine and maintaining healthy weight, according to the National Institute of Child Health and Human Development (NICHD).

These are great tips, but there’s one thing that’s conspicuously absent — caring for the gut health of mom and her baby.

This first of a two-part series discusses the growing number of studies that show how promoting good gut health benefits moms before their babies are born.

Once upon a time

To appreciate the importance of the microbiome to the health of newborns, it’s important to understand that scientists believed — not so long ago — that the mother’s womb was a sterile environment, and babies acquired the beneficial bacteria needed to survive after they were born.

More recent studies have found the exact opposite: Babies may be “seeded” with beneficial bacteria important to their long-term health.

Although science is still figuring out how those healthy bacteria get to the unborn fetus via mom’s microbiome, many experts agree that exposure to bacteria does the both a world of good, from teaching the growing immune system how to recognize and handle pathogens to fighting diseases.

In fact, Dr. Josef Neu, a University of Florida pediatrician, is one of a growing number of experts who believe premature births can be reduced, merely by fetuses having healthy amounts of beneficial bacteria.

Even more important, should harmful bacteria attack the fetus, Dr. Neu and others believe an immune reaction is triggered sending the mother into premature labor, not good for the health of mom and her infant.

Dr. Neu’s solution, as told to the New York Times, is giving moms a “microbial cocktail,” something that sounds a lot like taking a probiotic. In this scenario, doctors could prescribe specific species to protect the fetus from infections or premature delivery.

Probiotics and preeclampsia

A huge concern all new moms have is bringing their babies into the world on time and with as few problems as possible.

Preeclampsia, a serious complication affecting blood pressure with damage to kidneys or other organs, is one of those obstacles that prevent a full-term birth, according to the Mayo Clinic.

The treatment of preeclampsia can be problematic. If left untreated, mom and her baby can face serious or fatal health consequences. The only “cure,” the Mayo Clinic says, is delivering a baby. But, what if that preeclampsia diagnosis comes too early in the baby’s fetal development?

Taking a daily probiotic may not cure preeclampsia. However, according to a 2011 study published in the American Journal of Epidemiology that monitored the health of more than 33,000 Norwegian women, probiotics lessened the risks of preeclampsia by up to 39 percent in some cases.

Taking a lactobacilli-laced probiotic every day was linked to a 20 percent decrease in the risk of preeclampsia, and a steeper 39 percent drop in a more severe form of the disease.

Scientists hypothesize that probiotics may lessen inflammation levels (a possible trigger for the disease) or have an effect on human placental trophoblasts (cells that form the outside layer of the blastocyst that provides nutrients to the embryo and develop into a large part of the placenta).

Bacterial warning signs

There’s more good news related to mom’s microbiome that may provide early warning signs of premature birth, according to preliminary research conducted by scientists from the University of Pennsylvania and University of Maryland.

Investigators took vaginal swabs from pregnant women during two time periods — late second trimester (20-24 weeks) and early third trimester (24-28 weeks) — then compared the kinds of bacteria (called community state type or CST) taken from moms who gave birth at full term versus those who gave birth prematurely.

“The percent of non-CST III was significantly lower in samples from women delivering preterm than term. Notably, the differences in these microbial communities were evident in the late second trimester of pregnancy, weeks if not months prior to the preterm birth,” said Dr. Michael Elovitz, director of the Maternal and Child Health Research Program at the Perelman School of Medicine at the University of Pennsylvania.

“This study is the first to report such key differences in the CV (cervicovaginal) microbial communities weeks prior to preterm birth. If differences in the CV microbial communities are confirmed, then new and exciting therapeutic strategies will emerge to prevent preterm birth.”

Although they weren’t identified as a strategy in this recent study, taking a multi-strain probiotic like EndoMune Advanced Probiotic remains the safest and easiest way a mom can give her baby a healthy head start.

Why more expecting mothers are taking probiotics Read More »

Treat colic safely, inexpensively with probiotics

Watching your young infant struggle with colic after feeding is among the most upsetting experiences you’ll face during the early months of his or her life. Fortunately, the prolonged crying and discomfort your baby experiences due to colic or other digestive ailments will be brief, particularly if you follow our recent list of 10 ways to calm your baby naturally and safely.

One of the easiest and safest ways to treat colic, and help your baby develop good gut health that boosts immunity, is taking a multi-species probiotic containing 5 to 10 billion CFUs (colony-forming units) per day.

A recent Italian study, published in JAMA Pediatrics, concluded giving healthy babies a daily dose of probiotics shortly after they’re born may lessen episodes of prolonged crying as well as the development of common gastrointestinal problems, including acid reflux and constipation.

Italian researchers assigned some 550 infants born at full term to receive either daily drops of a probiotic mixed with oil or a placebo (an oil mixture) for three months. Parents of those infants also kept diaries detailing any problems (inconsolable crying, bowel movements and vomiting) along with the number of visits made to their pediatrician.

The babies who received probiotics were obvious to spot by the end of the 90-day study.

  • The time babies treated with probiotics experienced prolonged crying was 38 minutes, or almost half the time (71 minutes) of the placebo group.
  • The probiotic group had more bowel movements (4.2) compared to those receiving a placebo (3.6).
  • The placebo group experienced more daily problems with regurgitations (4.6) than the probiotic group (2.9).

Interestingly, Italian scientists were also able to quantify the monetary benefits of giving babies a probiotic. Families saved $119 for each child given a probiotic.

“Driving a change of colonization during the first weeks of life through giving lactobacilli may promote an improvement in intestinal permeability,” according to the Italian researchers. “Visceral sensitivity and mast cell density and probiotic administration may represent a new strategy for preventing these conditions, at least in predisposed children.”

These results mirror similar findings in a 2007 study that concluded babies treated with a multi-species probiotic like EndoMune Advanced Junior cried about two-thirds less than those given the gas-reducing drug simethicone.

Treat colic safely, inexpensively with probiotics Read More »

EndoMune Interview: Dr. Josephine Ruiz-Healy

This week we’re kicking off an ongoing series of interviews with noted health care experts who consider good gut health essential in treating a wide variety of health issues.

Our first interview with Dr. Josephine Ruiz-Healy discusses the various gut health benefits probiotics provide children. Dr. Ruiz-Healy is a Clinical Associate Professor of Pediatrics at the University of Texas Health Science Center (UTHSC) at San Antonio. In private practice for two decades in San Antonio, she is Board Certified in Pediatrics and Integrative Holistic Medicine.

A relatively recent trend in American medical circles, integrative medicine focuses on treating the mind, body and spirit – at the same time by using the best of conventional and alternative therapies to facilitate the body’s innate healing responses, naturally and effectively.

Dr. Ruiz-Healy discusses how probiotics, good gut health and other integrative health tips can help babies get started on the right foot, along with avoiding antibiotics as often as possible.

Recent studies have reported mixed results about probiotics being an effective treatment for colic. Have you found probiotics to be helpful?

There has been mixed results in limited studies. The studies themselves show wide variability in their designs and parameters to offer definite results. However, it is a fact that infants with colic have a different intestinal microbiota than their “non-colicky” counterparts. Colicky infants have mainly coliforms that are not well colonized with Lactobacillus.

A different pattern is also seen in babies not colonized at birth who are born via Caesarean section and infants who are not breast-fed. We find the use of probiotics to be beneficial in some of our colicky babies who have these commonalities. Choosing the right probiotic is important. Not all are created equal and they all have different functions.

Multivitamins can cause constipation for some kids. Can probiotics and a healthy diet help?

We try not to use multivitamins that have iron if we do not need to supplement for this deficiency. But, without a doubt, trying to eliminate processed foods and over-cooked foods that indeed change your microbiota and substituting them with foods that have their own healthy biofilm and increasing their water consumption certainly change the microflora.

How do children benefit most from taking a probiotic?

Children are living in a toxic “artificial” environment now. That toxicity is interpreted by many scared parents as “too many germs” and not realizing we are more bacteria than human cells.

We try to eliminate everything that seems “contaminated.” We sterilize our homes but our children attend day cares where they get sick. Also, that illness in many instances is treated with antibiotics regardless if it is warranted or not, and kills the good bacteria in our gut further compromising our immunity.

Probiotics help fill that void we have because of life in the 21st century. A good blend of live probiotics seems essential to protect our kids and help them develop and maintain a healthy immune system.

What does good gut health mean for young children?

Good gut health translates to a good immunity.

There is research ongoing that the microbiota in infants is different for infants who develop allergic diseases, at all system levels. This is influenced by many external factors. We can change some of these factors by keeping, via the adequate mix of probiotics, a healthy gut microbiota.

When do you prescribe a probiotic to a young patient?

We recommend probiotics to infants who are bottle-fed, breast-fed infants whose mothers are on antibiotics or do not plan to breastfeed long, infants entering day care and fussy colicky infants who have no other underlying problems. It is essential children have a healthy gut microbiota before age 2!

Physicians are finally realizing the overprescribing of antibiotics is a serious health problem, although certain conditions require them. How do you advise parents?

Whenever we have children on antibiotics, we recommend probiotics rich in S. boulardi and we recommend they stay on them for at least a month before they change to a different mix of probiotics.

What other integrative health tips can you suggest to parents wanting to bolster their child’s gut health in addition to probiotics?

  • Avoid toxins!
  • Having parents understand that some fever is good for you and it is not a disease, and physicians taking the time to explain why not every time a child gets sick he/she needs antibiotics.
  • Give them vitamins every day.
  • Serve kids at least 6 servings per day of veggies and fruit, because it is the junk and processed foods that hurt them.
  • Decrease milk products.
  • Make kids get outside and play everyday.
  • Do not apply sunblock every time a kid goes outside. Let them get sunblock-free sun for at least 10 minutes.
  • Limit the time playing video games and watching TV.

EndoMune Interview: Dr. Josephine Ruiz-Healy Read More »

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