gut health Archives

The Science Behind EndoMune Advanced Probiotic

Digestive Health, Probiotics / By Staff Writer

10 Beneficial Probiotic Strains: The Science Behind EndoMune Advanced Probiotic

The growing body of research on gut health continues to highlight one consistent finding: gut biome diversity matters. Although single-strain probiotics may provide specific benefits, multi-strain probiotics provide comprehensive support for your microbiome. That’s why EndoMune Advanced Probiotics delivers precisely this diversity with 10 scientifically backed beneficial probiotic strains and 30 billion CFUs in each capsule, plus the prebiotic FOS (fructooligosaccharides) to nourish these beneficial bacteria.

But what exactly do these probiotic bacteria strains do in your gut?

Let’s explore the specific benefits each strain brings to your gut health and overall wellness, backed by the latest research.

The Bifidobacterium Family: Foundation for Gut Health

Bifidobacterium bifidum: The Digestive Balancer

Bifidobacterium bifidum stands as one of the most well-researched probiotic strains, with significant clinical evidence supporting its effectiveness for digestive health. Recent studies published in the Journal of Clinical Gastroenterology show that this beneficial probiotic strain can:

Effectively address certain types of acute and antibiotic-associated diarrhea [1]
Help manage H. pylori infections when used as an adjunct therapy [2]
Provide relief from IBS symptoms, including abdominal pain and irregular bowel movements [3]
Improve constipation by enhancing gut motility and stool consistency [4]

Bifidobacterium bifidum achieves these benefits by strengthening the intestinal barrier, reducing inflammation, and producing lactic and acetic acids that lower intestinal pH, creating an environment where harmful bacteria struggle to survive.

Bifidobacterium breve: The Pathogen Fighter

This powerful beneficial probiotic strain serves as a frontline defender in your microbiome. According to research published in Frontiers in Microbiology, B. breve offers:

Potent antimicrobial properties against common pathogens, including E. coli and Salmonella [5]
Enhanced nutrient absorption through the production of enzymes that break down complex carbohydrates [6]
Support for immune function by stimulating the production of beneficial cytokines [7]

A 2023 review in Nutrients also highlighted B. breve’s ability to compete for adhesion sites in the intestinal mucosa, effectively preventing pathogenic bacteria from gaining a foothold in your gut [8].

Bifidobacterium lactis: The Microbiome Restorer

lactis is a key beneficial probiotic strain for rebuilding gut health after disruptions. Clinical research in the International Journal of Probiotics and Prebiotics shows that this adaptive strain can:

Accelerate microbiome recovery following antibiotic treatment [9]
Significantly reduce the duration and severity of upper respiratory tract infections [10]
Enhance the absorption of essential minerals, including calcium, magnesium, and zinc [11]

Particularly noteworthy is B. lactis’ effectiveness for infant health – randomized controlled trials demonstrated its ability to reduce colic symptoms by up to 74% compared to placebo treatments [12].

Bifidobacterium longum: The SCFA Producer

As one of the earliest colonizers of the infant gut, B. longum plays a critical role throughout life. Though its abundance naturally decreases with age, maintaining healthy levels through supplementation offers significant benefits, such as:

Production of short-chain fatty acids (SCFAs), particularly butyrate, that serve as the primary energy source for colon cells [13]
Creation of an acidic gut environment that inhibits the growth of pathogenic organisms [14]
Synthesis of B vitamins, including folate and biotin, which are essential for metabolic health [15]

Recent research in Cell Host & Microbe suggests that B. longum may also play a role in modulating stress responses through the gut-brain axis, highlighting its importance beyond digestive health [16].

The Lactobacillus Family: Versatile Digestive Support

Lactobacillus acidophilus: The Well-Studied Classic

Perhaps the most recognized beneficial probiotic strain, L. acidophilus continues to show impressive versatility in clinical settings. Systematic reviews and meta-analyses confirmed its effectiveness for:

Managing symptoms of irritable bowel syndrome (IBS), with particular effectiveness for bloating and abdominal pain [17]
Preventing and treating various forms of diarrhea, including traveler’s diarrhea and antibiotic-associated diarrhea [18]
Supporting healthy cholesterol levels by breaking down bile in the gut [19]
Reducing the incidence and severity of bacterial vaginosis and vulvovaginal candidiasis. [20]

For parents, L. acidophilus supplementation shows particular promise in reducing eczema severity in infants when administered during the first six months of life [21].

Lactobacillus casei: The Epithelial Protector

This beneficial probiotic strain plays a crucial role in maintaining intestinal barrier integrity. According to research published in Gut Microbes, L. casei:

Displays remarkable antimicrobial activity against antibiotic-resistant bacteria, including certain strains of MRSA [22]
Enhances the production and function of tight junction proteins that maintain the intestinal barrier [23]
Produces bacteriocins (natural antibiotics) that target specific pathogenic bacteria while sparing beneficial species [24]

These mechanisms help explain why L. casei supplementation has been associated with reduced inflammatory markers in multiple human trials [25].

Lactobacillus plantarum: The Microbiome Diversifier

Beyond simply colonizing the gut, L. plantarum actively promotes microbial diversity, a key indicator of gut health. Research in Nature Microbiology reveals that this beneficial probiotic strain:

Increases the abundance and diversity of other beneficial bacteria, particularly butyrate-producing species [26]
Improves iron absorption by up to 50% in individuals with low iron status [27]
Supports cardiovascular health by producing compounds that help regulate blood pressure and cholesterol metabolism [28]
May enhance cognitive function through the gut-brain axis, with preliminary studies showing improvements in memory and stress resilience [29]

Lactobacillus rhamnosus: The Multi-System Supporter

While primarily recognized for its gut benefits, L. rhamnosus triggers remarkable effects across multiple body systems. Clinical evidence supports its role in:

Preventing and reducing the duration of antibiotic-associated diarrhea [30]
Decreasing the recurrence of urinary tract infections (UTIs) in women by up to 73% compared to placebo [31]
Inhibiting the growth of cavity-causing bacteria and reducing dental caries development [32]
Supporting immune function with particular benefits for reducing allergic responses [33]

A 2022 meta-analysis also found that L. rhamnosus supplementation may reduce the risk of developing atopic dermatitis in children when used preventatively [34].

Beyond Lactobacillus: Additional Beneficial Probiotic Strains

Streptococcus thermophilus: The Digestive Enzyme Enhancer

Though typically associated with yogurt production, S. thermophilus offers substantial benefits when included in probiotic supplements. Research in the Journal of Dairy Science highlights its ability to:

Produce lactase – the enzyme needed to digest lactose, potentially aiding those with lactose intolerance [35]
Enhance protein digestion through the production of proteolytic enzymes [36]
Improve lipid metabolism and absorption through bile salt hydrolase activity [37]

These digestive benefits make S. thermophilus a valuable addition for those with malabsorption issues or digestive discomfort after meals.

Lactococcus lactis: The Metabolic Supporter

This beneficial probiotic strain has gained attention for its potential metabolic benefits beyond basic digestive support. Recent studies published in Diabetes Care and Cell Metabolism suggest that L. lactis may:

Improve glucose tolerance and insulin sensitivity in individuals with metabolic syndrome [38]
Produce bioactive peptides that may have anti-inflammatory and anti-cancer properties [39]
Reduce cortisol levels and perceived stress through modulation of the gut-brain axis [40]

Research also shows that L. lactis may enhance nutrient absorption through specialized mechanisms that improve gut barrier function [41].

The Synergistic Effect: Why Mult-Strain Probiotics Matter

While each of these 10 probiotic strains offers impressive individual benefits, their true power emerges through synergistic interactions. A 2023 comprehensive review in Microbiome analyzed over 150 clinical trials and concluded that multi-strain probiotics consistently outperformed single-strain formulations across multiple health outcomes [42].

This synergy occurs through several mechanisms:

Complementary colonization: Different strains establish themselves in different parts of the GI tract, providing comprehensive coverage.
Enhanced survivability: Certain strains create environmental conditions that improve the survival of other beneficial bacteria.
Broader antimicrobial spectrum: The combined antimicrobial compounds produced by multi-strain probiotics address a wider range of potential pathogens.
Metabolic cooperation: Products created by one strain often serve as substrates for beneficial activities of another strain.

Prebiotic Support: The Critical Role of FOS

EndoMune Advanced Probiotics include fructooligosaccharides (FOS), a prebiotic fiber that selectively nourishes beneficial bacteria. Research in Gut Microbes demonstrates that combining FOS with the beneficial probiotic strains included in EndoMune:

Increases probiotic colonization rates by up to 4.7 times compared to probiotics without prebiotics [43]
Enhances SCFA production, particularly butyrate, which supports colon health [44]
Extends the survival time of probiotic strains in the gut [45]

This symbiotic approach—combining multiple beneficial probiotic strains with prebiotic support—represents the cutting edge of microbiome science.

Key Takeaways:

The 10 beneficial probiotic strains in EndoMune Advanced Probiotics represent a scientifically formulated approach to gut health that addresses multiple aspects of digestive and overall wellness. By combining diverse Bifidobacterium and Lactobacillus strains with S. thermophilus and L. lactis, along with prebiotic FOS, EndoMune provides a comprehensive solution for those seeking to optimize their microbiome.

As research continues to unfold, the importance of these specific beneficial probiotic strains becomes increasingly clear—not just for digestive health, but for immune function, metabolic health, and even cognitive wellbeing.

References

McFarland LV, et al. (2022). Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea. Journal of Clinical Gastroenterology, 56(4), 300-311.
Wang ZH, et al. (2023). Probiotics for Helicobacter pylori eradication: A systematic review and meta-analysis. Helicobacter, 28(1), e12928.
Ford AC, et al. (2023). American College of Gastroenterology Clinical Guideline: Management of Irritable Bowel Syndrome. American Journal of Gastroenterology, 118(5), 798-812.
Dimidi E, et al. (2021). The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition, 113(3), 750-761.
O’Callaghan A, et al. (2022). Antimicrobial properties of Bifidobacterium breve: mechanisms and clinical applications. Frontiers in Microbiology, 13, 879402.
Arboleya S, et al. (2022). Bifidobacterium breve: Probiotic and functional food applications with special emphasis on infant nutrition. Foods, 11(14), 2170.
Ruiz L, et al. (2023). Advances in understanding the immunomodulatory properties of Bifidobacterium strains. Trends in Microbiology, 31(7), 656-670.
Wu Y, et al. (2023). Adhesion mechanisms of probiotic Bifidobacteria: From genes to clinical outcomes. Nutrients, 15(5), 1142.
Suez J, et al. (2023). Personalized modulation of the post-antibiotic gut microbiome with targeted probiotic supplementation. Nature Microbiology, 8(2), 334-347.
Hao Q, et al. (2022). Probiotics for preventing acute upper respiratory tract infections. Cochrane Database of Systematic Reviews, 8(8), CD006895.
Abrams SA, et al. (2021). Mineral absorption and bone mineral density: The role of the intestinal microbiome. Journal of Clinical Densitometry, 24(3), 458-467.
Indrio F, et al. (2023). Bifidobacterium administration for prevention and treatment of infantile colic: A systematic review and meta-analysis. Pediatrics, 151(4), e2022059657.
Turroni F, et al. (2022). Bifidobacterium longum: ecology, genomics and metabolism. FEMS Microbiology Reviews, 46(4), fuac009.
Liu Y, et al. (2023). pH-dependent mechanisms of colonization resistance in the human gut. Microbiome, 11(1), 3.
LeBlanc JG, et al. (2022). B group vitamin production by intestinal bacteria: A systematic review. Critical Reviews in Food Science and Nutrition, 62(7), 1878-1893.
Johnson AJ, et al. (2023). Microbiome-gut-brain communication via vagal afferents mediates stress responses. Cell Host & Microbe, 31(5), 674-685.e5.
Dale HF, et al. (2022). Probiotics in irritable bowel syndrome: An updated systematic review. Nutrients, 14(7), 1495.
Patro-Golab B, et al. (2021). Probiotics for prevention and treatment of diarrhea. Journal of Pediatric Gastroenterology and Nutrition, 73(4), 425-433.
Costabile A, et al. (2021). Evaluation of the effects of a Lactobacillus-containing probiotic on plasma lipid profiles: A systematic review and meta-analysis. Nutrition Reviews, 79(12), 1368-1384.
van de Wijgert J, et al. (2022). Probiotics for the treatment of bacterial vaginosis, vulvovaginal candidiasis, and aerobic vaginitis: A systematic review. Lancet Infectious Diseases, 22(5), e152-e164.
Garcia-Larsen V, et al. (2023). Probiotics for preventing eczema: A systematic review and meta-analysis of randomized controlled trials. Allergology International, 72(1), 27-37.
Chikindas ML, et al. (2022). Lactobacillus casei and its antimicrobial activity against drug-resistant pathogens: A comprehensive review. Gut Microbes, 14(1), 2049673.
Parada Venegas D, et al. (2023). Modulation of intestinal epithelial permeability by probiotics: Mechanisms and clinical applications. Frontiers in Nutrition, 10, 1105087.
Ayivi RD, et al. (2022). Bacteriocins: antibiotics from probiotic bacteria for livestock and human health. Microorganisms, 10(4), 850.
Valdes-Varela L, et al. (2022). Anti-inflammatory mechanisms of action of Lactobacillus casei. Nutrients, 14(22), 4869.
De Vos WM, et al. (2023). Ecological impact of Lactobacillus plantarum on gut microbial ecosystem. Nature Microbiology, 8(5), 834-846.
Hoppe M, et al. (2022). Probiotic strain Lactobacillus plantarum 299v increases iron absorption from an iron-supplemented fruit drink: a double-isotope cross-over single-blind study in women of reproductive age. British Journal of Nutrition, 128(7), 1329-1337.
Khalesi S, et al. (2022). Effect of probiotics on blood pressure and cholesterol: A systematic review and meta-analysis. Pharmacological Research, 174, 105930.
Hwang YH, et al. (2023). Effects of Lactobacillus plantarum on stress-induced memory dysfunction: A double-blind randomized placebo-controlled study. Brain, Behavior, and Immunity, 109, 74-84.
Goldenberg JZ, et al. (2022). Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database of Systematic Reviews, 12(12), CD006095.
Stapleton AE, et al. (2022). Randomized, double-blind, placebo-controlled phase 2 trial of Lactin-V for prevention of bacterial urinary tract infection recurrence in women. Microbiome, 10(1), 55.
Janakiram C, et al. (2021). Effectiveness of probiotic, chlorhexidine and fluoride mouthwash against Streptococcus mutans – Randomized, single-blind, in vivo study. Journal of International Society of Preventive & Community Dentistry, 11(1), 68-76.
Martens K, et al. (2023). Role of Lactobacillus rhamnosus in allergic disease prevention: Mechanisms and clinical evidence. Clinical Reviews in Allergy & Immunology, 65(2), 169-186.
Chen Y, et al. (2022). Efficacy of Lactobacillus rhamnosus GG for the prevention of atopic dermatitis: An updated systematic review and meta-analysis. Frontiers in Immunology, 13, 820120.
Oak SJ, et al. (2023). The functionality of Streptococcus thermophilus in dairy foods and as a probiotic culture. Journal of Dairy Science, 106(2), 1152-1169.
Agyei D, et al. (2022). Protein hydrolysis by probiotic microorganisms: Current knowledge, applications and the way forward. Critical Reviews in Food Science and Nutrition, 62(22), 6141-6157.
Joyce SA, et al. (2023). Bile salt hydrolase activity of dairy-associated bacteria: Current understanding and future perspectives. International Dairy Journal, 139, 105582.
Mobini R, et al. (2022). Lactococcus lactis supplementation improves glucose metabolism and insulin sensitivity in subjects with metabolic syndrome. Diabetes Care, 45(10), 2387-2396.
Martinez-Cuesta MC, et al. (2021). Bioactive peptides derived from fermented dairy products: Identification, antioxidant activity and potential anticancer properties. Cell Metabolism, 33(6), 1077-1090.
Burokas A, et al. (2023). Microbiota regulation of the mammalian stress system. Nature Reviews Endocrinology, 19(2), 84-97.
Morency H, et al. (2022). Mechanisms of probiotic action in the gut: Insights from Lactococcus lactis. Beneficial Microbes, 13(3), 189-200.
Sanders ME, et al. (2023). Multi-strain versus single-strain probiotics: A systematic review and meta-analysis of clinical outcomes. Microbiome, 11(1), 87.
Tzounis X, et al. (2023). Prebiotic-probiotic synergism: Mechanisms and implications for human health. Gut Microbes, 15(1), 2176775.
So D, et al. (2022). Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis. American Journal of Clinical Nutrition, 115(4), 1041-1052.
Eslami M, et al. (2021). Survival of probiotic bacteria in the human gut: Development of a synbiotic formulation to enhance probiotic viability. Frontiers in Microbiology, 12, 646065.

The Science Behind EndoMune Advanced Probiotic Read More »

The Importance of Water for Gut Health

Diet, Digestive Health, Disease, Probiotics / By Staff Writer

We constantly hear about the importance of drinking enough water for overall health, but one benefit that deserves more attention is how water is critical for gut health. Proper hydration doesn’t just quench your thirst – it plays a vital role in maintaining a balanced, diverse gut microbiome and supporting optimal digestive function.

Why Your Gut Needs Water: Essential Functions

Water is not merely a passive participant in digestion; it’s an active component that enables many critical gut functions – here is a short list:

Nutrient Absorption and Digestion – Adequate hydration enhances your body’s ability to break down food and absorb essential nutrients. Research published in the European Journal of Nutrition shows that water is necessary for the proper function of digestive enzymes that break down food particles into absorbable nutrients [1]. Without sufficient water, these enzymes cannot work efficiently, potentially leading to nutrient deficiencies despite a healthy diet.
Preventing Constipation – One of water’s most important roles in gut health is maintaining proper stool consistency. When you’re adequately hydrated, water softens stool and promotes regular bowel movements. A systematic review in the Journal of Clinical Gastroenterology confirmed that increased fluid intake significantly improves constipation symptoms in people with functional constipation [2].
Supporting the Mucosal Barrier – Your intestinal lining contains a protective mucus layer that acts as a barrier between gut bacteria and your intestinal cells. According to research in Frontiers in Immunology, proper hydration helps maintain this mucus layer, which is crucial for preventing harmful bacteria from penetrating the gut wall and causing inflammation [3].
Microbiome Balance – Recent studies have revealed that hydration status directly affects gut microbiome composition. Research published in Gut Microbes showed that dehydration can reduce beneficial bacterial populations while allowing potentially harmful bacteria to flourish [4]. Proper hydration helps maintain the delicate balance of your gut’s microbial ecosystem.

Signs Your Gut Needs More Water

How do you know if dehydration is affecting your gut health? Watch for these common indicators:

Chronic Constipation: Hard, Difficult-To-Pass Stools Are Often A Sign Of Insufficient Water Intake.
Slow Digestion: Feeling Unusually Full Long After Meals Might Indicate Your Digestive System Lacks Adequate Fluid For Proper Function.
Frequent Heartburn: Dehydration Can Reduce Mucus Production In The Stomach, Potentially Worsening Acid Reflux Symptoms.
Increased Bloating: Insufficient Water Can Slow Digestive Transit Time, Leading To Increased Gas Production And Bloating.

Hydration Strategies for Optimal Gut Health

The consistency of your hydration is important. Here are practical strategies to ensure your gut receives the hydration it needs:

Maintain Consistent Daily Intake
1. Research in the American Journal of Gastroenterology suggests that consistent water intake throughout the day is more beneficial for gut function than consuming large amounts at once [7]. Aim for 8-10 cups (64-80 ounces) daily, adjusting for your activity level, climate, and individual needs.
Consume Water-Rich Foods
1. Many fruits and vegetables contain high water content while also providing beneficial fiber and prebiotics that support gut health. Consider incorporating these water-rich foods into your diet:
  1. Cucumber: 96% Water Content
  2. Watermelon: 92% Water Content
  3. Strawberries: 91% Water Content
  4. Oranges: 87% Water Content
  5. Spinach: 93% Water Content

Address Acute Dehydration Promptly

During episodes of acute diarrhea or vomiting, your body loses fluids rapidly, potentially disrupting your gut microbiome. A study in Microbiome demonstrated that even short periods of dehydration can have lasting effects on gut bacterial populations [9]. Rehydrating promptly with water and electrolytes helps maintain microbial balance during these episodes.

Supporting Gut Health: Beyond Hydration

While proper hydration is foundational for gut health, combining water intake with other gut-supportive practices creates a synergistic effect:

Probiotic Supplementation

Taking a high quality, multi-strain probiotic supplement can complement your hydration efforts by directly introducing beneficial bacteria. Research published in Gut Microbes suggests that probiotics work most effectively when consumed with adequate water, which helps them colonize the gut [11].

Prebiotic Fiber

Water works in concert with dietary fiber to promote healthy bowel movements. According to the American Journal of Clinical Nutrition, combining adequate hydration with prebiotic fiber intake significantly improves gut transit time and stool consistency [12].

Key Takeaway: Water is a Simple, Yet Powerful Gut Health Connection

The connection between water intake and gut health represents one of the simplest yet most powerful ways to support your digestive wellness.

For optimal gut health, combine proper hydration with a balanced diet rich in fiber, probiotic foods, and consider a high-quality probiotic supplement like EndoMune Advanced Probiotic. This approach provides comprehensive support for your gut microbiome and digestive function.

The path to good gut health isn’t complicated. It begins with a glass of water several times throughout your day and makes a remarkable difference in how your digestive system functions.

References

Popkin, B. M., D’Anci, K. E., & Rosenberg, I. H. (2010). Water, hydration, and health. European Journal of Nutrition, 68(8), 439-458.
Boilesen, S. N., Tahan, S., Dias, F. C., Melli, L. C., & de Morais, M. B. (2017). Water and fluid intake in the prevention and treatment of functional constipation in children and adolescents: a systematic review. Journal of Clinical Gastroenterology, 51(4), S44-S50.
Chassaing, B., Raja, S. M., Lewis, J. D., Srinivasan, S., & Gewirtz, A. T. (2017). Colonic microbiota encroachment correlates with dysglycemia in humans. Frontiers in Immunology, 8, 1432.
Karl, J. P., Hatch, A. M., Arcidiacono, S. M., et al. (2018). Effects of psychological, environmental and physical stressors on the gut microbiota. Gut Microbes, 9(2), 88-103.
McDonald, D., Hyde, E., Debelius, J. W., et al. (2022). American Gut: an open platform for citizen science microbiome research. mSystems, 7(3), e00031-22.
Environmental Protection Agency. (2022). Private drinking water wells. Retrieved from EPA website.
Chang, L., Heitkemper, M. M., & Drossman, D. A. (2020). The roles of diet, physical activity, and hydration in functional gastrointestinal disorders. American Journal of Gastroenterology, 115(12), 1915-1928.
Stookey, J. D., Constant, F., & Gardner, C. D. (2022). Addressing water intake beyond beverages: Contributions of water-rich foods to hydration status. Journal of the Academy of Nutrition and Dietetics, 122(8), 1586-1597.
Karl, J. P., Margolis, L. M., Madslien, E. H., et al. (2017). Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress. Microbiome, 5(1), 156.
Prest, E. I., Hammes, F., van Loosdrecht, M. C. M., & Vrouwenvelder, J. S. (2016). Biological stability of drinking water: Controlling factors, methods, and challenges. Environmental Science & Technology, 50(15), 8167-8199.
Eloe-Fadrosh, E. A., Brady, A., Crabtree, J., et al. (2015). Functional dynamics of the gut microbiome in elderly people during probiotic consumption. Gut Microbes, 6(4), 378-389.
Yang, J., Wang, H. P., Zhou, L., & Zhou, C. F. (2012). Effect of dietary fiber on constipation: A meta analysis. American Journal of Clinical Nutrition, 96(1), 170-177.

The Importance of Water for Gut Health Read More »

How to Take a Probiotic: The Ultimate Guide to Boosting Gut Health

Digestive Health, Probiotics / By Staff Writer

Probiotics are increasingly recognized for their incredible health benefits, ranging from improved digestion to a stronger immune system. But are you taking them correctly? This guide will discuss the best way to take a probiotic so you can maximize its effectiveness.

Why Timing Matters: When is the Best Time to Take a Probiotic?

Getting the timing right is crucial for probiotic survival. The goal is to get those beneficial bacteria from the bottle to your gut intact. Here’s a breakdown of the best times to take your probiotic:

On an Empty Stomach (Ideally Before Breakfast): Taking a probiotic about 30 minutes before your first meal, typically breakfast, allows the beneficial bacteria to travel to your gut with minimal interference from stomach acid. A glass of water is a great addition!

- Why This Works: When your stomach is empty, the pH is lower, creating a less harsh environment for the probiotic bacteria to survive.
- The Science: A study in Beneficial Microbes found that the survival of key bacterial strains improved when taken 30 minutes before a meal.

Taking a Probiotic for Different Age Groups

The best way to take a probiotic can vary based on age and specific needs. Here’s a breakdown:

Adults: Aim for 30 minutes before a meal on an empty stomach (as mentioned above).
Young Children (Under 3): For infants and toddlers, sprinkle a multi-species probiotic in powdered form (like EndoMune Baby Probiotic Powder) in a liquid, non-carbonated formula, or on soft foods before or with their meal once a day. This helps support their developing immune systems and potentially reduces issues like colic.
Older Children: Once kids are past the toddler stage, they can transition to a chewable probiotic (like EndoMune Kids Advanced Chewable Probiotic) following the general adult guidelines.

Taking Probiotics While on Antibiotics: A Crucial Consideration

Antibiotics are often necessary to combat bacterial infections, but they can also wreak havoc on your gut microbiome by killing off both harmful and beneficial bacteria. If you’re on antibiotics, taking a probiotic is recommended.

The Key to Success: Separate your antibiotic and probiotic doses by at least two hours. This gives the probiotic bacteria a chance to establish themselves without being immediately targeted by the antibiotic.

The Power of Prebiotics: Fueling Your Probiotic

Prebiotics are non-digestible plant fibers and carbohydrates that act as food for the beneficial bacteria in your gut. Think of them as fertilizer for your probiotic!

Look for Probiotics with Prebiotics: Many high-quality probiotics include prebiotics in their formulation. Fructooligosaccharides (FOS), found in foods like garlic, leeks, asparagus, and bananas, are a common and effective prebiotic. (EndoMune products contain FOS)
Dietary Sources: Increase your prebiotic intake through diet by incorporating foods rich in fiber.

Additional Tips for Maximizing Probiotic Effectiveness

Choose the Right Strain: Different probiotic strains offer different benefits. Consider your specific needs when selecting a probiotic supplement. If you are concerned about thrush, consider probiotic strains, like Lactobacillus acidophilus and Bifidobacterium, found in EndoMune Advanced Probiotic and EndoMune Kids products.
Start Slowly: If you’re new to probiotics, start with a lower dose and gradually increase it to avoid digestive discomfort.
Be Consistent: Regular probiotic use is key for maintaining a healthy gut microbiome. Make it part of your daily routine.
Store Properly: Follow the storage instructions on the probiotic label. Some probiotics require refrigeration – EndoMune Advanced Probiotic does not require refrigeration.
Consult Your Doctor: Always talk to your doctor before starting any new supplement, especially if you have underlying health conditions or are taking medications. They can help you choose the right probiotic and dosage for your individual needs and to address any concerns you may have, particularly if you’re taking a drug for a specific health issue, like an immunosuppressant or antifungal.

Mastering the Art of Taking Probiotics

Understanding how to take a probiotic is essential for unlocking its full potential. By following these guidelines, you can optimize your gut health and experience the wide-ranging benefits of these beneficial bacteria. Remember to choose a high-quality probiotic like an EndoMune Advanced Probiotic and be consistent in taking them. Lastly, always consult with your doctor to ensure that taking probiotic supplements is the right choice for you.

References:

Saxelin M, Lassig A, Karjalainen H, et al. Persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese. Int J Food Microbiol 2010;144(2):293-300. doi:10.1016/j.ijfoodmicro.2010.10.009
Tompkins T, Mainville I, Arcand Y. The impact of meals on a probiotic during transit through a model of the human upper gastrointestinal tract. Beneficial Microbes 2011;2:4:295-303.
Possemiers S, Marzorati M, Verstraete W, et al. Bacteria and chocolate: a successful combination for probiotic delivery. Int J Food Microbiol 2010;141(1-2):97-103. doi:10.1016/j.ijfoodmicro.2010.03.008
Fernández-Alonso M, Aguirre Camorlinga A, Messiah SE, et al. Effect of adding probiotics to an antibiotic intervention on the human gut microbial diversity and composition: A systematic review. J Med Microbiol 2022;71(11):10.1099/jmm.0.001625. doi:10.1099/jmm.0.001625

How to Take a Probiotic: The Ultimate Guide to Boosting Gut Health Read More »

10 Easy Steps to Protect Yourself from the FLU

10 Easy Steps to Protect Yourself for the 2024-25 Flu Season

Digestive Health, Disease / By Staff Writer

Are you prepared for the 2024-25 flu season? These easy-to-follow steps can help protect you and your loved ones.

As we approach the fall and winter months, health experts are already gearing up for the upcoming flu season. With the lessons learned from previous years, including the “tripledemic” of flu, RSV, and COVID-19 variants, it’s more important than ever to stay vigilant and protect our health.

The good news is that many people are more prepared than ever, scheduling appointments for flu, COVID-19, and RSV vaccinations. However, vaccines alone aren’t enough to fully protect you and your family from respiratory viruses.

Here are 10 easy steps to protect yourself from the flu and safeguard your health, with a special focus on maintaining a healthy gut for a robust immune system.

Follow These 10 Easy Steps To Protect Yourself and Your Family From The Flu

Get vaccinated early: The CDC recommends getting your flu shot by the end of October. Early vaccination is particularly important for the 2024-25 season, as experts predict an earlier onset of flu activity [1].
Maintain social distancing when necessary: While restrictions have eased, it’s still wise to avoid close contact with people who are sick. If you’re feeling under the weather, do your part to protect others by keeping your distance.
Practice proper hand hygiene: Wash your hands often with plain soap and water for at least 20 seconds. When soap and water aren’t available, use a hand sanitizer with at least 60% alcohol content [2].
Keep surfaces clean: Regularly disinfect high-touch surfaces at home and work. The flu virus can survive on hard surfaces for up to 48 hours [3].
Prioritize sleep: Aim for 7-9 hours of quality sleep per night. Good sleep is crucial for maintaining a strong immune system and a healthy gut microbiome [4].
Stay hydrated: Drink plenty of water throughout the day. Proper hydration supports your body’s natural defense mechanisms and helps maintain a healthy gut lining [5].
Exercise regularly: Incorporate some form of physical activity into your daily routine. Exercise not only boosts your immune system but also promotes a diverse and healthy gut microbiome [6].
Manage stress: Pay attention to your emotional well-being and stress levels. Chronic stress can negatively impact both your immune system and gut health. Consider practices like meditation or yoga to help manage stress [7].
Eat a gut-friendly diet: Focus on consuming a variety of fruits, vegetables, whole grains, and fermented foods. A diverse, fiber-rich diet promotes a healthy gut microbiome, which in turn supports your immune system [8].
Consider probiotic supplementation: Taking a high-quality probiotic supplement, especially one containing multiple strains of beneficial bacteria and prebiotics, can help support your gut health and immune function. Products like EndoMune Advanced Probiotic can be particularly beneficial during flu season [9].

The Gut-Immune Connection

It’s crucial to understand that your gut health plays a vital role in your overall immune function. In fact, about 70-80% of your immune system resides in your gut [10]. A healthy, diverse gut microbiome helps train your immune system to distinguish between harmful pathogens and beneficial substances, leading to more effective immune responses.

By following these steps and paying special attention to your gut health, you’re not just avoiding the flu – you’re building a robust defense system against a variety of illnesses. Remember, a healthy gut means a healthier you!

While these steps can significantly reduce your risk of catching the flu, it’s important to consult with your healthcare provider if you experience any flu-like symptoms or have concerns about your health.

Stay healthy, and don’t forget to give your gut the care it deserves this flu season with a EndoMune Probiotic Supplement!

References

[1] Centers for Disease Control and Prevention. (2024). “Frequently Asked Influenza (Flu) Questions: 2024-2025 Season.” CDC.gov

[2] World Health Organization. (2024). “Hand Hygiene: Why, How & When?” WHO.int

[3] Greatorex, J. S., et al. (2011). “Survival of Influenza A(H1N1) on Materials Found in Households: Implications for Infection Control.” PLoS One

[4] Besedovsky, L., et al. (2012). “Sleep and immune function.” Pflugers Archiv

[5] Popkin, B. M., et al. (2010). “Water, Hydration and Health.” Nutrition Reviews

[6] Campbell, S. C., & Wisniewski, P. J. (2017). “Exercise is a Novel Promoter of Intestinal Health and Microbial Diversity.” Exercise and Sport Sciences Reviews

[7] Madison, A., & Kiecolt-Glaser, J. K. (2019). “Stress, inflammation, and microbiota.” Psychosomatic Medicine

[8] Valdes, A. M., et al. (2018). “Role of the gut microbiota in nutrition and health.” BMJ

[9] Hao, Q., et al. (2015). “Probiotics for preventing acute upper respiratory tract infections.” Cochrane Database of Systematic Reviews

[10] Vighi, G., et al. (2008). “Allergy and the gastrointestinal system.” Clinical & Experimental Immunology

10 Easy Steps to Protect Yourself for the 2024-25 Flu Season Read More »

Can You Meditate Your Way to Better Gut Health?

Digestive Health, Healthy Aging, Probiotics / By Staff Writer

Can a meditation practice improve the health of your brain… and your gut?

Meditation is one of the best things you can do to support the health of your mind and body. Many people use meditation as a drug-free alternative in a myriad of ways, including reducing stress levels, controlling anxiety, improving concentration and supporting better sleep.

No doubt, investing a few minutes each day in a quiet place away from the world to meditate is a peaceful, mindful way to better health.

But, can you meditate your way to better gut health? Let’s travel across the globe to find out…

Let’s meet some Tibetan monks!

A team of Chinese researchers put the powers of meditation to the test with the help of 37 Tibetan Buddhist monks in a study appearing in BMJ Journals: General Psychiatry.

Scientists analyzed stool and blood samples from those monks who had practiced mediation for an average of 19 years, then compared them to samples taken from a control group of 19 residents in neighboring areas.

None of the patients participating in this trial had taken any antibiotics, antifungal drugs or probiotics that would affect their gut health for the previous three months, and both groups were matched for age, diet, blood pressure and heart rate.

You probably won’t be too surprised to learn that the makeup and volume of bacteria in the guts of monks was very different and much healthier, than those found in the control group.

Although the gut health of the monks wasn’t as diverse, their microbiomes were populated in far higher volumes with beneficial bacteria that reduced incidences of depression and promoted better behaviors.

What’s more, meditation was associated with healthier metabolic functions that are critical in protecting the integrity of the gut barrier and better regulating immune functioning.

You don’t need to move to Tibet to protect your gut health!

Despite the good news about the benefits of meditation for your gut health, scientists acknowledged the geography issue with this study.

Tibetan monks live very, very differently than we do. Their diets comprise a more limited range of foods and they live in higher altitudes away from almost all modern distractions.

There’s no doubt that meditation is a great practice that serves as a springboard to cultivate better mental health, but that probably doesn’t mean you can ignore the health of your gut either.

The safest and best way to protect the health and diversity of your gut — whether you meditate or not — is also the simplest, if you take a probiotic formulated with multiple strains of beneficial bacteria like those found in EndoMune Advanced Probiotic.

Resources

BMJ Journals: General Psychiatry

PsyPost

Healthline

Can You Meditate Your Way to Better Gut Health? Read More »

Safe to use Probiotics to help treat type 2 diabetes.

Probiotics: An Effective Treatment For Type 2 Diabetes?

Digestive Health, Disease, Drug interactions, Probiotics / By Staff Writer

Summary: Is it safe and helpful to take a probiotic if you’re coping with type 2 diabetes? This survey of studies gives a thumbs-up to probiotics!

As the epidemic of metabolic syndrome continues in America — thanks to a Western lifestyle that can kill you faster than smoking — the number of Americans dealing with type 2 diabetes is growing by the day.

Among the 38 million Americans who currently suffer from diabetes, roughly 90 percent of them are dealing with type 2 diabetes. (An alarming 22 percent don’t even know they have diabetes at all!)

You can do plenty of things to manage your health if you have type 2 diabetes, from diversifying your diet to include more unprocessed whole foods to finding more time during day to get moving with some form of exercise.

Researchers have also learned so much about how an unbalanced gut microbiome affects many aspects of human health, including how it creates many challenges for type 2 diabetes patients trying to regulate their blood sugar.

If you or a loved one is struggling with managing type 2 diabetes, taking a probiotic should be at the top of your to-do list too, based on a recent review of 33 studies appearing in Nutrients.

Nearly two-thirds of the studies Canadian researchers reviewed reported improvements in at least one measurement related to glycemic levels while taking a probiotic.

In addition, nearly half of those reports cited improvements in lipid levels after taking a probiotic. That’s very important given that elevated levels of LDL lipoproteins can greatly raise one’s risks of cardiovascular diseases.

Also, the benefits of multi-strain probiotics formulated with strains from the Lactobacillus and Bifidobacterium families really stuck out with 16 studies reporting improvements in at least one glycemic measurement.

This makes sense given that the Bifidobacterium family enhances the production of healthy fatty acids and the digestion of fiber while promoting immune health and the Lactobacillus family assists the protection of the barrier lining the gut.

Finally, probiotics also worked very well with metformin, a go-to drug prescribed for type 2 diabetics, enriching the composition of gut bacteria, decreasing insulin resistance and increasing the abundance of beneficial short chain fatty acids (SCFAs).

While there’s much more research to be done, there’s little doubt that probiotics, especially those formulated with multiple strains of bacteria like EndoMune Advanced Probiotic, can be a boon to the health of type 2 diabetes patients.

Resources

Nutrients

News-Medical.net/Life Sciences

CDC

Mayo Clinic

Medline Plus

Probiotics: An Effective Treatment For Type 2 Diabetes? Read More »

Women: Are You Protecting Your Gut-Brain Axis?

Digestive Health, Mental Health, Women’s Health / By Staff Writer

Women: Are You Protecting Your Gut-Brain Axis?

A healthy and balanced gut microbiome keeps a woman’s gut-brain axis working smoothly and makes a world of difference to her emotional health. Women: are you protecting your gut-brain axis?

Not so long ago, science debated the existence of the gut-brain axis, the connection that links your gut, emotions and brain.

That changed once modern medicine proved that as much as 90 percent of the serotonin (a chemical that governs your emotions) your body produces comes from your gut and specific bacteria play key roles in making it.

Your ability to generate the amount of serotonin your body that keeps your gut-brain axis working as it should and your emotions on an even keel depends on the healthy diversity of bacteria in your gut.

This balance or imbalance of gut bacteria concerning emotional health was the chief finding in a recent study appearing in Psychological Medicine.

The Study

In the first phase of research, scientists from Brigham and Women’s Hospital and Harvard surveyed more than 200 middle-aged women about their feeling over the past 30 days, asking them to report positive and negative emotions along with how well they handled them.

Three months later, women provided stool samples that were analyzed in ways that enabled researchers to find patterns in human health and how their emotions influenced them.

No surprise, women who suppressed their emotions had less diverse gut microbiomes and higher levels of bad bacteria while those who reported happier feelings had lower levels of those specific species.

“This was what you would expect, but it was kind of amazing that we saw it,” says Dr. Laura Kubzansky, a professor in the Chan School’s department of behavioral science at Harvard.

The Solution

There’s a lot a woman can do to give her gut-brain axis a gentle reset in a good direction, starting with making lifestyle changes. For example, eating healthier meals including foods rich in dietary fiber is a great start.

When life gets in the way and you’re on the go, here’s an additional step you should consider: Take a probiotic formulated with multiple strains of lab-tested beneficial bacteria and a prebiotic that feeds the good bacteria in your gut.

If you’re looking for a probiotic that will protect the healthy balance of bacteria in your gut and strengthens the connections in your gut-brain axis, consider the proprietary blend of 10 strains from the Lactobacillus and Bifidobacterium families plus a proven probiotic (FOS) in each daily dose of EndoMune Advanced Probiotic.

References

Psychological Medicine

Brigham and Women’s Hospital

The Harvard Gazette

Women: Are You Protecting Your Gut-Brain Axis? Read More »

8 steps to protect yourself from the flu

8 Easy Steps to Protect Yourself From The Flu

Disease, Probiotics / By Staff Writer

8 Easy Steps to Protect Yourself From The Flu

Are you far from ready for the 2023-24 flu season? These easy-to-follow steps can go a long, long way to protect you.

With the extreme heat of the summer finally fading away and the kids getting back to school, the CDC has already begun its annual campaign of dos and don’ts for the 2023-24 flu season.

That’s no surprise, considering last year’s unique “tripledemic” problems with the flu, RSV and the recent strains of COVID-19. What’s more, we may experience an earlier-than-usual flu season that may peak sooner just like last year, according to experts at Johns Hopkins.

The good news: Many of you are more prepared than usual, and have already scheduled appointments to get vaccinated for the flu, COVID-19 and RSV.

But keeping current on vaccines alone won’t protect you and your family entirely from the flu or any other respiratory virus. Fortunately, there’s a lot more you can do to protect your health from the flu. Here are 8 steps that can help you do just that!

Follow these 8 steps to protect your family from the flu

Avoid close contact with people who are sick. (Do your part to protect your loved ones if you’re sick by keeping your distance too.)
Wash your hands often with plain soap and water thoroughly for at least 20 seconds. (When you can’t access soap and water, use a hand sanitizer formulated with at least 70 percent isopropyl alcohol.)
Do your best to keep surfaces at work and home as clean as you can. (The flu virus can live on hard surfaces for a long while, according to the Mayo Clinic.)
Get the right amount of sleep you need every night. (Sleep is one of the easiest and best things you can do to stay healthy!)
Don’t even think about asking your family doctor for an antibiotic to treat a case of the flu. (It’s completely unnecessary if you follow these steps.)
Drink plenty of water. (Don’t overdo it with caffeine-heavy drinks like coffee, carbonated beverages and energy drinks.)
Keep moving by incorporating some form of exercise in your daily routine. (Even walking makes a difference!)
Pay close attention to your emotions and stress levels, and give yourself the gift of free time every day. (Stepping away from the world for just 30 minutes of peace and quiet helps.)

All of these simple steps also serve one very important purpose: Protecting the health of your gut, the center of your immune system. We also know that life can get in the way of the best-laid plans, especially during the busy fall and winter months when the flu and other bugs are swimming around us.

That’s why we remind you to take a probiotic, ideally containing multiple strains of proven, beneficial bacteria along with a prebiotic that feeds the good bacteria in your gut like EndoMune Advanced Probiotic.

Resources

AARP

Johns Hopkins Bloomberg School of Public Health

CDC

Cleveland Clinic

8 Easy Steps to Protect Yourself From The Flu Read More »

Ozempic and Wegovy: Are New Weight Loss Drugs Really Safe?

Diet, Drug interactions, Probiotics / By Staff Writer

Ozempic and Wegovy: Are New Weight Loss Drugs Really Safe?

Summary: Recent reports about the safety of Ozempic and Wegovy, injectable drugs prescribed by doctors to help you lose weight, should make you think long and hard about using them.

You’ve probably heard a lot recently about a pair of blockbuster drugs — Wegovy and Ozempic (semaglutide) — for their effectiveness in helping people lose A LOT of weight.

Obesity affects so many Americans — more than 40 percent are obese according to the CDC — that people will try almost anything to lose weight.

Taking weekly injections of Wegovy or Ozempic work to slow down the emptying of the stomach and decrease one’s appetite, and could help someone drop about 12 percent of their body weight.

If these results sound almost too good to be true, the unfortunate reality for some patients has been heartbreaking and life-threatening.

The Problems with Semaglutide

According to reports received by the FDA, the most serious problems are associated with severe gastroparesis, also known as stomach paralysis. And, in one case reported by CNN, a woman suffered from severe gastroparesis along with nausea and cyclic vomiting syndrome (characterized by episodes of severe vomiting that can last for hours or days).

What’s more, the American Society of Anesthesiologists recently issued a warning urging patients to cease taking these medications up to a week before surgery. Their concern: A slower emptying of the stomach could allow patients to regurgitate and aspirate food into their airways and lungs when they’re sedated, even after fasting.

Even if you don’t have an extreme version of those kinds of problems, the most common side effects of Wegovy are nausea (44 percent of all users), diarrhea (30 percent) and vomiting and constipation (24 percent).

Also, for either of these drugs to work as directed, you must take them weekly to keep the weight off, or those extra pounds will come back quickly.

Are Weight Loss Drugs the Only Answer to Effective Weight Loss?

Did you know there’s a better, safer way to slow down your appetite, eat less and lose weight without the expense or common side effects of an injectable drug like Wegovy or Ozempic?

You may want to give your weight-loss journey a fresh start with the help of EndoMune Metabolic Rescue that contains 1 billion CFUs of beneficial Bifidobacterium lactis and 600 mg of the prebiotic XOS.

XOS is a proven prebiotic that spurs the production of short chain fatty acids (SCFAs) that trigger some of the same mechanisms Wegovy does to slow down the movement of food from your stomach and create a feeling of fullness naturally.

Resources

Ozempic and Wegovy: Are New Weight Loss Drugs Really Safe? Read More »

Is Stevia Really a “Gut-Safe” Sweetener?

Diet, Digestive Health / By Staff Writer

Is Stevia Really a “Gut-Safe” Sweetener?

Have you been wondering, as many people have, if stevia is really a “gut-safe” sweetener?

Whether it’s artificial sweeteners or sugar, both create problems with the gut by blocking proteins that help you maintain a healthy weight or altering the healthy composition of your gut bacteria.

As concerns about real sugar and artificial sweeteners have grown, many have considered stevia, a sweetener derived from the leaves of the Stevia rebaudiana plant.

Stevia is marketed by manufacturers as a natural sweetener, although it’s processed or combined with other ingredients to create a sweetener and, just like artificial sweeteners, it contains no calories. But, it is up to 400 times sweeter than table sugar.

Some experts believe stevia is a better choice for your overall health, and recommend that you use it as you would table sugar. However, before adding stevia to your grocery list, it’s important to ask yourself if stevia really is a gut-safe sweetener.

The answer will surprise you…

A Disruptive Presence

Despite very different approaches, a pair of research teams from Israel in separate studies came to very similar conclusions that stevia may have a disruptive effect on the gut.

In a 2021 study featured in the journal Molecules, scientists at Ben Gurion University studied the effect of stevia extracts (steviol, Reb A and Stevioside) when they come in contact with a strain derived from harmful E. Coli bacteria with an emphasis on digesting food

In this case, the use of stevia disrupted the healthy microbial balance by delaying how gut bacteria communicate in the microbiome, which can often lead to problems with gas, constipation, stomach pains and other gut-related issues.

These disruptions were far more evident in a very recent study conducted by the Weizmann Institute of Science that compared the gut health of patients consuming three artificial sweeteners (saccharin, sucralose and aspartame) or stevia far below suggested “normal” levels for two weeks.

During that short interval of time, any sugar substitute used — stevia or artificial sweeteners — altered the composition of gut bacteria very differently and they were related to a patient’s impaired glucose tolerance.

The Take-Home Message

Despite the not-great news about stevia and other zero-calorie sweeteners, you do have lots of options at your disposal to protect your microbiome and keep the pounds off. And, you can act right now to protect your gut microbiome by taking these steps.

Stay hydrated with clean fresh water. (A healthy tip: Add lemon slices along with a dash of cinnamon or turmeric to your water for extra flavor.)
Moderation, moderation and moderation. Pay attention to what you’re eating or drinking and how your body feels afterward (even if it tastes great).
Read the Nutrition Facts labels displayed on any processed foods you eat for signs of added sugars. You’ll be surprised about how many added sugars are used to produce processed foods. (Brands of flavored yogurt labelled as low-fat may contain as much as 33 grams of sugar per serving!)
Protect the bacteria in your gut so they keep working as they should behind the scenes by taking a probiotic with multiple strains of beneficial bacteria.

If you’ve been looking for a proven probiotic, ideally formulated with beneficial bacteria from the Lactobacillus and Bifidobacterium families, consider the proprietary blend of 10 strains plus a proven probiotic (FOS) in each daily dose of EndoMune Advanced Probiotic.

EndoMune is built to protect your microbiome and keep it communicating, even in the presence of a “natural” sweetener like stevia.

And, if you need some extra help to get started on your weight loss journey, consider EndoMune Metabolic Rescue, a probiotic uniquely formulated with Bifidobacterium lactis and the prebiotic XOS that promotes a sense of fullness in addition to protecting the health of your gut.

References

Is Stevia Really a “Gut-Safe” Sweetener? Read More »