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Digestive Health

Digestive Health related factors related to maintaining a healthy gut.

How Dietary Fiber Protects Your Health

Eating a variety of foods rich in dietary fiber – whole grains, legumes, vegetables and fresh fruits – is one of the best things you can do to protect your health from disease.

Unlike other components of food, dietary fiber isn’t broken down or absorbed. It passes through your body either as soluble fiber that dissolves in water and lowers cholesterol and glucose levels or insoluble fiber that helps food move through your digestive system.

Scientists at the University of California Davis (UC Davis) discovered another reason to eat more fiber based on how it interacts with your gut bacteria in ways that may protect your body from harmful pathogens, according to a recent study published in Science.

Here’s how it works: As the microbes in your gut process soluble fiber, short-chain fatty acids (better known as butyrate) are created which does a lot of good behind the scenes.

Ideally, butyrate signals to the cells lining the walls of your large bowel to increase its consumption of oxygen, protecting your gut from more harmful bacteria, like E. coli and Salmonella. (Butyrate production keeps gut inflammation in check too.)

Scientists better appreciated the work butyrate does when cells were exposed to antibiotics – definitely no friend to your gut. Antibiotics deplete your body’s reserves of butyrate, which reduces the signaling between butyrate and the gut wall.

This disruption in your gut’s natural signaling allows more oxygen to hang around, letting E. coli and other nasty bugs multiply. In time, all of these behind-the-scenes problems could come to the forefront and make you sick.

“Our research suggests that one of the best approaches to maintaining gut health might be to feed the beneficial microbes in our intestines dietary fiber, their preferred source of sustenance,” said Dr. Andreas Bäumler, professor of medical microbiology and immunology at UC Davis and senior author of the study, according to a press release.

Unfortunately, too many Americans are addicted to Western diets, full of fatty foods with little nutritional value, so they tend to avoid fiber-rich foods at the expense of their health.

That said, it doesn’t take a lot of fiber to make a big difference in your health. Merely increasing your intake of dietary fiber by just 1 ounce (about 30 grams) is enough to help you lose weight and lower your risk of cardiovascular problems, not to mention relieve constipation.

Boosting the amount of fiber you eat every day isn’t hard, especially if you like lentils, beans, artichokes, apples, pears, strawberries and whole grains.

Along with eating more fiber, taking a daily probiotic, like EndoMune Advanced Probiotic with multiple strains of beneficial bacteria and a prebiotic (FOS), may do even more good as both work in sync by triggering the fermentation process that feeds your gut safely and naturally.

How Dietary Fiber Protects Your Health Read More »

Probiotics will keep us Healthy in Space

The very last thing you’re probably thinking about when watching exciting science-fiction films like Interstellar or Gravity is the gut health of the astronauts flying through space.

But that doesn’t mean Earth-bound scientists aren’t studying or thinking about it… a lot!

Some of these studies could have some important real-world implications and benefits, even for the 99.99 percent of us who will never fly higher than 39,000 feet (slightly more than 7 miles) in the air.

The Twins Study

The most current and popular project has been the Twins Study, encompassing 10 NASA-funded studies that compared the molecular structures of identical twin astronauts: Scott Kelly who spent nearly a year in space living in a zero-gravity environment and his brother Mark who stayed on the planet as an “Earth-bound control subject.”

One of these research projects, based in Chicago at Northwestern University, Rush University Medical School and the University of Illinois, discovered some interesting fluctuations in the gut microbiomes of both brothers.

Researchers found imbalances in two dominant groups of bacteria (Bacteroidetes and Firmicutes) had shifted in Scott Kelly’s while space bound and returned to pre-flight levels after arriving back on Earth. Interestingly, Mark Kelly’s gut microbiome fluctuated in those two areas too, however, not as drastically as his twin.

Another very surprising result: An expected change in gut diversity while Scott Kelly was in space never happened.

Female astronauts need probiotics

A pair of Canadian researchers at Western University made a good case for female astronauts taking probiotics in a 2016 report appearing in the health journal Women’s Health.

Scientists believe the unique challenges female astronauts face — osteoporosis, breast cancer, compromised vaginal health and urinary tract infections (UTIs) — could be more problematic during space flights.

For instance, women experience more UTIs during space missions than their male counterparts. Treating women with antibiotics may be problematic due to gravity, not to mention the complications associated with overusing them, which is why researchers believe probiotics may be a better option.

“It’s important to look at the health of women,” said Carmilla Urbaniak, a Ph.D. candidate working at the school’s Schulich School of Medicine & Dentistry, according to a press release.

“We know that drugs interact differently in males and females. The impact of probiotics are also different between males and females, and it’s time we focused our research on female astronauts.”

Studying gut health on a microchip

Preventing disease isn’t the only concern on the minds of one lab funded by NASA at the University of Arizona’s Center for Applied NanoBioscience and Medicine.

Researchers there have created amazing “gut-on-a-chip” technology that mimics the internal workings of the human gut. Its primary function for this research is to test how the human gut will respond to cosmic radiation exposure during long periods of space travel.

Among the more practical applications for this microchip technology include the development of probiotics that could treat or even prevent radiation damage, says Dr. Frederick Zenhausen.

Don’t forget traveling on planet Earth

Back a bit closer to planet Earth, you may be traveling long distances in airplanes, especially over the long holiday season, to see family members far and wide.

Doing so creates opportunities for jet lag, a temporary sleep problem that happens when people travel quickly across multiple time zones.

These abrupt time shifts can also create problems for your gut, not only by messing up your body’s natural 24-hour circadian rhythms but playing a role in triggering the accumulation of body fat that leads to obesity.

Getting the right amount of sleep and eating a healthy, balanced diet goes a long way toward combating the effects of jet lag, but so does protecting the health of your gut.

Taking a probiotic with multiple strains of beneficial bacteria, like EndoMune Advanced Probiotic, every day gives your gut the extra protection it needs when traveling on land or in the air.

Probiotics will keep us Healthy in Space Read More »

Protect Your Gut From Fatty Holiday Foods

Many of us can’t wait for the end of the year, if for no other reason than to satisfy our year-round cravings for eggnog, prime rib, dressing, pecan pie and other fatty holiday foods.

Eating those holiday foods in excess as many of us do during the season comes with an unhealthy price to pay in adding extra pounds, not to mention harming our gut.

A recent study featured in Cell Reports goes a long way toward describing how the gut may predict the damage you do to your body merely by eating excessive amounts of high-fat foods.

High-fat diets: No ho, ho, ho!

Previous studies have found that people eating the same high-fat diets — the major culprit in an array of health problems, including diabetes, heart disease, obesity and stroke — react differently. Some may suffer from less or more problems than others.

Researchers fed genetically similar mice healthy foods and screened urine samples for compounds produced by their gut bacteria, establishing a baseline of healthy chemical profiles.

Once those same lab animals were switched to fatty foods, their tiny bodies reacted just like their human counterparts, with some becoming less tolerant to glucose (an early sign of diabetes) while others gained more weight.

Follow-up analyses of urine samples taken from mice after feeding them fatty foods changed too, predicting signs of unhealthy changes in weight, glucose and behavior.

In fact, the presence of one very popular chemical produced by the gut — trimethylene n-oxide (TMAO) — was a sign of glucose issues, not to mention heart disease.

“We tend to believe that obesity is caused by bad genes or by bad genes interacting with bad environment,” says Dr. Dominique Gauguier, a senior investigator on this study based in Paris, according to a press release.

“Our findings indicate that an organism’s gut microbiome can drive the adaptation to dietary challenges in the absence of genetic variation.”

These results are only the beginning, as researchers plan to embark on a larger, more in-depth clinical trial on 2,000 human patients that will go further toward forecasting how people react to differing diets and how gut health drives their overall health.

The long-term goal: Generating chemical profiles from urine and blood samples that may offer guidance on what diets are most supportive for a patient’s optimal health.

Until that comes…

What we do know right now is that maintaining a healthy balance of beneficial gut bacteria is critical in protecting your body from cardiovascular diseases like diabetes, based on the findings of a Danish study we’ve discussed previously.

That same study also found that patients who had less diverse gut microbiomes carried more fat on their bodies and experienced more inflammation in their digestive tracts, making them more vulnerable to cardiovascular diseases.

The holiday season is full of gatherings with friends, family and lots of fatty seasonal foods that can add inches and pounds to your waistline and disrupt the diversity of your gut in no time if you overindulge too often.

Keeping your portion sizes small and eating healthier foods rich in fiber can do a lot of good for your body and keep off those extra pounds.

Taking a multi-species probiotic, like EndoMune Advanced Probiotic with 10 distinct species of beneficial bacteria, can also go a long way toward protecting the diversity of your gut and your overall health too.

Protect Your Gut From Fatty Holiday Foods Read More »

Could Constipation Shut Down Your Kidneys?

As our understanding of the human gut grows, modern medicine has come to realize that constipation is a much more prevalent and serious health problem and far less benign that we ever realized.

In fact, constipation may be a symptom of greater health problems, from hormonal issues to diabetes, colon cancer and multiple sclerosis.

Add chronic kidney disease to that list of serious diseases, based on a recent study appearing in the Journal of the American Society of Nephrology.

Researchers at the University of Tennessee’s Health Science Center and Memphis Veterans Affairs Medical Center discovered the link as they studied and monitored the health of some 3.5 million veterans for nearly a decade.

Compared to healthy patients, those suffering from constipation were 13 percent more susceptible to chronic kidney disease, and 9 percent were more likely to develop kidney failure, necessitating dialysis treatments or a kidney transplant.

The link between constipation and chronic kidney disease may be an uncomfortable blessing in disguise, because there are few signs or symptoms in the early stages.

What’s more, a cluster of health problems ranging from diabetes and high blood pressure to obesity and heart disease can increase your risks of chronic kidney disease too, blurring that simple connection to constipation.

“Our results suggest the need for careful observation of kidney function trajectory in patients with constipation, particularly among those with more severe constipation,” says Dr. Csaba Kovesdy, chief of nephrology at the Memphis Veterans Affairs Medical Center, according to a press release.

Right now, constipation is nothing more than a warning sign of chronic kidney disease. However, if constipation is found to play a more active role in this disease based on future research, Dr. Kovesky believes simple lifestyle adjustments and taking a probiotic may be enough to protect a patient’s kidney health.

Taking a probiotic with multiple species of beneficial bacteria like EndoMune Advanced Probiotic is a safe, proven way to boost the healthy diversity of your gut microbiome to treat constipation safely, effectively and without a drug.

Could Constipation Shut Down Your Kidneys? Read More »

Do You Live in a Hurricane Zone? Take Your Probiotics!

Despite all of the modern conveniences we enjoy in America, the safety of our nation’s food and water supplies remains a consistent problem due to contamination from nasty strains of bugs like Escherichia coli, better known as E. coli bacteria.

Most strains of E. coli are common and relatively benign, especially those living in the guts of animals and humans. However, the most popular strain of E. coli — Shiga toxin-producing E. coli (STEC) — seems to find its way into our food and water more often these days due to unforeseen contamination.

More than 250,000 Americans are sickened annually as a result of contact with the STEC form of E. coli, according to the CDC.

Many who come in contact with this sickening kind of E. coli usually suffer from watery diarrhea, gas and severe abdominal cramping, but it passes within 10 days.

Yet one very serious health problem related to E. coli infections reported in previous food outbreaks, hemolytic uremic syndrome (HUS), can destroy red blood cells and may lead to kidney failure if not treated quickly and appropriately.

E. coli concerns have risen to new levels over the past few weeks with Hurricanes Harvey and Irma slamming into the coasts of Texas and Florida, respectively, destroying homes and property along the Atlantic and Gulf Coasts (with more on the way).

How bad is it?

Some Houston neighborhoods were slammed by E. coli contamination after rains from Hurricane Harvey flooded local sewage plants, according to reports in the New York Times and Houston Public Media.

In fact, area scientists measured E. coli levels in one Houston home exceeding 135 times beyond what’s considered safe.

The problem: Warm temperatures coupled with stagnant water that’s trapped inside a flooded home and tainted with sewage can become a safe haven for bacteria multiplying at a much faster rate than it would outdoors, creating massive health problems.

The same kind of damage with sewage overflows has been reported all over the Florida peninsula, with spills reported from Miami to Jacksonville due to Hurricane Irma, according to New Republic.

The bad bugs swimming in Florida waters may have exposed residents to noroviruses that people encounter on cruise ships and other nasty pathogens, such as giardia and salmonella, says Dr. Valerie Harwood of the University South Florida.

Unfortunately, your town doesn’t have to be hit by a hurricane to have a problem with E. coli. Residents of Atlantic Beach, N.C., recently experienced this problem when local officials ordered a boil order for 24 hours due to E. coli found in a local water sample, according to Food Safety News.

And, that’s just one bacteria…

Exposure to Vibrio vulnificus from coastal flooding via hurricanes also creates the rare but deadly possibility for harmful infections that harm those with open wounds who could lose limbs or even die.

In fact, open wounds and scrapes infected with Vibrio can worsen in just 10 hours to the point that limbs may require amputation, experts say.

Take these steps to protect your health

If you live in the harm’s way of natural disasters like hurricanes or severe storms that flood your home, there are simple steps you can take to protect the health of you and your family.

  • If you have an open wound, avoid any exposure to flood waters, and seek medical attention quickly if it worsens.
  • Wash your hands with warm, clean water and plain soap if you have to return to your home to do repairs or pick up clothing, especially before meals. Skip antibacterial cleaning products that create opportunities for more powerful superbugs.
  • Don’t allow your children to play with toys that have been floating in dirty floodwater, until they have been disinfected.
  • Are you current on your vaccinations? Call your doctor!
  • Don’t skip taking a daily probiotic, ideally one containing multiple strains of beneficial bacteria like EndoMune Advanced Probiotic, as it gives your immune an extra boost that protects your health from E. coli and other nasty bugs.

Do You Live in a Hurricane Zone? Take Your Probiotics! Read More »

Why Do I Need to Take a Probiotic?

For people who are reading our blog for the very first time or those needing a refresher course in good gut health habits, you may be wondering why we devote so much space to explaining why you need to take a probiotic.

There are A LOT of reasons for taking probiotics, in addition to promoting good gut health! Fortunately, you don’t have to do the research.

What follows are 10 important reasons why you should be taking probiotics for your good health, based on the latest research.

  1. Many cheap brands of probiotics contain a single strain of beneficial bacteria, which may be good for a specific problem. However, a multi-strain probiotic protects the diversity of your gut and treats common gut health problems like constipation too.
  1. Do you use an over-the-counter medication like loperamide (Imodium) to treat a case of diarrhea? Taking a probiotic is one of the most effective ways, not only to get rid of diarrhea, but to prevent it altogether.
  1. Irritable bowel syndrome (IBS) can do great harm to your gut and your emotions, disrupting your body’s gut-brain axis. Taking a probiotic and a prebiotic (EndoMune Advanced Probiotic and Endomune Jr. Probiotics for Kids contains both) may be a good way to treat IBS and depression without a drug.
  1. Are you taking antibiotics more than once a year to treat persistent infections? Antibiotics rapidly deplete the beneficial bacteria and make you more vulnerable to serious diseases such as colon cancer and more serious antibiotic-resistant infections. Taking a daily probiotic gives your body extra protection by replenishing the beneficial bacteria your body needs.

(You’ll also do your health a great deal of good by avoiding contact with antibacterial soaps that contain broad spectrum and synthetic antimicrobial compounds like triclosan too.)

  1. For patients who suffer from migraines, scientists have recently discovered a link between those painful headaches and nitrates, a common food additive. Some gut health experts believe taking a probiotic may become a safer, non-drug answer to treat migraines.
  1. Have problems with your teeth? Taking a probiotic is good treatment, as it may be a one more way to heal chronic periodontitis and reduce inflammation and levels of gingivitis and plaque, in addition to regular dental care.
  1. Hypertension can be a warning sign of serious health problems behind the scenes and even death. Taking a daily probiotic can improve your overall health, lower your blood pressure safely and lessen your dependence on prescription medications.
  1. Do you fly for your job or pleasure on a frequent basis or work a swing shift? The balance of bacteria in your gut is affected your body’s circadian rhythms as you cross time zones — often due to jet lag — but taking a probiotic prevents that yo-yo effect from harming your health.
  1. Protecting your sleep is an important part of restoring your body night after night. Be sure that any probiotic you consider taking also contains a prebiotic that can help you improve your sleep.
  1. Are you a new parent losing sleep over your baby’s prolonged crying due to colic? A number of studies point to probiotics as a safe, healthy way to lessen colic and prevent other common problems for babies like acid reflux and constipation.

Why Do I Need to Take a Probiotic? Read More »

Your Gut Bacteria Have a 24-Hour Routine

Messing up your body’s circadian rhythms — the behavioral, mental and physical changes that follow a 24-hour cycle — can have a huge effect on your health and gut.

Merely traveling on an airplane across multiple time zones can trigger jet lag, a temporary sleep problem when your body’s internal rhythms and biological clock are out of sync.

Apparently, your gut bacteria have a circadian schedule too, and a pair of studies shows how they affect your health for better and worse.

Following a schedule

Research by scientists at the Weizmann Institute of Science on mice in a study appearing in Cell demonstrated how gut bacteria follow a schedule, adapting to changes in light and dark, metabolic fluctuations and even the timing of our meals, says Dr. Eran Segel.

In fact, your microbiome moves around within the gut and are exposed to different species and varying numbers of species over the course of a 24-hour day.

Moreover, those changes brought on by circadian rhythms affect not only the physiology of the body but tissues and organs like the liver. Those rhythms can even govern how your body may metabolize and detoxify a drug as basic as acetaminophen.

Scientists also learned how the circadian rhythms of the bodies of little mice (and perhaps humans too) are very dependent on the workings of the microbiome. Surprisingly, genes that show no signs of circadian rhythms take over when these microbial rhythms are disrupted too.

These findings were observed when researchers gave mice antibiotics that removed much of their gut bacteria and even when their feeding times were changed.

Circadian rhythms and obesity

This inter-dependence between the gut and the body’s circadian rhythms could play a role behind the scenes in promoting the accumulation of body fat that leads to obesity, according to a recent study conducted at the University of Texas Southwestern and published in the journal, Science.

Based on tests that compared the health of germ-free, conventionally raised and genetically modified mice, scientists learned how the microbiome controls fat uptake and storage by “hacking into” and altering the functions of the circadian clocks within cells that line the gut.

They identified the mechanism by which gut bacteria regulate the composition of body fat and use a chemical (circadian transcription factor NFIL3) to establish a critical molecular link between the microbiota, circadian clock and metabolism, says Dr. Lora Hooper, lead author of the study, according to a press release.

So how does the microbiota hack into the lining of the gut?

A body’s circadian clock senses those day and night cycles, which are linked closely to feeding times, and transmits that information to the gut to turn on and off the metabolism (the uptake of lipids) when necessary.

More specifically, the circadian rhythms of the gut control the expression of NFIL3 and the production of lipids that are governed by this chemical in the intestinal lining.

“So what you have is a really fascinating system where two signals from the environment come in – the microbiome and the day-night changes in light – and converge on the gut lining to regulate how much lipid you take up from your diet and store as fat,” says Dr. Hooper.

How does this affect you?

Our go-go-GO! lifestyles create all sorts of havoc with our sleep schedules and often distract us from eating healthy meals on a timely basis, creating an environment for all sorts of health problems down the line.

Eating a balanced diet and getting the right amount of sleep your body needs every night really matters. And, we’ve learned in these studies, so does the health of the human gut, especially if you do a lot of traveling or work a crazy schedule that mixes daytime and nighttime hours.

That’s why it’s so important to give the health of your gut an added boost by taking a multi-species probiotic, like EndoMune Advanced Probiotic, that features 10 proven and protective strains of beneficial bacteria and a prebiotic that feeds the good bugs and may improve your sleep too!

Your Gut Bacteria Have a 24-Hour Routine Read More »

Treating IBS-Related Depression With Probiotics

Most symptoms associated with irritable bowel syndrome (IBS) — gas, cramping, diarrhea and constipation — are very uncomfortable, very embarrassing and very painfully obvious.

Considering the pain and discomfort you may be feeling, however, you may not be paying as much attention to one specific symptom — depression — as it really deserves.

Plus, taking drugs like mesalazine may be good for treating some IBS symptoms, but they don’t address the real problem: Restoring a healthy balance of bacteria in the gut.

Not only can taking a probiotic be a safer way to restore and protect that gut bacteria balance, it may also treat the symptoms of depression associated with IBS too, according to a recent study published in Gastroenterology.

Researchers at McMaster University in Canada studied the effect that prescribing a probiotic formulated with a proprietary blend of Bifidobacterium longum (one of the 10 species of beneficial bacteria found in EndoMune Advanced Probiotic) has on treating depression.

Over the course of 10 weeks, scientists monitored the health of 44 patients, half of whom took a probiotic while the rest were given a placebo.

After just six weeks, nearly two-thirds of patients in the probiotic group felt greater relief from their depression based on falling scores based on the standard Hospital Anxiety and Depression Scale (HADS), versus just seven in the placebo group.

More evidence that those falling HADS scores were real: Functional Magnetic Resonance Imaging tests that showed changes in various sectors of the brain related to mood control.

Other good things could be taking place behind-the- scenes that moderate your mood levels, thanks to probiotics. For example, as much as 90 percent of your body’s serotonin, a chemical that works as a neurotransmitter in the brain, is produced in the gut.

Taking a probiotic is one important and safe way to protect and enhance the diversity of beneficial bacteria in your gut naturally, without a drug.

Treating IBS-Related Depression With Probiotics Read More »

Multi-species probiotics conquer constipation

All by itself, constipation is a serious health problem accounting for some 2.5 million visits to American doctors, not to mention a growing number of trips to the ER. Constipation is also one of the telltale symptoms of irritable bowel syndrome (IBS), a chronic condition that affects the colon.

In the past, people have attempted to treat their IBS symptoms with drugs like mesalazine and mexiletine with only mixed results and a lot of unwanted side effects.

The real problem with taking these kinds of drugs is that they don’t get to the root cause of the problem: Rebuilding the healthy balance of beneficial bacteria in the gut.

Taking a multi-species probiotic can do a great deal of good, not only in restoring that gut healthy balance, but treating IBS symptoms associated with constipation too, according to a recent Italian study appearing in BioMed Research International.

For their randomized, double-blind study, scientists divided 150 IBS patients (all adults between age 18-65) with constipation issues into three groups, including one who received a placebo, for 60 days.

Interestingly, three of the five strains of beneficial bacteria in the multi-species probiotic given to patients — blends of Lactobacillus rhamnosus, Lactobacillus plantarum and Lactobacillus acidophilus — are contained in EndoMune Advanced Probiotic.

Compared to the placebo group, the major symptoms of IBS patients taking a multi-species probiotic improved from 74-82 percent compared to just 40 percent for the placebo group.

Even better, patients in both probiotic groups enjoyed relief from symptoms 30 days after the end of supplementation. In fact, signs of some beneficial bacteria were present in stool samples taken from patients too.

This study provides more evidence that taking a probiotic can be a much safer, healthier solution for treating constipation, especially the variety connected with IBS and a lot of other gut-related problems.

Again, the real trick is taking a probiotic made with multiple strains of bacteria from three key “families” (plus a prebiotic) like EndoMune Advanced Probiotic that supports the diversity of bacteria that inhabit your gut.

Multi-species probiotics conquer constipation Read More »

Can excessive exercise promote leaky gut?

The benefits from regular exercise — from reducing your risks to catastrophic conditions like cancer, type 2 diabetes and cardiovascular disease to improving your brain — are many and varied. In fact, a very popular Lancet study argued the lack of regular exercise could be as deadly to your health as smoking.

But, what happens when you take exercise to the opposite extreme? Overdoing anything often reverses much of the benefits you might’ve achieved in moderation, and exercise is no exception.

Based on a 2015 study published in the Journal of the American College of Cardiology, people who exercised more than four hours a week had virtually the same risk of dying as sedentary folks who rarely exercised.

A pair of very recent scientific reports have also tied excessive exercise to serious health problems that may promote leaky gut, a disorder in which a breakdown in the intestinal wall allows unintended substances — undigested food, toxic waste products, bacteria and viruses — to seep through the intestinal barrier and into the bloodstream.

Extreme exercise may harm your gut after 2 hours

Exercising for two hours at 60 percent of the maximum volume of oxygen an athlete can use (VO2 max) along with stress felt from excess heat pushed patients into an unhealthy state, based on a review of studies featured in Alimentary Pharmacology and Therapeutics.

How does that happen? If a patient’s gut loses a lot of blood during exercise, medical experts speculate the resulting inflammation can leave its protective lining damaged. In this vulnerable state, an ideal environment is created for leaky gut.

This review also determined that low to moderate exercise may be beneficial for patients suffering from irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD).

Lengthy military training may harm the gut too

Prolonged exercise was a trigger for leaky gut in a second study appearing in the American Journal of Physiology — Gastrointestinal and Liver Physiology.

In this study, military scientists from Norway, the U.S. Army and the Geneva Foundation as well as the Frederick National Laboratory for Cancer Research tracked the health of 73 Norwegian Army soldiers training in cross country skiing for four days. During that time, soldiers skied 31 miles while carrying 99-pound backpacks.

Researchers collected blood and fecal samples before and after the exercise. Before giving urine samples on the first and third days of training, soldiers drank a mix of water and sucralose and mannitol (an artificial sugar and a sugar alcohol, respectively) to detect signs of leaky gut.

By the end of the training period, the collective gut health of these soldiers as well as the composition of substances in blood and stool samples taken from them changed significantly and for worse. The excretion of sucralose rose greatly too, indicating an increase in leaky gut.

Multi-species probiotics do make an impact

Despite the good probiotics do, some scientists believe they may not do much to protect gut permeability. However, a 2012 report from the Journal of the International Society of Sports Nutrition that tracked the health of 22 trained athletes taking multi-species probiotics proved otherwise.

The key takeaway: The production of zonulin — an inflammatory protein that regulates leakiness in the gut — decreased slightly from levels slightly above normal to normal ranges, then dropped significantly after 14 weeks of supplementation with multi-species probiotics.

There are times when the leakiness triggered by zonulin protects your body in healthy ways, experts say, when you eat foods contaminated with harmful bacteria. When that happens, zonulin reacts by triggering diarrhea to get rid of the bad bugs.

Not only is taking a probiotic with multiple strains of beneficial bacteria like EndoMune Advanced Probiotic an ideal way to shorten the duration of diarrhea, this non-drug treatment gives your body a much needed boost to its natural defenses and may offer some protection from leaky gut too.

Can excessive exercise promote leaky gut? Read More »

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