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Synbiotic Blend of 10 Beneficial Strains, Developed by Board-Certified Gastroenterologist

Best Probiotic Strain to Lose Weight and Increase Energy

Why it is important to have a specific strain of probiotic and a prebiotic to lose weight.

Most probiotics on the market contain correct strains of beneficial probiotic bacteria. However, even if the proper mix of probiotic bacteria are included in a probiotic supplement, they’ll never be effective unless they also contain a prebiotic. Prebiotics are plant fibers that can’t be digested by human digestive tracts. They move through the colon where probiotic bacteria use them for nutrition and growth. In other words, prebiotics are the food probiotic bacteria need to thrive, and create healthy guts so our bodies can achieve optimal health. These prebiotic plant fibers are found in foods like Apples, Bananas, Oatmeal, Wheat Bran, Barley, Onions, Asparagus, and Dandelion Greens.

There is a lot of misinformation (and misunderstanding) about how probiotics work in our bodies. For example, although probiotic bacteria are necessary for our bodies to both achieve and sustain optimum health, they don’t actually help our bodies directly, which I know sounds confusing. Let me explain. I described above that probiotic supplements require prebiotics to be effective, and here’s how that process works. Probiotic bacteria feed on the prebiotics, and in the process, the prebiotics (the indigestible plant fibers) are fermented.

This fermentation process produces several chemical byproducts, but the most important ones are short chain fatty acids (SCFAs). Short chain fatty acids provide energy to the cells in the colon. In fact, the number of certain kinds of SCFAs in your stool indicate the health of your gut microbiome, which is an indicator of your gut health. In other words, your gut can’t be healthy unless it contains the correct number of SCFAs.

Reduce your cravings and jump start losing weight.

Man doing a plank exercise on a yoga mat

The most important SCFAs in your gut are these:

  • Butyrate
  • Acetate
  • Propionate

Your gut manufactures these SCFAs by transforming plant fibers, starches, and carbohydrates into the three SCFAs listed above. Let’s examine briefly what each of these do, and how they affect gut health.

Cropped in photo of woman with illustrations of short chain fatty acid molecular structures overlaid on top of her


Butyrate is the most important energy source for the epithelial cells of the colon. But they also provide other key functions such as:

  • Producing healthy mucous in the lining of the gut
  • Alleviating discomfort in the gut
  • They suppress inflammation in the gut
  • Play an important role in suppressing the growth of cancer cells


Your gut produces more Acetate than any other short chain fatty acid, and it’s a critical compound to maintain a healthy gut. Acetate benefits gut health by:

  • Lowering pH to make your gut inhospitable to pathogens
  • Strengthening the Epithelial Barrier; absorbing nutrients and blocking pathogens

The Intestinal Epithelial Barrier regulates nutrient absorption, fights against pathogenic bacteria, and helps prevent many diseases such as idiopathic inflammatory bowel disease.


Propionate is another SCFAs produced in the gut from bacteria breaking down dietary fibers such as oat and wheat bran, cellulose, and other starches. The benefits of Propionate include:

  • Lowering cholesterol adsorption
  • Body-wide anti-inflammatory effects
  • Protecting against colon cancer

Importantly, Butyrate and Propionate both stimulate intestinal endocrine cells to release hormones that go to the appetite center in the brain, and suppress our appetite. If you want to lose weight, the importance of this process cannot be overstated. Here’s how that process, the satiety process our body requires to literally “make our stomachs feel full,” works.

These SCFAs induce your intestine to produce a hormone known as Glucagon-like peptide-1 (GLP-1). GLP-1 slows down the process where food leaves your stomach, which makes you feel full and triggers you to eat less. Beyond feeling full with less food intake – a necessary requirement to losing weight – this slower process of gastric emptying maximizes nutrient absorption while also limiting weight gain.

In other words, this is how your body makes you feel, reducing your craving to keep eating, which is a key factor to losing weight. Additionally, GLP-1 also signals to your pancreas to produce more insulin, which improves diabetes and decreases obesity.

EndoMune Metabolic Rescue contains the prebiotic xylooligosaccharide and the probiotic Bifidobacterium lactis, which helps your gut produce critical short chain fatty acids like butyrate and propionate exactly like I discussed above. In fact, in combination with a healthy diet, EndoMune Metabolic Rescue is a perfect way to jump start your weight loss journey today. Daily dosage is 4 capsules (2 capsules taken twice daily). To limit calorie intake, take 2 capsules 2 hours before larger meals or snacks.

1) Cell Metab.2018 April3;27(4)740-756
2) Hagmeyer Butyrate

Most individuals feel better in as little as seven days.

with your Physician

Before beginning a probiotic regimen, contact your physician to discuss any health concerns and if you are taking immunosuppressants or antifungals.

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