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Probiotics

Probiotics, according to a large number of  studies indicate that probiotics help restore and maintain healthy guts leading to overall better health.

Probiotics and Post-Gastric Bypass Surgery Weight Loss

The July issue of the Journal of Gastroenterology discusses the recent findings of a post-gastric bypass surgery weightloss study. The physicians and researchers administering the study were interested in whether gastrointestinal bacteria and gut health plays an impact in the weight loss of individuals.

Both a control and a probiotic group were on the same counseling and diet regimen, with the probiotic group receiving 2.4 billion colonies of Lactobacillus daily.

At both 6-weeks and 3-months, the probiotic group had a statistically significant increase in weight loss over their counterparts in the control group. However, at 6-months, the significance had decreased.

With more research studies in the future, researchers may be able to determine if probiotics do have an impact on post-gastric bypass weight loss.

View the article at: http://www.medscape.com/viewarticle/706023

Pediatric Studies and IBS Research

Interest in probiotics and their healthful links to gastrointestinal ailments has spurred the recent launch of the National Institute of Health’s Human Microbe Project. Baylor College of Medicine in Dallas, Texas is heavily involved in many of these studies; they received $3.7 million to map human bacteria genome.

Most recently, Dr. James Versalovic, a genetecist with the college, received a $750,000 grant to research the impact of bacteria on IBS in pediatrics. His studies are expected to explore methods of treating children without the use of invasive surgery. Dr. Robert Shulman, a pediatrics professor at Baylor College of Medicine and a practicing gastroenterologist, believes bacteria composition plays a major role in adult and child abdominal pain.

This is all very exciting and interesting news in the intestinal bacteria and probiotic front!

Read the entire article from the Houston Chronicle:
http://www.chron.com/disp/story.mpl/metropolitan/6526164.html

Study on Antibiotic-Associated Diarrhea

A study recently published in the Journal of Medical Microbiology further explores the potential benefits of probiotics at maintaining intestinal health while ingesting antibiotics such as Augmentin.

The study concluded probiotics, particularly Bifidobacteria, may be helpful in returning to a pre-antibiotic baseline:

This study does identify a benefit of probiotics, in part through increasing Bifidobacterium that may limit the disruption of gut microbiota by antibiotics, stabilizing concentrations of Enterobactereaceae and Bacteroides in particular. While this does not represent a clinical end point in itself this study provides important insight into the nature of the disruption of gut microbiota by antibiotics and a possible mechanism whereby probiotics limit gastrointestinal adverse events associated with antibiotics.

Further studies are necessary to assess the clinical relevance of these observations.

Engelbrektson, Anna, et al. “Probiotics to minimize the disruption of feacal microbiotia in healthy subjects undergoing antibiotic therapy.” Journal of Medical Microbiology (2009), 58, 663-670.

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