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Synbiotic Blend of 10 Beneficial Strains, Developed by Board-Certified Gastroenterologist
EndoMune Adult Probiotic Bottle

Doctor Formulated, Doctor-Approved.

Your Multi-Species Probiotic

Physician formulated EndoMune Probiotics contain 10 natural bacteria strains that naturally occur in healthy guts. These carefully selected bacteria help restore your gut health so it can work the way nature intended. In fact, they’ve been clinically tested in humans to be therapeutic to restore optimal GI health. Probiotics with 1 strain generally can’t do that compared to multi-species, multi-strain probiotics. If you have gut issues, EndoMune Probiotics can jump-start your journey to  better overall health – 100% naturally.

Only $42.95 for a two month supply – less than $0.72 cents a day.

EndoMune Ingredients

Amount Per Capsule % Daily Value
Total Cultures 30 Billion CFU*
Each EndoMune Advanced Probiotic capsule contains 30 Billion CFUs of a proprietary blend of the following bacteria specie strains:
  • Lactobacillus
    • Lactobacillus acidophilus,
    • Lactobacillus casei,
    • Lactobacillus plantarum,
    • Lactobacillus rhamnosus,
    • Lactococcus lactis,
  • Bifidobacterium
    • Bifidobacterium bifidum,
    • Bifidobacterium breve,
    • Bifidobacterium longum
    • Bifidobacterium lactis,
  • Streptococcus thermophilus

EndoMune Contains a Prebiotic

EndoMune is also a synbiotic because it also contains Fructooligosacchrides (FOS) which are non-digestible starches. FOS travels through the intestines where they nourish and support the growth of healthy bacteria your digestive tract needs to function the way nature designed it.  But FOS may also play another important role. According to Digestive and Liver Disease, FOS helps suppress Clostridium perfringens, a toxic bacteria associated with food poisoning. Another study reported in The Journal of Nutrition suggests FOS may also provide some protection against salmonella, another food-borne illness. For a complete list of benefits probiotics provide, look at the studies in the link at the bottom of this page.

Instructions for Use:

Take 1 capsule per day. Our improved advanced capsule design protects bacteria from gastric acid, so you can take at any time of day. However, to get the most benefit from EndoMune it’s best taken at the same time of the day. We suggest adding it to your daily ritual of eating a healthy breakfast.

EndoMune Advanced Probiotics for Your Whole Family

Naturally enhance your digestive health with our adult probiotic formula.

For a healthier gut, give your kids our doctor-developed, parent-approved probiotic.

Our proprietary probiotic supports healthy infant development.

Support natural weight loss and boost metabolism with our prebiotic/probiotic blend.

Research on Probiotic Selection and Use

The links to research and studies below provide references to many aspects and benefits attributed to taking probiotics. EndoMune provides these links so users can become more knowledgeable about probiotics, prebiotics, synbiotics and their use. Some of the topics discussed in the research below include the use of probiotics in general, and to prevent or treat five specific health conditions: atopic dermatitis, antibiotic-associated diarrhea, irritable bowel syndrome (IBS), hypercholesterolemia, and obesity.

Before taking any probiotic you are urged to consult with your physician.

  1. World Gastroenterology Organisation. Probiotics and prebioticsexternal link disclaimer. 2017.
  2. Zmora N, Zilberman-Schapira G, Suez J, Mor U, Dori-Bachash M, Bashiardes S, et al. Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features. Cell 2018;174:1388-405.e21. [PubMed abstract]
  3. Sanders ME. Probiotics in 2015: their scope and use. J Clin Gastroenterol 2015;49 Suppl 1:S2-6. [PubMed abstract]
  4. Sanders ME. Clinical use of probiotics: what physicians need to know. Am Fam Physician 2008;78:1026. [PubMed abstract]
  5. Kailasapathy K, Chin J. Survival and therapeutic potential of probiotic organisms with reference to Lactobacillus acidophilus and Bifidobacterium spp. Immunol Cell Biol 2000;78:80-8. [PubMed abstract]
  6. Szajewska H, Guarino A, Hojsak I, Indrio F, Kolacek S, Shamir R, et al. Use of probiotics for management of acute gastroenteritis: a position paper by the ESPGHAN Working Group for Probiotics and Prebiotics. J Pediatr Gastroenterol Nutr 2014;58:531-9. [PubMed abstract]
  7. Huang R, Ning H, Shen M, Li J, Zhang J, Chen X. Probiotics for the treatment of atopic dermatitis in children: a systematic review and meta-analysis of randomized controlled trials. Front Cell Infect Microbiol 2017;7:392. [PubMed abstract]
  8. Allen SJ, Martinez EG, Gregorio GV, Dans LF. Probiotics for treating acute infectious diarrhoea. Cochrane Database Syst Rev 2010:CD003048. [PubMed abstract]
  9. Freedman SB, Williamson-Urquhart S, Farion KJ, Gouin S, Willan AR, Poonai N, et al. Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis. N Engl J Med 2018;379:2015-26. [PubMed abstract]
  10. Ki Cha B, Mun Jung S, Hwan Choi C, Song ID, Woong Lee H, Joon Kim H, et al. The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Gastroenterol 2012;46:220-7. [PubMed abstract]
  11. Silverman MA, Konnikova L, Gerber JS. Impact of antibiotics on necrotizing enterocolitis and antibiotic-associated diarrhea. Gastroenterol Clin North Am 2017;46:61-76. [PubMed abstract]
  12. Blaabjerg S, Artzi DM, Aabenhus R. Probiotics for the prevention of antibiotic-associated diarrhea in outpatients-a systematic review and meta-analysis. Antibiotics (Basel) 2017;6. [PubMed abstract]
  13. Jafarnejad S, Shab-Bidar S, Speakman JR, Parastui K, Daneshi-Maskooni M, Djafarian K. Probiotics reduce the risk of antibiotic-associated diarrhea in adults (18-64 years) but not the elderly (>65 years): a meta-analysis. Nutr Clin Pract 2016;31:502-13. [PubMed abstract]
  14. Szajewska H, Kolodziej M. Systematic review with meta-analysis: Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea. Aliment Pharmacol Ther 2015;42:793-801. [PubMed abstract]
  15. Staudacher HM, Whelan K. Altered gastrointestinal microbiota in irritable bowel syndrome and its modification by diet: probiotics, prebiotics and the low FODMAP diet. Proc Nutr Soc 2016;75:306-18. [PubMed abstract]
  16. Zhuang X, Xiong L, Li L, Li M, Chen M. Alterations of gut microbiota in patients with irritable bowel syndrome: A systematic review and meta-analysis. J Gastroenterol Hepatol 2017;32:28-38. [PubMed abstract]
  17. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, et al. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol 2014;109:1547-61; quiz 6, 62. [PubMed abstract]
  18. Didari T, Mozaffari S, Nikfar S, Abdollahi M. Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis. World J Gastroenterol 2015;21:3072-84. [PubMed abstract]
  19. Lorenzo-Zuniga V, Llop E, Suarez C, Alvarez B, Abreu L, Espadaler J, et al. I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life. World J Gastroenterol 2014;20:8709-16. [PubMed abstract]
  20. Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, Barker ME, et al. Clinical trial: a multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study. Aliment Pharmacol Ther 2009;29:97-103. [PubMed abstract]
  21. McKenzie YA, Bowyer RK, Leach H, Gulia P, Horobin J, O’Sullivan NA, et al. British Dietetic Association systematic review and evidence-based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet 2016;29:549-75. [PubMed abstract]
  22. McKenzie YA, Thompson J, Gulia P, Lomer MC. British Dietetic Association systematic review of systematic reviews and evidence-based practice guidelines for the use of probiotics in the management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet 2016;29:576-92. [PubMed abstract]
  23. Ortiz-Lucas M, Tobias A, Saz P, Sebastian JJ. Effect of probiotic species on irritable bowel syndrome symptoms: A bring up to date meta-analysis. Rev Esp Enferm Dig 2013;105:19-36. [PubMed abstract]
  24. Bosch M, Fuentes MC, Audivert S, Bonachera MA, Peiro S, Cune J. Lactobacillus plantarum CECT 7527, 7528 and 7529: probiotic candidates to reduce cholesterol levels. J Sci Food Agric 2014;94:803-9. [PubMed abstract]
  25. Ishimwe N, Daliri EB, Lee BH, Fang F, Du G. The perspective on cholesterol-lowering mechanisms of probiotics. Mol Nutr Food Res 2015;59:94-105. [PubMed abstract]
  26. Cho YA, Kim J. Effect of probiotics on blood lipid concentrations: a meta-analysis of randomized controlled trials. Medicine (Baltimore) 2015;94:e1714. [PubMed abstract]
  27. Shimizu M, Hashiguchi M, Shiga T, Tamura HO, Mochizuki M. Meta-analysis: effects of probiotic supplementation on lipid profiles in normal to mildly hypercholesterolemic individuals. PLoS One 2015;10:e0139795. [PubMed abstract]
  28. Khalesi S, Bellissimo N, Vandelanotte C, Williams S, Stanley D, Irwin C. A review of probiotic supplementation in healthy adults: helpful or hype? Eur J Clin Nutr 2019;73:24-37. [PubMed abstract]
  29. Davis CD. The gut microbiome and its role in obesity. Nutr Today 2016;51:167-74. [PubMed abstract]
  30. Kadooka Y, Sato M, Ogawa A, Miyoshi M, Uenishi H, Ogawa H, et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. Br J Nutr 2013;110:1696-703. [PubMed abstract]
  31. Sanchez M, Darimont C, Drapeau V, Emady-Azar S, Lepage M, Rezzonico E, et al. Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. Br J Nutr 2014;111:1507-19. [PubMed abstract]
  32. Crovesy L, Ostrowski M, Ferreira D, Rosado EL, Soares-Mota M. Effect of Lactobacillus on body weight and body fat in overweight subjects: a systematic review of randomized controlled clinical trials. Int J Obes (Lond) 2017;41:1607-14. [PubMed abstract]
  33. Borgeraas H, Johnson LK, Skattebu J, Hertel JK, Hjelmesaeth J. Effects of probiotics on body weight, body mass index, fat mass and fat percentage in subjects with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials. Obes Rev 2018;19:219-32. [PubMed abstract]
  34. Suzumura EA, Bersch-Ferreira AC, Torreglosa CR, da Silva JT, Coqueiro AY, Kuntz MGF, et al. Effects of oral supplementation with probiotics or synbiotics in overweight and obese adults: a systematic review and meta-analyses of randomized trials. Nutr Rev 2019. [PubMed abstract]
  35. Dror T, Dickstein Y, Dubourg G, Paul M. Microbiota manipulation for weight change. Microb Pathog 2017;106:146-61. [PubMed abstract]
  36. AlFaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev 2014:Cd005496. [PubMed abstract]
  37. Hempel S, Newberry S, Ruelaz A, Wang Z, Miles JN, Suttorp MJ, et al. Safety of probiotics used to reduce risk and prevent or treat disease. Evidence Report/Technology Assessment number 200. Rockville, MD: Agency for Healthcare Research and Quality; 2011. [PubMed abstract]
  38. Bafeta A, Koh M, Riveros C, Ravaud P. Harms reporting in randomized controlled trials of interventions aimed at modifying microbiota: a systematic review. Ann Intern Med 2018;169:240-7. [PubMed abstract]
  39. Didari T, Solki S, Mozaffari S, Nikfar S, Abdollahi M. A systematic review of the safety of probiotics. Expert Opin Drug Saf 2014;13:227-39. [PubMed abstract]
  40. Borriello SP, Hammes WP, Holzapfel W, Marteau P, Schrezenmeir J, Vaara M, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003;36:775-80. [PubMed abstract]
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