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Probiotics + An Antidepressant = Gut-Brain Axis Relief

Probiotics + An Antidepressant = Gut-Brain Axis Relief

Are you taking an antidepressant to help you better manage your emotions, but finding that drug you’ve been prescribed isn’t working as well as it should?

That’s not unusual at all given that some 60 percent of patients with a major depressive disorder (MDD) experience some issues with first-line medicines, and about a third of patients continue to have problems after more treatments.

This may be a sign that your gut brain axis — the proven connection that links your brain, intestines and emotions — may need some extra help, especially if you’ve been diagnosed with an MDD.

Scientists at King’s College London came to a similar gut-based conclusion after conducting a pilot study that monitored the mental and physical health of MDD patients appearing in JAMA Psychiatry.


Multi-Strain Probiotics To The Rescue

A small group of 46 adult patients (primarily women ages 18-55) completed a trial that compared taking an antidepressant (mainly an SSRI drug) with a multi-strain probiotic or a placebo every day for eight weeks.

Interestingly, both probiotic and placebo groups experienced improvements in their symptoms, but the probiotic enjoyed even better results from week four to the end of the trial.

“The gut-brain axis is a truly fascinating and rapidly evolving area of microbiome research,” says study author Dr. Viktoiya Nikolova. “The findings of this pilot study are an important step forward in our understanding of the role of probiotics in mood and mental health.”

This isn’t the first time we’ve shared how effective multi-strain probiotics can be in relieving symptoms of depression, but it’s among the first to use them alongside antidepressants.

Interestingly, all but one of the strains of beneficial bacteria contained in EndoMune Advanced Probiotic were ingredients contained in the probiotic used in this study.

So, if you’re struggling with a MMD and are concerned it’s not working as it should, consider giving your gut-brain axis a gentle boost with the help of EndoMune.



JAMA Psychiatry

King’s College London

Neuroscience News

Nutraingredients Europe

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